Apoptotic-like mitochondrial events associated to phosphatidylserine exposure in blood platelets induced by local anaesthetics

Thrombosis and Haemostasis

Volumn 92, Issue 1, 2004, Pages 104-113

  Augereau, Olivier ^a   Rossignol, Rodrigue ^a   DeGiorgi, Francesca ^b   Mazat, Jean Pierre ^a   Letellier, Thierry ^a   Dachary Prigent, Jeanne ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

Author keywords

Apoptosis; Phospholipids procoagulant; Platelet physiology; Signal transduction

Indexed keywords

CALCIMYCIN; CALCIUM ION; CALPAIN; CASPASE 3; CASPASE 9; CINCHOCAINE; CYTOCHROME C; LIDOCAINE; LOCAL ANESTHETIC AGENT; PHOSPHATIDYLSERINE; TETRACAINE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SECRETION; THROMBOCYTE FUNCTION;

EID: 3542991453     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/th03-10-0631     Document Type: Article

References (44)

1. Zwaal RF. Membrane involvement in blood coagulation. Biochim Biophys Acta 1978; 515: 163-205.
2. 2+ induces transbilayer redistribution of all major phospholipids in human erythrocytes. Biochemistry 1992; 14: 6355-60.
3. Zwaal RF, Comfurius P, Bevers EM. Mechanism and function of changes in membrane-phospholipid asymmetry in platelets and erythrocytes. Biochem Soc Trans 1993; 21: 248-53.
4. 2+-dependent transbilayer movement of phospholipid. J Biol Chem 1996; 271: 17205-10.
5. Fadok VA, Bratton DL, Frasch SC, et al. The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell Death Differ 1998; 5: 549-50.
6. Bertino AM, Qi XQ, Li J, et al. Apoptotic markers are increased in platelets stored at 37 degrees C. Transfusion 2003; 43: 857-66.
7. Leytin V, Freedman J. Platelet apoptosis in stored platelet concentrates and other models. Transfus Apheresis Sci 2003; 28: 285-95.
8. Wolf BB, Goldstein JC, Stennicke HR, et al. Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood 1999; 94: 1683-92.
9. Scherbina A, Remold-O'-Donnell E. Role of caspase in a subset of human platelet activation responses. Blood 1999; 93: 4222-31.
10. Bratton DL, Fadok VA, Richter DA, et al. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase. J Biol Chem 1997; 272: 26159-65.
11. Williamson P, Christie A, Kohlin T, et al. Phospholipid scramblase activation pathways in lymphocytes. Biochemistry 2001; 40: 8065-72.
12. Verhallen PF, Bevers EM, Comfurius P, et al. Correlation between calpain-mediated cytoskeletal degradation and expression of platelet procoagulant activity. A role for the platelet membrane-skeleton in the regulation of membrane lipid asymmetry? Biochem Biophys Acta 1987; 903: 206-17.
13. Dachary-Prigent J, Freyssinet J-M, Pasquet J-M, et al. Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups. Blood 1993; 8: 2554-65.
14. Arita K, Utsumi T, Kato A, et al. Mechanism of dibucaine-induced apoptosis in promyelocytic leukemia cells (HL-60). Biochem Pharm 2000; 60: 905-15.
15. He J, Xiao Y, Casiano CA, et al. Role of mitochondrial cytochrome c in cocaine-induced apoptosis in coronary artery endothelial cells. J Pharmacol Exp Therapy 2000; 295: 896-903.
16. Sztark F, Tueux O, Erny P, et al. Effects of bupivacaine on cellular oxygen consumption and adenine nucleotide metabolism. Anesth Analg 1994; 78: 335-39.
17. Grouselle M, Tueux O, Dabadie P, et al. Effect of local anaesthetics on mitochondrial membrane potential in living cells. Biochem J 1990; 271: 269-72.
18. Sztark F, Malgat M, Dabadie P, et al. Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergetics. Anesthesiology 1998; 88: 1340-9.
19. Pulselli R, Arcuri E, Paggi MG, et al. Changes in membrane potential induced by local anesthetic bupivacaine on mitochondria within Ehrlich ascites tumor cells. Oncol Res 1996; 8: 267-71.
20. Garcia-Martin E, Escudero B, Fernandez-Salguero P, et al. Modulation of (Ca2+ +Mg2+)-ATPases and Ca2+ fluxes through the plasma membrane of synaptosomes and sarcoplasmic reticulum by local anaesthetics. Biochem Soc Trans 1989; 17: 960-2.
21. Barghouthi SA, Puri RK, Eftink MR. Local anesthetic-phospholipid interactions. Effects of ionic strength, temperature, and phospholipid mixtures on the binding of dibucaine to phospholipids. Biophys Chem 1993; 46: 1-11.
22. Papahadjopoulos D, Jacobson K, Poste G, et al. Effect of local anesthetics on membrane properties. Change in the fluidity of phospholipid bilayers. Biochim Biophys Acta 1975; 394: 504-19.
23. Ronot X, Benel L, Adolphe M, et al. Mitochondrial analysis in living cells: the use of rhodamine 123 and flow cytometry. Biol Cell 1986; 57: 1-7.
24. McIntyre JC, Sleight RG. Fluorescence assay for phospholipid membrane asymmetry. Biochemistry 1991; 30: 11819-27.
25. 2+-ATPase inhibitors. Biochemistry 1995; 36: 11625-34.
26. Chazotte B, Vanderkooi G. Multiple sites of inhibition of mitochondrial electron transport by local anaestheticss. Biochim Biophys Acta 1981; 636:153-61.
27. Chua BT, Guo K, Li P. Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases. J Biol Chem 2000; 275: 5131-5.
28. Ichas F, Mazat JP. From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta 1998; 1366: 33-50.
29. Low PS, Lloyd DH, Stein TM, et al. Calcium displacement by local anaestheticss. J Biol Chem 1979; 254: 4119-25.
30. Takara D, Sanchez GA, Alonso GL. Effect of carticaine on the sarcoplasmic reticulum triphosphatase. Naunyn Schmiedebergs Arch Pharmacol 2000; 362: 497-503.
31. 2+ regulation: potential mechanisms of its myotoxicity. Anesthesiology 2002; 97: 710-6.
32. Dawson AP, Fulton DV. The action of nupervacaine on calcium efflux from rat liver mitochondria. Biochem J 1980; 188: 749-55.
33. 2+ from uncoupled heart mitochondria. Arch Biochem Biophys 1983; 223: 120-8.
34. 2+-dependent transbilayer migration of membrane phospholipids. J Clin Invest 1997; 99: 2232-8.
35. Meisenholder GW, Martin SJ, Green DR, et al. Events in apoptosis. Acidification is down-stream of protease activation and BCL-2 protection. J Biol Chem 1996; 271: 16260-2.
36. Rodeau JL, Flament S, Browaeys E, et al. Effect of procaine on membrane potential and intracellular pH in Xenopus laevis oocytes. Mol Membr Biol 1998; 15: 145-51.
37. Frasch SC, Henson PM, Kailey JM, et al. Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase C delta. J Biol Chem 2000; 275: 23065-73.
38. Kagan VE, Fabisiak JP, Shvedova AA, et al. Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis. FEBS Lett 2000; 477: 1-7.
39. Dachary-Prigent J, Pasquet JM, Freyssinaud E, et al. Aminophospholipid exposure, microvesiculation in the platelets of a patient with Scott syndrome : a study using phisiologic agonists and local anesthetics. Brit J Haematol 1997; 99: 959-67.
40. Breslin DS, Martin G, Macleod DB, et al. Central nervous system toxicity following the administration of levobupivacaine for lumbar plexus block: A report of two cases. Reg Anesth Pain Med 2003; 28: 144-7.
41. Zurbano MJ, Heras M, Rigol M, et al. Cocaine administration enhances platelet reactivity to subendothelial components: studies in a pig model. Eur J Clin Invest 1997; 27: 116-20.
42. Closse C, Dachary-Prigent J, Boisseau MR. Phosphatidylserine-related adhesion of humain erythocytes to vascular endothelium. Brit J Haematol 1999; 107: 300-2.
43. Hultin MB, Hennessey J, Morrison SA. Dibucaine elicits platelet procoagulant activity in factor VIII and factor X activation by a mechanism involving a sulphydryl-dependent enzyme. Thromb Res 1992; 68: 399-407.
44. Heesch CM, Wilhem CR, Ristich J, et al. Cocaine activates platelets and inceases the formation of circulating platelets containing microaggregates in humains. Heart 2000; 83: 388-95.