The Use of Toxicokinetic Data in Preclinical Safety Assessment: A Toxicologic Pathologist Perspective

Toxicologic Pathology

Volumn 35, Issue 6, 2007, Pages 834-837

  Ploemen, Jan Peter H T M ^a   Kramer, Hester ^b   Krajnc, Ernö I ^a   Martin, Iain ^c  

^a Department of Toxicology & Drug Disposition ^*  (Netherlands)

^b Clinical Pharmacology and Kinetics   (Netherlands)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

drug development; Pharmacokinetics; risk assessment; toxicokinetics; toxicological pathology

Indexed keywords

ANIMAL; ARTICLE; DOSE RESPONSE; FEMALE; HUMAN; MALE; PHARMACOKINETICS; RISK ASSESSMENT; SEXUAL DEVELOPMENT; TOXICOLOGY; AREA UNDER THE CURVE; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG METABOLISM; PATHOLOGIST; PREDICTION; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TOXICOKINETICS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; PHARMACOKINETICS; RISK ASSESSMENT; SEX CHARACTERISTICS; TOXICOLOGY;

EID: 35349016777     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230701584247     Document Type: Article

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