The effects of overfeeding and moderate dietary restriction on Sprague-Dawley rat survival, pathology, carcinogenicity, and the toxicity of pharmaceutical agents

Experimental and Toxicologic Pathology

Volumn 48, Issue 2-3, 1996, Pages 139-144

  Keenan, K P ^a   Laroque, P ^b   Soper, K A ^b   Morrissey, R E ^b   Dixit, R ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

Carcinogenicity, food consumption; Dietary restriction; Food consumption, carcinogenesis and survival; Overfeeding; Survival, diet; Toxicity, pharmaceutical agents

Indexed keywords

RATTUS NORVEGICUS; RODENTIA;

CLOFIBRATE; CYCLOSPORIN A; DOPAMINE RECEPTOR STIMULATING AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; L 647318; MK 0458; PHENOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BIOASSAY; BODY WEIGHT; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; DIETARY INTAKE; FEEDING; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SURVIVAL; TOXICOKINETICS;

EID: 0029922349     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-2993(96)80034-0     Document Type: Article

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