메뉴 건너뛰기




Volumn 150, Issue 2, 2007, Pages 230-237

Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis

Author keywords

Ascitic fluid; Bacterial DNA; Cirrhosis; Cytokines; NF B

Indexed keywords

BACTERIAL DNA; CYTOKINE; CYTOSINE; GUANOSINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 35349016366     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03494.x     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 18444391187 scopus 로고    scopus 로고
    • Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites
    • Such J, Frances R, Munoz C et al. Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites. Hepatology 2002 36 : 135 41.
    • (2002) Hepatology , vol.36 , pp. 135-41
    • Such, J.1    Frances, R.2    Munoz, C.3
  • 2
    • 10744233624 scopus 로고    scopus 로고
    • A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites
    • Frances R, Benlloch S, Zapater P et al. A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites. Hepatology 2004 39 : 484 91.
    • (2004) Hepatology , vol.39 , pp. 484-91
    • Frances, R.1    Benlloch, S.2    Zapater, P.3
  • 3
    • 33748928776 scopus 로고    scopus 로고
    • The detection of bacterial DNA in blood of rats with CCl(4)-induced cirrhosis with ascites represents episodes of bacterial translocation
    • Guarner C, Gonzalez-Navajas JM, Sanchez E et al. The detection of bacterial DNA in blood of rats with CCl(4)-induced cirrhosis with ascites represents episodes of bacterial translocation. Hepatology 2006 44 : 633 9.
    • (2006) Hepatology , vol.44 , pp. 633-9
    • Guarner, C.1    Gonzalez-Navajas, J.M.2    Sanchez, E.3
  • 4
    • 2442666353 scopus 로고    scopus 로고
    • Bacterial DNA activates cell mediated immune response and nitric oxide overproduction in peritoneal macrophages from patients with cirrhosis and ascites
    • Frances R, Munoz C, Zapater P et al. Bacterial DNA activates cell mediated immune response and nitric oxide overproduction in peritoneal macrophages from patients with cirrhosis and ascites. Gut 2004 53 : 860 4.
    • (2004) Gut , vol.53 , pp. 860-4
    • Frances, R.1    Munoz, C.2    Zapater, P.3
  • 5
    • 12344273353 scopus 로고    scopus 로고
    • Intracellular cytokine expression in peritoneal monocyte/macrophages obtained from patients with cirrhosis and presence of bacterial DNA
    • Frances R, Rodriguez E, Munoz C et al. Intracellular cytokine expression in peritoneal monocyte/macrophages obtained from patients with cirrhosis and presence of bacterial DNA. Eur J Gastroenterol Hepatol 2005 17 : 45 51.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 45-51
    • Frances, R.1    Rodriguez, E.2    Munoz, C.3
  • 6
    • 35349013554 scopus 로고    scopus 로고
    • Soluble mediators engagement by bacterial DNA in cirrhotic patients with culture-negative ascitic fluid
    • Frances R, Gonzalez-Navajas JM, Zapater P et al. Soluble mediators engagement by bacterial DNA in cirrhotic patients with culture-negative ascitic fluid. Hepatology 2006 44 (Suppl. 1 461A.
    • (2006) Hepatology , vol.44 , Issue.SUPPL. 1
    • Frances, R.1    Gonzalez-Navajas, J.M.2    Zapater, P.3
  • 7
    • 2442745956 scopus 로고    scopus 로고
    • Spontaneous bacterial peritonitis
    • Such J, Runyon BA. Spontaneous bacterial peritonitis. Clin Infect Dis 1998 27 : 669 74.
    • (1998) Clin Infect Dis , vol.27 , pp. 669-74
    • Such, J.1    Runyon, B.A.2
  • 8
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000 408 : 740 5.
    • (2000) Nature , vol.408 , pp. 740-5
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3
  • 9
    • 0035003538 scopus 로고    scopus 로고
    • Toll meets bacterial CpG-DNA
    • Wagner H. Toll meets bacterial CpG-DNA. Immunity 2001 14 : 499 502.
    • (2001) Immunity , vol.14 , pp. 499-502
    • Wagner, H.1
  • 11
    • 31844433093 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 9 by DNA from different bacterial species
    • Dalpke A, Frank J, Peter M, Heeg K. Activation of Toll-like receptor 9 by DNA from different bacterial species. Infect Immun 2006 74 : 940 6.
    • (2006) Infect Immun , vol.74 , pp. 940-6
    • Dalpke, A.1    Frank, J.2    Peter, M.3    Heeg, K.4
  • 12
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg AM, Yi AK, Matson S et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995 374 : 546 9.
    • (1995) Nature , vol.374 , pp. 546-9
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 13
    • 0035979192 scopus 로고    scopus 로고
    • Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
    • Bauer S, Kirschning CJ, Hacker H et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA 2001 98 : 9237 42.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9237-42
    • Bauer, S.1    Kirschning, C.J.2    Hacker, H.3
  • 14
    • 0034755537 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, interleukin-6, and nitric oxide in sterile ascitic fluid and serum from patients with cirrhosis who subsequently develop ascitic fluid infection
    • Such J, Hillebrand DJ, Guarner C et al. Tumor necrosis factor-alpha, interleukin-6, and nitric oxide in sterile ascitic fluid and serum from patients with cirrhosis who subsequently develop ascitic fluid infection. Dig Dis Sci 2001 46 : 2360 6.
    • (2001) Dig Dis Sci , vol.46 , pp. 2360-6
    • Such, J.1    Hillebrand, D.J.2    Guarner, C.3
  • 15
    • 0031980857 scopus 로고    scopus 로고
    • Tumor necrosis factor and interleukin-6 in spontaneous bacterial peritonitis in cirrhosis: Relationship with the development of renal impairment and mortality
    • Navasa M, Follo A, Filella X et al. Tumor necrosis factor and interleukin-6 in spontaneous bacterial peritonitis in cirrhosis: relationship with the development of renal impairment and mortality. Hepatology 1998 27 : 1227 32.
    • (1998) Hepatology , vol.27 , pp. 1227-32
    • Navasa, M.1    Follo, A.2    Filella, X.3
  • 16
    • 0028956216 scopus 로고
    • Tumor necrosis factor alpha: A major contributor to the hyperdynamic circulation in prehepatic portal-hypertensive rats
    • Lopez-Talavera JC, Merrill WW, Groszmann RJ. Tumor necrosis factor alpha: a major contributor to the hyperdynamic circulation in prehepatic portal-hypertensive rats. Gastroenterology 1995 108 : 761 7.
    • (1995) Gastroenterology , vol.108 , pp. 761-7
    • Lopez-Talavera, J.C.1    Merrill, W.W.2    Groszmann, R.J.3
  • 17
    • 34047184756 scopus 로고    scopus 로고
    • Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites
    • Frances R, Chiva M, Sanchez E et al. Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites. J Hepatol 2007 46 : 797 803.
    • (2007) J Hepatol , vol.46 , pp. 797-803
    • Frances, R.1    Chiva, M.2    Sanchez, E.3
  • 18
    • 34548512841 scopus 로고    scopus 로고
    • Ascitic and serum bacterial DNA is a short-term survival indicator in patients with cirrhosis and culture-negative, non-neutrocytic ascites.
    • Zapater P, Frances R, Gonzalez-Navajas JM et al. Ascitic and serum bacterial DNA is a short-term survival indicator in patients with cirrhosis and culture-negative, non-neutrocytic ascites. Gastroenterol Hepatol 2006 29 (Suppl. 1 117.
    • (2006) Gastroenterol Hepatol , vol.29 , Issue.SUPPL. 1 , pp. 117
    • Zapater, P.1    Frances, R.2    Gonzalez-Navajas, J.M.3
  • 19
    • 0025099442 scopus 로고
    • Ascitic fluid polymorphonuclear cell count and serum to ascites albumin gradient in the diagnosis of bacterial peritonitis
    • Albillos A, Cuervas-Mons V, Millan I et al. Ascitic fluid polymorphonuclear cell count and serum to ascites albumin gradient in the diagnosis of bacterial peritonitis. Gastroenterology 1990 98 : 134 40.
    • (1990) Gastroenterology , vol.98 , pp. 134-40
    • Albillos, A.1    Cuervas-Mons, V.2    Millan, I.3
  • 20
    • 0028893025 scopus 로고
    • The natural history of the systemic inflammatory response syndrome (SIRS). a prospective study
    • Rangel-Frausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel RP. The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 1995 273 : 117 23.
    • (1995) JAMA , vol.273 , pp. 117-23
    • Rangel-Frausto, M.S.1    Pittet, D.2    Costigan, M.3    Hwang, T.4    Davis, C.S.5    Wenzel, R.P.6
  • 21
    • 0023004134 scopus 로고
    • Paracentesis of ascitic fluid. a safe procedure
    • Runyon BA. Paracentesis of ascitic fluid. A safe procedure. Arch Intern Med 1986 146 : 2259 61.
    • (1986) Arch Intern Med , vol.146 , pp. 2259-61
    • Runyon, B.A.1
  • 23
    • 0024999256 scopus 로고
    • Optimization of detection of bacterial endotoxin in plasma with the Limulus test
    • Roth RI, Levin FC, Levin J. Optimization of detection of bacterial endotoxin in plasma with the Limulus test. J Lab Clin Med 1990 116 : 153 61.
    • (1990) J Lab Clin Med , vol.116 , pp. 153-61
    • Roth, R.I.1    Levin, F.C.2    Levin, J.3
  • 24
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002 20 : 709 60.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-60
    • Krieg, A.M.1
  • 25
    • 0033390212 scopus 로고    scopus 로고
    • Signal transduction pathways activated by CpG-DNA
    • Hacker H. Signal transduction pathways activated by CpG-DNA. Curr Top Microbiol Immunol 2000 247 : 77 92.
    • (2000) Curr Top Microbiol Immunol , vol.247 , pp. 77-92
    • Hacker, H.1
  • 26
    • 0033215423 scopus 로고    scopus 로고
    • Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T cells to induce IFN-gamma production in vitro
    • Iho S, Yamamoto T, Takahashi T, Yamamoto S. Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T cells to induce IFN-gamma production in vitro. J Immunol 1999 163 : 3642 52.
    • (1999) J Immunol , vol.163 , pp. 3642-52
    • Iho, S.1    Yamamoto, T.2    Takahashi, T.3    Yamamoto, S.4
  • 27
    • 0031460777 scopus 로고    scopus 로고
    • Immunostimulatory DNA: Sequence-dependent production of potentially harmful or useful cytokines
    • Lipford GB, Sparwasser T, Bauer M et al. Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines. Eur J Immunol 1997 27 : 3420 6.
    • (1997) Eur J Immunol , vol.27 , pp. 3420-6
    • Lipford, G.B.1    Sparwasser, T.2    Bauer, M.3
  • 28
    • 0030816325 scopus 로고    scopus 로고
    • Macrophages sense pathogens via DNA motifs: Induction of tumor necrosis factor-alpha-mediated shock
    • Sparwasser T, Miethke T, Lipford G et al. Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock. Eur J Immunol 1997 27 : 1671 9.
    • (1997) Eur J Immunol , vol.27 , pp. 1671-9
    • Sparwasser, T.1    Miethke, T.2    Lipford, G.3
  • 29
    • 0029934754 scopus 로고    scopus 로고
    • Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
    • Cowdery JS, Chace JH, Yi AK, Krieg AM. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J Immunol 1996 156 : 4570 5.
    • (1996) J Immunol , vol.156 , pp. 4570-5
    • Cowdery, J.S.1    Chace, J.H.2    Yi, A.K.3    Krieg, A.M.4
  • 30
    • 0032775793 scopus 로고    scopus 로고
    • Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences
    • Martin-Orozco E, Kobayashi H, Van Uden J, Nguyen MD, Kornbluth RS, Raz E. Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences. Int Immunol 1999 11 : 1111 18.
    • (1999) Int Immunol , vol.11 , pp. 1111-18
    • Martin-Orozco, E.1    Kobayashi, H.2    Van Uden, J.3    Nguyen, M.D.4    Kornbluth, R.S.5    Raz, E.6
  • 31
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser T, Koch ES, Vabulas RM et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol 1998 28 : 2045 54.
    • (1998) Eur J Immunol , vol.28 , pp. 2045-54
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3
  • 32
    • 0036139042 scopus 로고    scopus 로고
    • Bacterial infections in cirrhosis: Epidemiological changes with invasive procedures and norfloxacin prophylaxis
    • Fernandez J, Navasa M, Gomez J et al. Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. Hepatology 2002 35 : 140 8.
    • (2002) Hepatology , vol.35 , pp. 140-8
    • Fernandez, J.1    Navasa, M.2    Gomez, J.3
  • 33
    • 0027438813 scopus 로고
    • Increased serum nitrite and nitrate levels in patients with cirrhosis: Relationship to endotoxemia
    • Guarner C, Soriano G, Tomas A et al. Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia. Hepatology 1993 18 : 1139 43.
    • (1993) Hepatology , vol.18 , pp. 1139-43
    • Guarner, C.1    Soriano, G.2    Tomas, A.3
  • 34
    • 0038717560 scopus 로고    scopus 로고
    • CpG motifs: The active ingredient in bacterial extracts?
    • Krieg AM. CpG motifs: the active ingredient in bacterial extracts? Nat Med 2003 9 : 831 5.
    • (2003) Nat Med , vol.9 , pp. 831-5
    • Krieg, A.M.1
  • 35
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
    • Chu RS, Targoni OS, Krieg AM, Lehmann PV, Harding CV. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J Exp Med 1997 186 : 1623 31.
    • (1997) J Exp Med , vol.186 , pp. 1623-31
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 36
    • 0030764558 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants
    • Roman M, Martin-Orozco E, Goodman JS et al. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat Med 1997 3 : 849 54.
    • (1997) Nat Med , vol.3 , pp. 849-54
    • Roman, M.1    Martin-Orozco, E.2    Goodman, J.S.3
  • 37
    • 0030850462 scopus 로고    scopus 로고
    • CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants
    • Lipford GB, Bauer M, Blank C, Reiter R, Wagner H, Heeg K. CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur J Immunol 1997 27 : 2340 4.
    • (1997) Eur J Immunol , vol.27 , pp. 2340-4
    • Lipford, G.B.1    Bauer, M.2    Blank, C.3    Reiter, R.4    Wagner, H.5    Heeg, K.6
  • 38
    • 0034667770 scopus 로고    scopus 로고
    • Phosphorothioate backbone modification modulates macrophage activation by CpG DNA
    • Sester DP, Naik S, Beasley SJ, Hume DA, Stacey KJ. Phosphorothioate backbone modification modulates macrophage activation by CpG DNA. J Immunol 2000 165 : 4165 73.
    • (2000) J Immunol , vol.165 , pp. 4165-73
    • Sester, D.P.1    Naik, S.2    Beasley, S.J.3    Hume, D.A.4    Stacey, K.J.5
  • 39
    • 24744452821 scopus 로고    scopus 로고
    • Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides
    • Roberts TL, Dunn JA, Terry TD et al. Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides. J Immunol 2005 175 : 3569 76.
    • (2005) J Immunol , vol.175 , pp. 3569-76
    • Roberts, T.L.1    Dunn, J.A.2    Terry, T.D.3
  • 40
    • 0010528829 scopus 로고    scopus 로고
    • Cutting edge: Bacterial DNA and LPS act in synergy in inducing nitric oxide production in RAW 264·7 macrophages
    • Gao JJ, Zuvanich EG, Xue Q, Horn DL, Silverstein R, Morrison DC. Cutting edge: bacterial DNA and LPS act in synergy in inducing nitric oxide production in RAW 264·7 macrophages. J Immunol 1999 163 : 4095 9.
    • (1999) J Immunol , vol.163 , pp. 4095-9
    • Gao, J.J.1    Zuvanich, E.G.2    Xue, Q.3    Horn, D.L.4    Silverstein, R.5    Morrison, D.C.6
  • 41
    • 34250202565 scopus 로고    scopus 로고
    • Bacterial DNA induces the complement system activation in serum and ascitic fluid from patients with advanced cirrhosis
    • Frances R, Gonzalez-Navajas JM, Zapater P et al. Bacterial DNA induces the complement system activation in serum and ascitic fluid from patients with advanced cirrhosis. J Clin Immunol 2007 27 : 438 44.
    • (2007) J Clin Immunol , vol.27 , pp. 438-44
    • Frances, R.1    Gonzalez-Navajas, J.M.2    Zapater, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.