메뉴 건너뛰기




Volumn 4, Issue 4, 2007, Pages 188-197

The effect of palifermin on chemotherapy- and radiation therapy-induced mucositis: A review of the current literature

Author keywords

Autologous stem cell transplantation; Hematopoietic stem cell transplantation; Recombinant human keratinocyte growth factor

Indexed keywords

BUSULFAN; CISPLATIN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; KERATINOCYTE GROWTH FACTOR; METHOTREXATE; MORPHINE; PALIFERMIN; TACROLIMUS;

EID: 35349012312     PISSN: 15432912     EISSN: None     Source Type: Journal    
DOI: 10.3816/SCT.2007.n.014     Document Type: Review
Times cited : (24)

References (58)
  • 1
    • 10344242939 scopus 로고    scopus 로고
    • Palifermin for oral mucositis after intensive therapy for hematologic cancers
    • Spielberger R, Stiff P, Bensinger W, et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med 2004; 351:2590-2598.
    • (2004) N Engl J Med , vol.351 , pp. 2590-2598
    • Spielberger, R.1    Stiff, P.2    Bensinger, W.3
  • 2
    • 0033952344 scopus 로고    scopus 로고
    • Patient reports of complications of bone marrow transplantation
    • Bellm LA, Epstein JB, Rose-Ped A, et al. Patient reports of complications of bone marrow transplantation. Support Care Cancer 2000; 8:33-39.
    • (2000) Support Care Cancer , vol.8 , pp. 33-39
    • Bellm, L.A.1    Epstein, J.B.2    Rose-Ped, A.3
  • 3
    • 0035870833 scopus 로고    scopus 로고
    • Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation
    • Sonis ST, Oster G, Fuchs H, et al. Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 2001; 19:2201-2205.
    • (2001) J Clin Oncol , vol.19 , pp. 2201-2205
    • Sonis, S.T.1    Oster, G.2    Fuchs, H.3
  • 4
    • 0032795655 scopus 로고    scopus 로고
    • Analysis of factors that correlate with mucositis in recipients of autologous and allogeneic stem-cell transplants
    • Rapoport AP, Miller Watelet LF, Linder T, et al. Analysis of factors that correlate with mucositis in recipients of autologous and allogeneic stem-cell transplants. J Clin Oncol 1999; 17:2446-2453.
    • (1999) J Clin Oncol , vol.17 , pp. 2446-2453
    • Rapoport, A.P.1    Miller Watelet, L.F.2    Linder, T.3
  • 5
    • 20544432888 scopus 로고    scopus 로고
    • Comparison of plain ice and flavoured ice for preventing oral mucositis associated with the use of 5 fluorouracil
    • Nikoletti S, Hyde S, Shaw T, et al. Comparison of plain ice and flavoured ice for preventing oral mucositis associated with the use of 5 fluorouracil. J Clin Nurs 2005; 14:750-753.
    • (2005) J Clin Nurs , vol.14 , pp. 750-753
    • Nikoletti, S.1    Hyde, S.2    Shaw, T.3
  • 6
    • 0037854684 scopus 로고    scopus 로고
    • Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: A randomized, placebo-controlled trial
    • Nottage M, McLachlan SA, Brittain MA, et al. Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: a randomized, placebo-controlled trial. Support Care Cancer 2003; 11:41-47.
    • (2003) Support Care Cancer , vol.11 , pp. 41-47
    • Nottage, M.1    McLachlan, S.A.2    Brittain, M.A.3
  • 7
    • 28744455216 scopus 로고    scopus 로고
    • Cytoprotection by amifostine during autologous stem cell transplantation for advanced refractory hematologic malignancies
    • Gabriel DA, Shea TC, Serody JS, et al. Cytoprotection by amifostine during autologous stem cell transplantation for advanced refractory hematologic malignancies. Biol Blood Marrow Transplant 2005; 11:1022-1030.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 1022-1030
    • Gabriel, D.A.1    Shea, T.C.2    Serody, J.S.3
  • 8
    • 0033506548 scopus 로고    scopus 로고
    • Reduction of oral mucositis by filgrastim (r-metHuG-CSF) in patients receiving chemotherapy
    • Crawford J, Tomita DK, Mazanet R, et al. Reduction of oral mucositis by filgrastim (r-metHuG-CSF) in patients receiving chemotherapy. Cytokines Cell Mol Ther 1999; 5:187-193.
    • (1999) Cytokines Cell Mol Ther , vol.5 , pp. 187-193
    • Crawford, J.1    Tomita, D.K.2    Mazanet, R.3
  • 9
    • 85047699364 scopus 로고    scopus 로고
    • Mouth-washings with recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF) do not improve grade III-IV oropharyngeal mucositis (OM) in patients with hematological malignancies undergoing stem cell transplantation. Results of a randomized double-blind placebo-controlled study
    • Valcarcel D, Sanz MA, Jr, Sureda A, et al. Mouth-washings with recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF) do not improve grade III-IV oropharyngeal mucositis (OM) in patients with hematological malignancies undergoing stem cell transplantation. Results of a randomized double-blind placebo-controlled study. Bone Marrow Transplant 2002; 29:783-787.
    • (2002) Bone Marrow Transplant , vol.29 , pp. 783-787
    • Valcarcel, D.1    Sanz Jr, M.A.2    Sureda, A.3
  • 10
    • 23844546931 scopus 로고    scopus 로고
    • Therapeutic efficacy by recombinant human granulocyte/monocyte-colony stimulating factor on mucositis occurring in patients with oral and oropharynx tumors treated with curative radiotherapy: A multicenter open randomized phase III study
    • Masucci G, Broman P, Kelly C, et al. Therapeutic efficacy by recombinant human granulocyte/monocyte-colony stimulating factor on mucositis occurring in patients with oral and oropharynx tumors treated with curative radiotherapy: a multicenter open randomized phase III study. Med Oncol 2005; 22:247-256.
    • (2005) Med Oncol , vol.22 , pp. 247-256
    • Masucci, G.1    Broman, P.2    Kelly, C.3
  • 11
    • 5144229908 scopus 로고    scopus 로고
    • A biological approach to mucositis
    • discussion 5-6
    • Sonis ST. A biological approach to mucositis. J Support Oncol 2004; 2:21-32; discussion 5-6.
    • (2004) J Support Oncol , vol.2 , pp. 21-32
    • Sonis, S.T.1
  • 12
    • 0001088219 scopus 로고
    • Purification and characterization of a newly identified growth factor specific for epithelial cells
    • Rubin JS, Osada H, Finch PW, et al. Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A 1989; 86:802-806.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 802-806
    • Rubin, J.S.1    Osada, H.2    Finch, P.W.3
  • 13
    • 0024324070 scopus 로고
    • Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth
    • Finch PW, Rubin JS, Miki T, et al. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 1989; 245:752-755.
    • (1989) Science , vol.245 , pp. 752-755
    • Finch, P.W.1    Rubin, J.S.2    Miki, T.3
  • 14
    • 85030580255 scopus 로고    scopus 로고
    • Kepivance® [package insert, Thousand Oaks, CA: Amgen Inc; 2005
    • Kepivance® [package insert]. Thousand Oaks, CA: Amgen Inc; 2005.
  • 15
    • 0036318224 scopus 로고    scopus 로고
    • Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
    • Braun S, Hanselmann C, Gassmann MG, et al. Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol 2002; 22:5492-5505.
    • (2002) Mol Cell Biol , vol.22 , pp. 5492-5505
    • Braun, S.1    Hanselmann, C.2    Gassmann, M.G.3
  • 16
    • 0032112981 scopus 로고    scopus 로고
    • Production of recombinant human ketatinocyte growth factor in Escherichia coli cells [in Russian]
    • Ptitsyn LR, Al'tman IB, Gurov MV, et al. Production of recombinant human ketatinocyte growth factor in Escherichia coli cells [in Russian]. Bioorg Khim 1998; 24:523-529.
    • (1998) Bioorg Khim , vol.24 , pp. 523-529
    • Ptitsyn, L.R.1    Al'tman, I.B.2    Gurov, M.V.3
  • 17
    • 34447303546 scopus 로고    scopus 로고
    • Palifermin (recombinant keratinocyte growth factor-1): A pleiotropic growth factor with multiple biological activities in preventing chemotherapy- and radiotherapy-induced mucositis
    • Blijlevens N, Sonis S. Palifermin (recombinant keratinocyte growth factor-1): a pleiotropic growth factor with multiple biological activities in preventing chemotherapy- and radiotherapy-induced mucositis. Ann Oncol 2007; 18:817-826.
    • (2007) Ann Oncol , vol.18 , pp. 817-826
    • Blijlevens, N.1    Sonis, S.2
  • 18
    • 0036371859 scopus 로고    scopus 로고
    • Cell kinetic studies in the murine ventral tongue epithelium: Mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF)
    • Potten CS, Booth D, Cragg NJ, et al. Cell kinetic studies in the murine ventral tongue epithelium: mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF). Cell Prolif 2002; 35(suppl 1):32-47.
    • (2002) Cell Prolif , vol.35 , Issue.SUPPL. 1 , pp. 32-47
    • Potten, C.S.1    Booth, D.2    Cragg, N.J.3
  • 19
    • 0942289878 scopus 로고    scopus 로고
    • Cellular kinetics of murine lung: Model system to determine basis for radioprotection with keratinocyte growth factor
    • Terry NH, Brinkley J, Doig AJ, et al. Cellular kinetics of murine lung: model system to determine basis for radioprotection with keratinocyte growth factor. Int J Radiat Oncol Biol Phys 2004; 58:435-444.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 435-444
    • Terry, N.H.1    Brinkley, J.2    Doig, A.J.3
  • 20
    • 33744779624 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety assessment of palifermin (rHuKGF) in healthy volunteers
    • Zia-Amirhosseini P, Salfi M, Leese P, et al. Pharmacokinetics, pharmacodynamics, and safety assessment of palifermin (rHuKGF) in healthy volunteers. Clin Pharmacol Ther 2006; 79:558-569.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 558-569
    • Zia-Amirhosseini, P.1    Salfi, M.2    Leese, P.3
  • 21
    • 0034076350 scopus 로고    scopus 로고
    • KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT
    • Panoskaltsis-Mortari A, Ingbar DH, Jung P, et al. KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT. Am J Physiol Lung Cell Mol Physiol 2000; 278:L988-L999.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Panoskaltsis-Mortari, A.1    Ingbar, D.H.2    Jung, P.3
  • 22
    • 0037609493 scopus 로고    scopus 로고
    • Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia
    • Ray P, Devaux Y, Stolz DB, et al. Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia. Proc Natl Acad Sci U S A 2003; 100:6098-6103.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6098-6103
    • Ray, P.1    Devaux, Y.2    Stolz, D.B.3
  • 23
    • 30844448578 scopus 로고    scopus 로고
    • KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells
    • Chang Y, Wang J, Lu X, et al. KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells. J Lipid Res 2005; 46:2624-2635.
    • (2005) J Lipid Res , vol.46 , pp. 2624-2635
    • Chang, Y.1    Wang, J.2    Lu, X.3
  • 24
    • 11144310601 scopus 로고    scopus 로고
    • Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells
    • Bao S, Wang Y, Sweeney P, et al. Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 2005; 288:L36-L42.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Bao, S.1    Wang, Y.2    Sweeney, P.3
  • 25
    • 0030785751 scopus 로고    scopus 로고
    • KGF facilitates repair of radiation-induced DNA damage in alveolar epithelial cells
    • Takeoka M, Ward WF, Pollack H, et al. KGF facilitates repair of radiation-induced DNA damage in alveolar epithelial cells. Am J Physiol 1997; 272(6 part 1):L1174-L1180.
    • (1997) Am J Physiol , vol.272 , Issue.6 PART 1
    • Takeoka, M.1    Ward, W.F.2    Pollack, H.3
  • 26
    • 85030577255 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of 2 dosing regimens of palifermin in patients with hematologic malignancies undergoing high-dose chemoradiotherapy and hematopoietic stem cell transplantation
    • Abstract
    • Zia-Amirhosseini P, Salfi M, Elhardt D, et al. Pharmacokinetics (PK) of 2 dosing regimens of palifermin in patients with hematologic malignancies undergoing high-dose chemoradiotherapy and hematopoietic stem cell transplantation. Blood 2005; 106:1256a (Abstract #5294).
    • (2005) Blood , vol.106 , Issue.5294
    • Zia-Amirhosseini, P.1    Salfi, M.2    Elhardt, D.3
  • 27
    • 33750725398 scopus 로고    scopus 로고
    • Effect of renal function on the pharmacokinetics of palifermin
    • Gillespie B, Zia-Amirhosseini P, Salfi M, et al. Effect of renal function on the pharmacokinetics of palifermin. J Clin Pharmacol 2006; 46:1460-1468.
    • (2006) J Clin Pharmacol , vol.46 , pp. 1460-1468
    • Gillespie, B.1    Zia-Amirhosseini, P.2    Salfi, M.3
  • 28
    • 33846668768 scopus 로고    scopus 로고
    • Palifermin reduces the incidence of oral mucositis in patients with metastatic colorectal cancer treated with fluorouracil-based chemotherapy
    • Rosen LS, Abdi E, Davis ID, et al. Palifermin reduces the incidence of oral mucositis in patients with metastatic colorectal cancer treated with fluorouracil-based chemotherapy. J Clin Oncol 2006; 24:5194-5200.
    • (2006) J Clin Oncol , vol.24 , pp. 5194-5200
    • Rosen, L.S.1    Abdi, E.2    Davis, I.D.3
  • 29
    • 4344593885 scopus 로고    scopus 로고
    • Phase 2 study of recombinant human keratinocyte growth factor in head & neck cancer treated with standard or hyperfractionated irradiation & concurrent chemotherapy
    • Abstract
    • Brizel DM, Le QT, Rosenthal D, et al. Phase 2 study of recombinant human keratinocyte growth factor in head & neck cancer treated with standard or hyperfractionated irradiation & concurrent chemotherapy. Int J Radiat Oncol Biol Phys 2002; 54:285-286 (Abstract #2128).
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , Issue.2128 , pp. 285-286
    • Brizel, D.M.1    Le, Q.T.2    Rosenthal, D.3
  • 30
    • 3042737129 scopus 로고    scopus 로고
    • A phase I/II trial of escalating doses of recombinant human keratinocyte growth factor in head & neck cancer patients receiving radiotherapy with concurrent chemotherapy
    • Abstract
    • Brizel DM, Herman T, Goffinet D, et al. A phase I/II trial of escalating doses of recombinant human keratinocyte growth factor in head & neck cancer patients receiving radiotherapy with concurrent chemotherapy. Int J Radiat Oncol Biol Phys 2001; 51:40 (Abstract #67).
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , Issue.67 , pp. 40
    • Brizel, D.M.1    Herman, T.2    Goffinet, D.3
  • 31
    • 0037842184 scopus 로고    scopus 로고
    • Randomized phase I trial of recombinant human keratinocyte growth factor plus chemotherapy: Potential role as mucosal protectant
    • Meropol NJ, Somer RA, Gutheil J, et al. Randomized phase I trial of recombinant human keratinocyte growth factor plus chemotherapy: potential role as mucosal protectant. J Clin Oncol 2003; 21:1452-1458.
    • (2003) J Clin Oncol , vol.21 , pp. 1452-1458
    • Meropol, N.J.1    Somer, R.A.2    Gutheil, J.3
  • 32
    • 33751194102 scopus 로고    scopus 로고
    • Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT)
    • Blazar BR, Weisdorf DJ, Defor T, et al. Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT). Blood 2006; 108:3216-3222.
    • (2006) Blood , vol.108 , pp. 3216-3222
    • Blazar, B.R.1    Weisdorf, D.J.2    Defor, T.3
  • 33
    • 85030582759 scopus 로고    scopus 로고
    • Evaluation of single-dose palifermin to reduce oral mucositis in fractionated total body irradiation and high dose chemotherapy with autologous peripheral blood progenitor cell transplantation
    • Abstract
    • Shea TC, Kewalramani T, Mun Y, et al. Evaluation of single-dose palifermin to reduce oral mucositis in fractionated total body irradiation and high dose chemotherapy with autologous peripheral blood progenitor cell transplantation. Blood 2006; 108:875a (Abstract #3073).
    • (2006) Blood , vol.108 , Issue.3073
    • Shea, T.C.1    Kewalramani, T.2    Mun, Y.3
  • 34
    • 18744392950 scopus 로고    scopus 로고
    • Keratinocyte growth factor factor (palifermin) in combination with tacrolimus and methotrexate for the prevention of acute graft-vs-host disease in patients at high risk of aGVHD
    • Abstract
    • Reynolds CM, Levine JE, Uberti JP, et al. Keratinocyte growth factor factor (palifermin) in combination with tacrolimus and methotrexate for the prevention of acute graft-vs-host disease in patients at high risk of aGVHD. Blood 2004; 104:343a (Abstract #1228).
    • (2004) Blood , vol.104 , Issue.1228
    • Reynolds, C.M.1    Levine, J.E.2    Uberti, J.P.3
  • 35
    • 1042280099 scopus 로고    scopus 로고
    • Efficacy of recombinant human keratinocyte growth factor in reducing mucositis in patients with hematologic malignancies undergoing autologous peripheral blood progenitor cell transplantation after radiation-based conditioning - results of a phase 2 trial
    • Abstract
    • Spielberger R, Stiff P, Emmanouilides C, et al. Efficacy of recombinant human keratinocyte growth factor in reducing mucositis in patients with hematologic malignancies undergoing autologous peripheral blood progenitor cell transplantation after radiation-based conditioning - results of a phase 2 trial. Proc Am Soc Clin Oncol 2001; 20:3 (Abstract #25).
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.25 , pp. 3
    • Spielberger, R.1    Stiff, P.2    Emmanouilides, C.3
  • 36
    • 32844454915 scopus 로고    scopus 로고
    • Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT)
    • Stiff PJ, Erder H, Bensinger WI, et al. Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT). Bone Marrow Transplant 2006; 37:393-401.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 393-401
    • Stiff, P.J.1    Erder, H.2    Bensinger, W.I.3
  • 37
    • 33751161936 scopus 로고    scopus 로고
    • Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting
    • Stiff PJ, Emmanouilides C, Bensinger WI, et al. Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting. J Clin Oncol 2006; 24:5186-5193.
    • (2006) J Clin Oncol , vol.24 , pp. 5186-5193
    • Stiff, P.J.1    Emmanouilides, C.2    Bensinger, W.I.3
  • 38
    • 0033566285 scopus 로고    scopus 로고
    • Keratinocyte growth factor separates graft-versus-leukemia effects from graft-versus-host disease
    • Krijanovski OI, Hill GR, Cooke KR, et al. Keratinocyte growth factor separates graft-versus-leukemia effects from graft-versus-host disease. Blood 1999; 94:825-831.
    • (1999) Blood , vol.94 , pp. 825-831
    • Krijanovski, O.I.1    Hill, G.R.2    Cooke, K.R.3
  • 39
    • 27844494816 scopus 로고    scopus 로고
    • Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model
    • Vanclee A, Lutgens LC, Oving EB, et al. Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model. Bone Marrow Transplant 2005; 36:907-915.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 907-915
    • Vanclee, A.1    Lutgens, L.C.2    Oving, E.B.3
  • 40
    • 0034672365 scopus 로고    scopus 로고
    • Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury
    • Panoskaltsis-Mortari A, Taylor PA, Rubin JS, et al. Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury. Blood 2000; 96:4350-4356.
    • (2000) Blood , vol.96 , pp. 4350-4356
    • Panoskaltsis-Mortari, A.1    Taylor, P.A.2    Rubin, J.S.3
  • 41
    • 0037100314 scopus 로고    scopus 로고
    • Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease
    • Rossi S, Blazar BR, Farrell CL, et al. Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease. Blood 2002; 100:682-691.
    • (2002) Blood , vol.100 , pp. 682-691
    • Rossi, S.1    Blazar, B.R.2    Farrell, C.L.3
  • 42
    • 0037097583 scopus 로고    scopus 로고
    • Protection from thymic epithelial cell injury by keratinocyte growth factor: A new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation
    • Min D, Taylor PA, Panoskaltsis-Mortari A, et al. Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation. Blood 2002; 99:4592-4600.
    • (2002) Blood , vol.99 , pp. 4592-4600
    • Min, D.1    Taylor, P.A.2    Panoskaltsis-Mortari, A.3
  • 43
    • 34347400589 scopus 로고    scopus 로고
    • Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques
    • Seggewiss R, Lore K, Guenaga FJ, et al. Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques. Blood 2007; 110:441-449.
    • (2007) Blood , vol.110 , pp. 441-449
    • Seggewiss, R.1    Lore, K.2    Guenaga, F.J.3
  • 44
    • 35348964942 scopus 로고    scopus 로고
    • The significance of palifermin (Kepivance) in reduction of oral mucositis incidence and acute graft versus host disease in patients with hematological diseases undergoing HSCT
    • Nasilowska-Adamska B, Rzepecki P, Manko J, et al. The significance of palifermin (Kepivance) in reduction of oral mucositis incidence and acute graft versus host disease in patients with hematological diseases undergoing HSCT. Bone Marrow Transplant 2006; 13:77-78B.
    • (2006) Bone Marrow Transplant , vol.13
    • Nasilowska-Adamska, B.1    Rzepecki, P.2    Manko, J.3
  • 45
    • 0030960998 scopus 로고    scopus 로고
    • Cytokine cascades in acute graft-versus-host disease
    • Krenger W, Hill GR, Ferrara JL. Cytokine cascades in acute graft-versus-host disease. Transplantation 1997; 64:553-558.
    • (1997) Transplantation , vol.64 , pp. 553-558
    • Krenger, W.1    Hill, G.R.2    Ferrara, J.L.3
  • 46
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines
    • Hill GR, Crawford JM, Cooke KR, et al. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997; 90:3204-3213.
    • (1997) Blood , vol.90 , pp. 3204-3213
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3
  • 47
    • 33644524067 scopus 로고    scopus 로고
    • French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: Results at 2 years (FNCLCC-GORTEC)
    • Bensadoun RJ, Benezery K, Dassonville O, et al. French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: results at 2 years (FNCLCC-GORTEC). Int J Radiat Oncol Biol Phys 2006; 64:983-994.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 983-994
    • Bensadoun, R.J.1    Benezery, K.2    Dassonville, O.3
  • 48
    • 16644378853 scopus 로고    scopus 로고
    • Influence of keratinocyte growth factor on clonal growth of epithelial tumor cells, lymphoma and leukemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro
    • Oelmann E, Haghgu S, Kulimova E, et al. Influence of keratinocyte growth factor on clonal growth of epithelial tumor cells, lymphoma and leukemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro. Int J Oncol 2004; 25:1001-1012.
    • (2004) Int J Oncol , vol.25 , pp. 1001-1012
    • Oelmann, E.1    Haghgu, S.2    Kulimova, E.3
  • 49
    • 0033011048 scopus 로고    scopus 로고
    • FGF7/KGF triggers cell transformation and invasion on immortalised human prostatic epithelial PNT1A cells
    • Ropiquet F, Huguenin S, Villette JM, et al. FGF7/KGF triggers cell transformation and invasion on immortalised human prostatic epithelial PNT1A cells. Int J Cancer 1999; 82:237-243.
    • (1999) Int J Cancer , vol.82 , pp. 237-243
    • Ropiquet, F.1    Huguenin, S.2    Villette, J.M.3
  • 50
    • 0034793549 scopus 로고    scopus 로고
    • Keratinocyte growth factor-induced motility of breast cancer cells
    • Zang XP, Pento JT. Keratinocyte growth factor-induced motility of breast cancer cells. Clin Exp Metastasis 2000; 18:573-580.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 573-580
    • Zang, X.P.1    Pento, J.T.2
  • 51
    • 0036417339 scopus 로고    scopus 로고
    • Keratinocyte growth factor stimulates the migration and proliferation of breast cancer cells in a culture wounding model
    • Nguyen TN, Zang XP, Pento JT. Keratinocyte growth factor stimulates the migration and proliferation of breast cancer cells in a culture wounding model. Pharmacol Res 2002; 46:179-183.
    • (2002) Pharmacol Res , vol.46 , pp. 179-183
    • Nguyen, T.N.1    Zang, X.P.2    Pento, J.T.3
  • 52
    • 0031964507 scopus 로고    scopus 로고
    • Effects of keratinocyte growth factor on the proliferation and radiation survival of human squamous cell carcinoma cell lines in vitro and in vivo
    • Ning S, Shui C, Khan WB, et al. Effects of keratinocyte growth factor on the proliferation and radiation survival of human squamous cell carcinoma cell lines in vitro and in vivo. Int J Radiat Oncol Biol Phys 1998; 40:177-187.
    • (1998) Int J Radiat Oncol Biol Phys , vol.40 , pp. 177-187
    • Ning, S.1    Shui, C.2    Khan, W.B.3
  • 53
    • 0037314968 scopus 로고    scopus 로고
    • Effect of keratinocyte growth factor on the proliferation, clonogenic capacity and colony size of human epithelial tumour cells in vitro
    • Hille A, Rave-Frank M, Pradier O, et al. Effect of keratinocyte growth factor on the proliferation, clonogenic capacity and colony size of human epithelial tumour cells in vitro. Int J Radiat Biol 2003; 79:119-128.
    • (2003) Int J Radiat Biol , vol.79 , pp. 119-128
    • Hille, A.1    Rave-Frank, M.2    Pradier, O.3
  • 54
    • 0242361792 scopus 로고    scopus 로고
    • Fibroblast growth factors (FGFS) increase breast tumor growth rate, metastases, blood flow and oxygenation without significant change in vascular density
    • Dunn JF, Swartz HM, eds, New York, NY: Kluwer Academic/Plenum Publishers;
    • Okunieff P, Fenton BM, Zhang L, et al. Fibroblast growth factors (FGFS) increase breast tumor growth rate, metastases, blood flow and oxygenation without significant change in vascular density. In: Dunn JF, Swartz HM, eds. Oxygen Transport to Tissue XXIV. New York, NY: Kluwer Academic/Plenum Publishers; 2003:593-601.
    • (2003) Oxygen Transport to Tissue XXIV , pp. 593-601
    • Okunieff, P.1    Fenton, B.M.2    Zhang, L.3
  • 55
    • 0036304310 scopus 로고    scopus 로고
    • The effect of keratinocyte growth factor on tumour growth and small intestinal mucositis after chemotherapy in the rat with breast cancer
    • Gibson RJ, Keefe DM, Clarke JM, et al. The effect of keratinocyte growth factor on tumour growth and small intestinal mucositis after chemotherapy in the rat with breast cancer. Cancer Chemother Pharmacol 2002; 50:53-58.
    • (2002) Cancer Chemother Pharmacol , vol.50 , pp. 53-58
    • Gibson, R.J.1    Keefe, D.M.2    Clarke, J.M.3
  • 56
    • 33750980657 scopus 로고    scopus 로고
    • Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer
    • Matsunobu T, Ishiwata T, Yoshino M, et al. Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer. Int J Oncol 2006; 28:307-314.
    • (2006) Int J Oncol , vol.28 , pp. 307-314
    • Matsunobu, T.1    Ishiwata, T.2    Yoshino, M.3
  • 57
    • 85030591549 scopus 로고    scopus 로고
    • Long-term survival is comparable between palifermin-treated and placebo-treated patients with hematologic malignancies undergoing high-dose chemotherapy and total body irradiation followed by autologous hematopoietic stem cell transplantation
    • Abstract
    • Spielberger R, Emmanouilides C, Bensinger W, et al. Long-term survival is comparable between palifermin-treated and placebo-treated patients with hematologic malignancies undergoing high-dose chemotherapy and total body irradiation followed by autologous hematopoietic stem cell transplantation. Blood 2005; 106:828a (Abstract #2925).
    • (2005) Blood , vol.106 , Issue.2925
    • Spielberger, R.1    Emmanouilides, C.2    Bensinger, W.3
  • 58
    • 0034798720 scopus 로고    scopus 로고
    • Keratinocyte growth factors radioprotect bowel and bone marrow but not KHT sarcoma
    • Okunieff P, Li M, Liu W, et al. Keratinocyte growth factors radioprotect bowel and bone marrow but not KHT sarcoma. Am J Clin Oncol 2001; 24:491-495.
    • (2001) Am J Clin Oncol , vol.24 , pp. 491-495
    • Okunieff, P.1    Li, M.2    Liu, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.