Contraceptive and hormonal properties of the stem bark of Dysoxylum binectariferum in rat and docking analysis of rohitukine, the alkaloid isolated from active chloroform soluble fraction

Contraception

Volumn 76, Issue 5, 2007, Pages 400-407

  Keshri, Govind ^a   Oberoi, Ravi Mohan ^a   Lakshmi, Vijai ^a   Pandey, Kartikay ^a   Singh, Man Mohan ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Alkaloid; Antiestrogenicity; Contraceptive; Docking analysis; Dysoxylum binectariferum; Early postimplantation; Estrogen receptor; Estrogenicity; Implantation; Rat; Rohitukine

Indexed keywords

ALCOHOL; ALKALOID; ANTIESTROGEN; ARGININE; ASPARTIC ACID; CHLOROFORM; DYSOXYLUM BINECTARIFERUM EXTRACT; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ETHINYLESTRADIOL; GLUTAMIC ACID; HISTIDINE; LIGAND; PHENOL DERIVATIVE; PLACEBO; PLANT EXTRACT; POSTCOITUS CONTRACEPTIVE AGENT; RALOXIFENE; ROHITUKINE; UNCLASSIFIED DRUG;

ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BARK; BINDING SITE; CHROMATOGRAPHY; COMPUTER PROGRAM; CONTRACEPTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG ISOLATION; DRUG RECEPTOR BINDING; DYSOXYLUM BINECTARIFERUM; ESTROGEN ACTIVITY; FEMALE; FRACTIONATION; GEOMETRY; HYDROPHOBICITY; IMPLANTATION; MEDICINAL PLANT; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; OVARIECTOMY; PREGNANCY TERMINATION; RAT; SINGLE DRUG DOSE; UTERINE CERVIX RIPENING; UTERUS WEIGHT; VAGINA EPITHELIUM;

ANIMALS; CONTRACEPTIVES, POSTCOITAL; EMBRYO IMPLANTATION; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; LIMONINS; MALE; MELIACEAE; MOLECULAR STRUCTURE; PLANT BARK; PLANT STEMS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35349000057     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2007.07.009     Document Type: Article

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