메뉴 건너뛰기




Volumn 9, Issue 5, 2007, Pages 375-382

Appropriate management of axial spondyloarthritis

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; CORTICOSTEROID; ETANERCEPT; INFLIXIMAB; LEFLUNOMIDE; METHOTREXATE; METHYLPREDNISOLONE; PAMIDRONIC ACID; PARACETAMOL; PLACEBO; SALAZOSULFAPYRIDINE; THALIDOMIDE;

EID: 35348982966     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-007-0060-8     Document Type: Review
Times cited : (10)

References (49)
  • 1
    • 0037129952 scopus 로고    scopus 로고
    • Update on spondyloarthropathies
    • Khan MA: Update on spondyloarthropathies. Ann Intern Med 2002, 136:896-907.
    • (2002) Ann Intern Med , vol.136 , pp. 896-907
    • Khan, M.A.1
  • 2
    • 33744945029 scopus 로고    scopus 로고
    • Assessments in ankylosing spondylitis
    • An excellent review of core sets of health domains used for monitoring AS in clinical practice and clinical trials. Discusses measures for assessing disease activity, functional status, and structural damage
    • Zochling J, Braun J, van der Heijde D: Assessments in ankylosing spondylitis. Best Pract Res Clin Rheumatol 2006, 20:521-537. An excellent review of core sets of health domains used for monitoring AS in clinical practice and clinical trials. Discusses measures for assessing disease activity, functional status, and structural damage.
    • (2006) Best Pract Res Clin Rheumatol , vol.20 , pp. 521-537
    • Zochling, J.1    Braun, J.2    van der Heijde, D.3
  • 3
    • 0034888069 scopus 로고    scopus 로고
    • Ankylosing spondylitis assessment group preliminary definition of short-term improvement in ankylosing spondylitis
    • Anderson JJ, Baron G, van der Heijde D, et al.: Ankylosing spondylitis assessment group preliminary definition of short-term improvement in ankylosing spondylitis. Arthritis Rheum 2001, 44:1876-1886.
    • (2001) Arthritis Rheum , vol.44 , pp. 1876-1886
    • Anderson, J.J.1    Baron, G.2    van der Heijde, D.3
  • 4
    • 0028579768 scopus 로고
    • A new approach to defining functional ability in ankylosing spondylitis: The development of the Bath Ankylosing Spondylitis Functional Index
    • Calin A, Garrett SL, Whitelock HC, et al.: A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol 1994, 21:2281-2285.
    • (1994) J Rheumatol , vol.21 , pp. 2281-2285
    • Calin, A.1    Garrett, S.L.2    Whitelock, H.C.3
  • 5
    • 0028575453 scopus 로고
    • New approach to defining disease status in ankylosing spondylitis: The Bath ankylosing spondylitis disease activity index
    • Garrett SL, Jenkinson T, Kennedy LG, et al.: New approach to defining disease status in ankylosing spondylitis: the Bath ankylosing spondylitis disease activity index. J Rheumatol 1994, 21:2286-2291.
    • (1994) J Rheumatol , vol.21 , pp. 2286-2291
    • Garrett, S.L.1    Jenkinson, T.2    Kennedy, L.G.3
  • 6
    • 0029937430 scopus 로고    scopus 로고
    • Group education for people with arthritis
    • Barlow JH, Barefoot J: Group education for people with arthritis. Pt Educat Counsel 1996, 27:257-267.
    • (1996) Pt Educat Counsel , vol.27 , pp. 257-267
    • Barlow, J.H.1    Barefoot, J.2
  • 8
    • 0034758237 scopus 로고    scopus 로고
    • Combined spa-exercise therapy is effective in patients with ankylosing spondylitis: A randomized controlled trial
    • van Tubergen A, Landewe R, van der Heijde D, et al.: Combined spa-exercise therapy is effective in patients with ankylosing spondylitis: A randomized controlled trial. Arthritis Rheum 2001, 45:430-438.
    • (2001) Arthritis Rheum , vol.45 , pp. 430-438
    • van Tubergen, A.1    Landewe, R.2    van der Heijde, D.3
  • 9
    • 33645124111 scopus 로고    scopus 로고
    • Zochling J, van der Heijde D, Burgos-Vargas R, et al.: ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2006, 65:442-452. The authors present 10 key evidence-based recommendations for the treatment of AS using a systematic literature search and categorizing the evidence.
    • Zochling J, van der Heijde D, Burgos-Vargas R, et al.: ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2006, 65:442-452. The authors present 10 key evidence-based recommendations for the treatment of AS using a systematic literature search and categorizing the evidence.
  • 10
    • 13444253765 scopus 로고    scopus 로고
    • van der Heijde D, Dijkmans B, Geusens P, et al.: Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT). Arthritis Rheum 2005, 52:582-591. The phase 3 ASSERT trial confirmed the safety and efficacy of infliximab in treating AS.
    • van der Heijde D, Dijkmans B, Geusens P, et al.: Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT). Arthritis Rheum 2005, 52:582-591. The phase 3 ASSERT trial confirmed the safety and efficacy of infliximab in treating AS.
  • 11
    • 0037007683 scopus 로고    scopus 로고
    • Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha
    • Gorman JD, Sack KE, Davis JC Jr: Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. N Engl J Med 2002, 346:1349-1356.
    • (2002) N Engl J Med , vol.346 , pp. 1349-1356
    • Gorman, J.D.1    Sack, K.E.2    Davis Jr, J.C.3
  • 12
    • 33745894976 scopus 로고    scopus 로고
    • van der Heijde D, Kivitz A, Schiff M, et al.: Efficacy and safety of adalimumab in patients with ankylosing spondylitis. Arthritis Rheum 2006, 54:2136-2146. The phase 3 ATLAS trial is the largest trial to date showing the safety and efficacy of adalimumab in the treatment of AS. This is also the first trial showing benefit in patients with complete spinal ankylosis.
    • van der Heijde D, Kivitz A, Schiff M, et al.: Efficacy and safety of adalimumab in patients with ankylosing spondylitis. Arthritis Rheum 2006, 54:2136-2146. The phase 3 ATLAS trial is the largest trial to date showing the safety and efficacy of adalimumab in the treatment of AS. This is also the first trial showing benefit in patients with complete spinal ankylosis.
  • 13
    • 21844445087 scopus 로고    scopus 로고
    • Sulfasalazine for ankylosing spondylitis
    • CD004800
    • Chen J, Liu C: Sulfasalazine for ankylosing spondylitis. Cochrane Database Syst Rev 2005, (2):CD004800.
    • (2005) Cochrane Database Syst Rev , vol.2
    • Chen, J.1    Liu, C.2
  • 14
    • 0028958732 scopus 로고
    • Sulfasalazine in the treatment of spondylarthropathy: A randomized, multicenter, double-blind, placebo-controlled study
    • Dougados M, van der Linden SM, Leirisalo-Repo M, et al.: Sulfasalazine in the treatment of spondylarthropathy: a randomized, multicenter, double-blind, placebo-controlled study. Arthritis Rheum 1995, 38:618-627.
    • (1995) Arthritis Rheum , vol.38 , pp. 618-627
    • Dougados, M.1    van der Linden, S.M.2    Leirisalo-Repo, M.3
  • 15
    • 16544373476 scopus 로고    scopus 로고
    • Methotrexate for ankylosing spondylitis
    • CD004524
    • Chen J, Liu C: Methotrexate for ankylosing spondylitis. Cochrane Database Syst Rev 2004, (3):CD004524.
    • (2004) Cochrane Database Syst Rev , vol.3
    • Chen, J.1    Liu, C.2
  • 16
    • 23844527232 scopus 로고    scopus 로고
    • Double blind, randomised, placebo controlled study of leflunomide in the treatment of active ankylosing spondylitis
    • van Denderen JC, van der Paardt M, Nurmohamed MT, et al.: Double blind, randomised, placebo controlled study of leflunomide in the treatment of active ankylosing spondylitis. Ann Rheum Dis 2005, 64:1761-1764.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1761-1764
    • van Denderen, J.C.1    van der Paardt, M.2    Nurmohamed, M.T.3
  • 18
    • 20244372400 scopus 로고    scopus 로고
    • Evaluation of the efficacy of etoricoxib in ankylosing spondylitis
    • van der Heijde D, Baraf H, Ramos-Remus C, et al.: Evaluation of the efficacy of etoricoxib in ankylosing spondylitis. Arthritis Rheum 2005, 52:1205-1215.
    • (2005) Arthritis Rheum , vol.52 , pp. 1205-1215
    • van der Heijde, D.1    Baraf, H.2    Ramos-Remus, C.3
  • 19
    • 0033028778 scopus 로고    scopus 로고
    • Periarticular corticosteroid treatment of the sacroiliac joint in patients with seronegative spondyloarthropathy
    • Luukkainen R, Nissila M, Asikainen E, et al.: Periarticular corticosteroid treatment of the sacroiliac joint in patients with seronegative spondyloarthropathy. Clin and Exp Rheumatol 1999, 17:88-90.
    • (1999) Clin and Exp Rheumatol , vol.17 , pp. 88-90
    • Luukkainen, R.1    Nissila, M.2    Asikainen, E.3
  • 20
    • 0036628581 scopus 로고    scopus 로고
    • Fluoroscopy-guided intraarticular corticosteroid injection into the sacroiliac joints in patients with ankylosing spondylitis
    • Karabacakoglu A, Karakose S, Ozerbil OM, Odev K: Fluoroscopy-guided intraarticular corticosteroid injection into the sacroiliac joints in patients with ankylosing spondylitis. Acta Radiol 2002, 43:425-427.
    • (2002) Acta Radiol , vol.43 , pp. 425-427
    • Karabacakoglu, A.1    Karakose, S.2    Ozerbil, O.M.3    Odev, K.4
  • 21
    • 0026509958 scopus 로고
    • Intravenous methylprednisolone pulse therapy in ankylosing spondylitis
    • Peters N, Ejstrup L: Intravenous methylprednisolone pulse therapy in ankylosing spondylitis. Scand J Rheumatol 1992, 21:134-138.
    • (1992) Scand J Rheumatol , vol.21 , pp. 134-138
    • Peters, N.1    Ejstrup, L.2
  • 22
    • 33747774889 scopus 로고    scopus 로고
    • Efficacy of sulfasalazine in patients with inflammatory back pain due to undifferentiated spondyloarthritis and early ankylosing spondylitis: A multicentre randomised controlled trial
    • Braun J, Zochling J, Baraliakos X, et al.: Efficacy of sulfasalazine in patients with inflammatory back pain due to undifferentiated spondyloarthritis and early ankylosing spondylitis: a multicentre randomised controlled trial. Ann Rheum Dis 2006, 65:1147-1153.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1147-1153
    • Braun, J.1    Zochling, J.2    Baraliakos, X.3
  • 23
    • 3442880132 scopus 로고    scopus 로고
    • Efficacy of methotrexate in ankylosing spondylitis: A randomized, double blind, placebo controlled trial
    • Gonzalez-Lopez L, Garcia-Gonzalez M, Vazque-Del-Mercado M, et al.: Efficacy of methotrexate in ankylosing spondylitis: a randomized, double blind, placebo controlled trial. J Rheumatol 2004, 31:1568-1574.
    • (2004) J Rheumatol , vol.31 , pp. 1568-1574
    • Gonzalez-Lopez, L.1    Garcia-Gonzalez, M.2    Vazque-Del-Mercado, M.3
  • 24
    • 22144494850 scopus 로고    scopus 로고
    • Infliximab in combination with methotrexate in active ankylosing spondylitis: A clinical and imaging study
    • Marzo-Ortega H, McGonagle D, Jarrett S, et al.: Infliximab in combination with methotrexate in active ankylosing spondylitis: a clinical and imaging study. Ann Rheum Dis 2005, 64:1568-1575.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1568-1575
    • Marzo-Ortega, H.1    McGonagle, D.2    Jarrett, S.3
  • 25
    • 34248232034 scopus 로고    scopus 로고
    • Increased efficacy of infliximab associated with methotrexate in ankylosing spondylitis
    • Perez-Guijo V, Cravo A, Castro Mdel C, et al.: Increased efficacy of infliximab associated with methotrexate in ankylosing spondylitis. Joint Bone Spine 2007, 74:254-258.
    • (2007) Joint Bone Spine , vol.74 , pp. 254-258
    • Perez-Guijo, V.1    Cravo, A.2    Castro Mdel, C.3
  • 26
    • 0036188770 scopus 로고    scopus 로고
    • A six-month randomized, controlled, double-blind, dose-response comparison of intravenous Pamidronate (60mg versus 10mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis
    • Maksymowych W, Jhangri GS, Fitzgerald A, et al.: A six-month randomized, controlled, double-blind, dose-response comparison of intravenous Pamidronate (60mg versus 10mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis. Arthritis Rheum 2002, 46:766-773.
    • (2002) Arthritis Rheum , vol.46 , pp. 766-773
    • Maksymowych, W.1    Jhangri, G.S.2    Fitzgerald, A.3
  • 27
    • 0035171329 scopus 로고    scopus 로고
    • Clinical and radiological amelioration of refractory peripheral spondyloarthritis by pulse intravenous Pamidronate therapy
    • Maksymowych W, Lambert RG, Jhangri GS, et al.: Clinical and radiological amelioration of refractory peripheral spondyloarthritis by pulse intravenous Pamidronate therapy. J Rheumatol 2001, 28:144-155.
    • (2001) J Rheumatol , vol.28 , pp. 144-155
    • Maksymowych, W.1    Lambert, R.G.2    Jhangri, G.S.3
  • 28
    • 35348979874 scopus 로고    scopus 로고
    • Toussirot E, Lohse A, Le Huede G, et al.: Treatment of refractory and active spondylarthropathies with Pamidronate: an open study [abstract #SAT0026]. Presented at the European League Against Rheumatism. Berlin; June 19-24, 2004.
    • Toussirot E, Lohse A, Le Huede G, et al.: Treatment of refractory and active spondylarthropathies with Pamidronate: an open study [abstract #SAT0026]. Presented at the European League Against Rheumatism. Berlin; June 19-24, 2004.
  • 29
    • 0348109367 scopus 로고    scopus 로고
    • Thalidomide for severe refractory ankylosing spondylitis: A 6-month open-label trial
    • Wei JC, Chan TW, Lin HS, et al.: Thalidomide for severe refractory ankylosing spondylitis: a 6-month open-label trial. J Rheumatol 2003, 30:2627-2631.
    • (2003) J Rheumatol , vol.30 , pp. 2627-2631
    • Wei, J.C.1    Chan, T.W.2    Lin, H.S.3
  • 30
    • 0037097746 scopus 로고    scopus 로고
    • One-year open-label trial of thalidomide in ankylosing spondylitis
    • Huang F, Gu J, Zhao W, et al.: One-year open-label trial of thalidomide in ankylosing spondylitis. Arthritis Rheum 2002, 47:249-254.
    • (2002) Arthritis Rheum , vol.47 , pp. 249-254
    • Huang, F.1    Gu, J.2    Zhao, W.3
  • 31
    • 13244279795 scopus 로고    scopus 로고
    • Open label trial of anakinra in active ankylosing spondylitis over 24 weeks
    • Haibel H, Rudwaleit M, Listing J, Sieper J: Open label trial of anakinra in active ankylosing spondylitis over 24 weeks. Ann Rheum Dis 2005, 64:296-298.
    • (2005) Ann Rheum Dis , vol.64 , pp. 296-298
    • Haibel, H.1    Rudwaleit, M.2    Listing, J.3    Sieper, J.4
  • 32
    • 0037029430 scopus 로고    scopus 로고
    • Treatment of active ankylosing spondylitis with infliximab: A randomised controlled multicentre trial
    • Braun J, Brandt J, Listing J, et al.: Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial. Lancet 2002, 359:1187-1193.
    • (2002) Lancet , vol.359 , pp. 1187-1193
    • Braun, J.1    Brandt, J.2    Listing, J.3
  • 33
    • 21244449214 scopus 로고    scopus 로고
    • Persistent clinical response to the anti-TNF-alpha antibody infliximab in patients with ankylosing spondylitis over 3 years
    • Braun J, Baraliakos X, Brandt J, et al.: Persistent clinical response to the anti-TNF-alpha antibody infliximab in patients with ankylosing spondylitis over 3 years. Rheumatology (Oxford) 2005, 44:670-676.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 670-676
    • Braun, J.1    Baraliakos, X.2    Brandt, J.3
  • 34
    • 35348934542 scopus 로고    scopus 로고
    • Visvanathan S, Deodhar A, Braun J, et al.: Modulation of biomarkers of inflammation and bone turnover and associations with bone mineral density in ankylosing spondylitis patients treated with infliximab [abstract #Sat0317]. Presented at the European League Against Rheumatism. Amsterdam; June 21-24, 2006.
    • Visvanathan S, Deodhar A, Braun J, et al.: Modulation of biomarkers of inflammation and bone turnover and associations with bone mineral density in ankylosing spondylitis patients treated with infliximab [abstract #Sat0317]. Presented at the European League Against Rheumatism. Amsterdam; June 21-24, 2006.
  • 35
    • 0242411795 scopus 로고    scopus 로고
    • Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis
    • Davis JC Jr, van der Heijde D, Braun J, et al.: Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis. Arthritis Rheum 2003, 48:3230-3236.
    • (2003) Arthritis Rheum , vol.48 , pp. 3230-3236
    • Davis Jr, J.C.1    van der Heijde, D.2    Braun, J.3
  • 36
    • 23644459274 scopus 로고    scopus 로고
    • Sustained durability and tolerability of etanercept in ankylosing spondylitis for 96 weeks
    • Davis JC Jr, van der Heijde D, Braun J, et al.: Sustained durability and tolerability of etanercept in ankylosing spondylitis for 96 weeks. Ann Rheum Dis 2005, 64:1557-1562.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1557-1562
    • Davis Jr, J.C.1    van der Heijde, D.2    Braun, J.3
  • 37
    • 84868343671 scopus 로고    scopus 로고
    • Spondyloarthritis Research and Treatment Network:, Available at, Accessed July 23, 2007
    • Spondyloarthritis Research and Treatment Network: SPARTAN Educational Slide Set. Available at http://www.spartangroup.org/. Accessed July 23, 2007.
    • SPARTAN Educational Slide Set
  • 38
    • 20744445686 scopus 로고    scopus 로고
    • Wanders A, van der Heijde D, Landewe, et al.: Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis. Arthritis Rheum 2005, 52:1756-1765. This is the only trial to date that shows a reduction in radiographic progression with an AS treatment.
    • Wanders A, van der Heijde D, Landewe, et al.: Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis. Arthritis Rheum 2005, 52:1756-1765. This is the only trial to date that shows a reduction in radiographic progression with an AS treatment.
  • 39
    • 33646483500 scopus 로고    scopus 로고
    • Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab
    • Braun J, Landewe R, Hermann KG, et al.: Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab. Arthritis Rheum 2006, 54:1646-1652.
    • (2006) Arthritis Rheum , vol.54 , pp. 1646-1652
    • Braun, J.1    Landewe, R.2    Hermann, K.G.3
  • 40
    • 0037388280 scopus 로고    scopus 로고
    • Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with infliximab
    • Braun J, Baraliakos X, Golder W, et al.: Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with infliximab. Arthritis Rheum 2003, 48:1126-1136.
    • (2003) Arthritis Rheum , vol.48 , pp. 1126-1136
    • Braun, J.1    Baraliakos, X.2    Golder, W.3
  • 41
    • 35348951748 scopus 로고    scopus 로고
    • van der Heijde D: Two-year etanercept therapy does not inhibit radiographic progression in patients with AS [abstract #OP0090]. Presented at the European League Against Rheumatism. Amsterdam; June 21-24, 2006. The author reports that etanercept does not inhibit radiographic progression in AS as compared to a historic cohort.
    • van der Heijde D: Two-year etanercept therapy does not inhibit radiographic progression in patients with AS [abstract #OP0090]. Presented at the European League Against Rheumatism. Amsterdam; June 21-24, 2006. The author reports that etanercept does not inhibit radiographic progression in AS as compared to a historic cohort.
  • 42
    • 35348964312 scopus 로고    scopus 로고
    • van der Heijde D, Landewe R, Deodhar A, et al.: Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment not inhibited with infliximab [abstract #OPO111]. Presented at the European League Against Rheumatism. Barcelona; June 13-16, 2007.
    • van der Heijde D, Landewe R, Deodhar A, et al.: Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment not inhibited with infliximab [abstract #OPO111]. Presented at the European League Against Rheumatism. Barcelona; June 13-16, 2007.
  • 43
    • 35348967558 scopus 로고    scopus 로고
    • Brandt J, Listing J, Krause A, et al.: Socioeconomic consequences for patients with active ankylosing spondylitis treated for two years with infliximab in a clinical trial [abstract #FRI0201]. Presented at the European League Against Rheumatism. Lisbon; June 18-21, 2003.
    • Brandt J, Listing J, Krause A, et al.: Socioeconomic consequences for patients with active ankylosing spondylitis treated for two years with infliximab in a clinical trial [abstract #FRI0201]. Presented at the European League Against Rheumatism. Lisbon; June 18-21, 2003.
  • 44
    • 35348976848 scopus 로고    scopus 로고
    • van der Heijde D, DeVlam K, Burmester G, et al.: Infliximab improves productivity in employed patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT) [abstract #SAT0044]. Presented at the European League Against Rheumatism. Berlin; June 9-12, 2004.
    • van der Heijde D, DeVlam K, Burmester G, et al.: Infliximab improves productivity in employed patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT) [abstract #SAT0044]. Presented at the European League Against Rheumatism. Berlin; June 9-12, 2004.
  • 45
    • 33645829608 scopus 로고    scopus 로고
    • The cost-effectiveness of infliximab (Remicade) in the treatment of ankylosing spondylitis in Canada
    • Using a disease model adapted to the Canadian setting, the authors show that infliximab is cost-effective in their system
    • Kobelt G, Andlin-Sobocki P, Maksymowych W: The cost-effectiveness of infliximab (Remicade) in the treatment of ankylosing spondylitis in Canada. J Rheumatol 2006, 33:732-740. Using a disease model adapted to the Canadian setting, the authors show that infliximab is cost-effective in their system.
    • (2006) J Rheumatol , vol.33 , pp. 732-740
    • Kobelt, G.1    Andlin-Sobocki, P.2    Maksymowych, W.3
  • 46
    • 0034901476 scopus 로고    scopus 로고
    • Total hip arthroplasty in ankylosing spondylitis: Outcome in 340 patients
    • Sweeney S, Gupta R, Taylor G, Calin A: Total hip arthroplasty in ankylosing spondylitis: outcome in 340 patients. J Rheumatol 2001, 28:1862-1868.
    • (2001) J Rheumatol , vol.28 , pp. 1862-1868
    • Sweeney, S.1    Gupta, R.2    Taylor, G.3    Calin, A.4
  • 47
    • 0033021221 scopus 로고    scopus 로고
    • Lumbar osteotomy for correction of thoracolumbar kyphotic deformity in ankylosing spondylitis. A structured review of three methods of treatment
    • van Royen BJ, De Gast A: Lumbar osteotomy for correction of thoracolumbar kyphotic deformity in ankylosing spondylitis. A structured review of three methods of treatment. Ann Rheum Dis 1999, 58:399-406.
    • (1999) Ann Rheum Dis , vol.58 , pp. 399-406
    • van Royen, B.J.1    De Gast, A.2
  • 48
    • 35349026156 scopus 로고    scopus 로고
    • Increased levels of soluble Ctla-4 molecule in serum of patients with spondyloarthropathies
    • abstract #1103-362, Presented at the, serum of patients with SpA suggests that there might be a role for abatacept therapy in SpA
    • Toussirot E, Saas P, Pouthier F, et al.: Increased levels of soluble Ctla-4 molecule in serum of patients with spondyloarthropathies [abstract #1103-362]. Presented at the American College of Rheumatology Annual Meeting. Washington, DC; November 10-15, 2006. The increased levels of CTLA-4 in the serum of patients with SpA suggests that there might be a role for abatacept therapy in SpA.
    • American College of Rheumatology Annual Meeting. Washington, DC; November 10-15, 2006. The increased levels of CTLA-4
    • Toussirot, E.1    Saas, P.2    Pouthier, F.3
  • 49
    • 33846949349 scopus 로고    scopus 로고
    • Diarra D, Stolina M, Polzer K, et al.: Dickkopf-1 is a master regulator of joint remodeling. Nature Med 2007, 13:156-163. New data on DKK-1 as a regulator of the Wnt pathway, known to be important in osteoblastic bone formation, may play a role in understanding the current disconnect between improvement in disease activity achieved by TNF inhibitors and their inability to prevent radiographic progression.
    • Diarra D, Stolina M, Polzer K, et al.: Dickkopf-1 is a master regulator of joint remodeling. Nature Med 2007, 13:156-163. New data on DKK-1 as a regulator of the Wnt pathway, known to be important in osteoblastic bone formation, may play a role in understanding the current disconnect between improvement in disease activity achieved by TNF inhibitors and their inability to prevent radiographic progression.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.