Synthesis and in vitro biochemical evaluation of a series of cycloalkyl esters of 4-sulfamoylated benzoic acid as inhibitors of estrone sulfatase (ES)

Letters in Drug Design and Discovery

Volumn 4, Issue 6, 2007, Pages 399-403

  Owen, Caroline P ^a   Patel, Chirag K ^a   Cartledge, Tim ^a   Ahmed, Sabbir ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

Breast cancer; Cycloalkyl esters; Estrone sulfatase; Evaluation; Inhibition; Synthesis

Indexed keywords

4 [(AMINOSULFONYL)OXY]BENZOATE; 4 SULFAMOYLATED BENZOIC ACID; BENZOIC ACID DERIVATIVE; CYCLOBUTYLMETHYL 4 AMINOSULFONYLBENZOATE; CYCLOBUTYLMETHYL 4 HYDROXYBENZOATE; ESTRONE SULFATASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL;

EID: 35348975020     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018007781387845     Document Type: Article

References (9)

1. Feutrie, M. L.; Bonneterre, J. Bulletin Cancer, 1999, 86, 821.
2. Selcer, K. W.; Kabler, H.; Sarap, J.; Xiao, Z.; Li, P-K. Steroids, 2002, 67, 821.
3. Ahmed, S.; Owen, C. P.; James, K.; Sampson, L.; and Patel, C. K. Curr. Med. Chem., 2002, 9, 263.
4. Ahmed, S.; Owen, C.; James, K.; Patel, C. K.; Patel, M. Bioorg. Med. Chem. Lett., 2001, 11, 2525.
5. Ahmed, S.; James, K.; Owen, C. P.; Patel, C. K.; Patel, M. Bioorg. Med. Chem. Lett., 2001, 11, 841.
6. Ahmed, S.; James, K.; Owen, C. P. Bioorg. Med. Chem. Lett., 2002, 12, 2391.
7. Owen, C.; James, K.; Sampson, L.; Ahmed, S. J. Pharmacy Pharmacol., 2003, 1, 85.
8. Patel, C. K.; Owen, C. P.; Ahmed, S. Bioorg. Med. Chem. Lett., 2004, 14, 605.
9. Ahmed, S.; Owen, C.; James, K.; Patel, C. K.; Patel, M. Bioorg. Med. Chem. Lett., 2001, 11, 3001.