Implications of Tropomyosin-related kinase B (TrkB) in head and neck cancer

Anticancer Research

Volumn 27, Issue 5 A, 2007, Pages 3121-3126

  Zhu, Li ^a   Werner, Jochen A ^a   Mandic, Robert ^a  

^a UNIVERSITY HOSPITAL MARBURG   (Germany)

Author keywords

Brain derived neurotrophic factor; Head and neck squamous cell carcinoma; Invasiveness; Tropomyosin related kinase B

Indexed keywords

AVIDIN; BRAIN DERIVED NEUROTROPHIC FACTOR; PROTEIN KINASE B; TROPOMYOSIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER INVASION; CONTROLLED STUDY; FEMALE; FLUORESCENCE; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DOGS; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; RECEPTOR, TRKB;

EID: 35348966314     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Werner JA, Rathcke IO and Mandic R: The role of matrix metalloproteinases in squamous cell carcinomas of the head and neck. Clin Exp Metastasis 19: 275-282, 2002.
2. Liotta LA and Kohn E: Anoikis: cancer and the homeless cell. Nature 430: 973-974, 2004.
3. Douma S, Van LT, Zevenhoven J, Meuwissen R, Van GE and Peeper DS: Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 430: 1034-1039, 2004.
4. Klein R, Parada LF, Coulier F and Barbacid M: TrkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. EMBO J 8: 3701-3709, 1989.
5. Huang EJ and Reichardt LF: Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72: 609-642, 2003.
6. Shelton DL, Sutherland J, Gripp J, Camerato T, Armanini MP, Phillips HS, Carroll K, Spencer SD and Levinson AD: Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins. J Neurosci 15: 477-491, 1995.
7. Chen-Tsai CP, Colome-Grimmer M and Wagner RF Jr: Correlations among neural cell adhesion molecule, nerve growth factor, and its receptors, TrkA, TrkB, TrkC, and p75, in perineural invasion by basal cell and cutaneous squamous cell carcinomas. Dermatol Surg 30: 1009-1016, 2004.
8. Geiger TR and Peeper DS: The neurotrophic receptor TrkB in anoikis resistance and metastasis: a perspective. Cancer Res 65: 7033-7036, 2005.
9. Pearse RN, Swendeman SL, Li Y, Rafii D and Hempstead BL: A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival. Blood 105: 4429-4436, 2005.
10. Lansford C, Grenman R, Bier H, Somers KD, Kim S-Y, Whiteside TL, Clayman G and Carey TE: Head and Neck Cancers. In: Human Cell Culture Vol 2, Cancer Cell Lines Part 2. Masters J (ed.). Dordrecht (Holland), Kluwer Academic Press, pp. 185-255, 1999.
11. Mandic R, Schamberger CJ, Muller JF, Geyer M, Zhu L, Carey TE, Grenman R, Dunne AA and Werner JA: Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53. Clin Cancer Res 11: 6845-6852, 2005.
12. Zak J, Schneider SW, Eue I, Ludwig T and Oberleithner H: High-resistance MDCK-C7 monolayers used for measuring invasive potency of tumour cells. Pflugers Arch 440: 179-183, 2000.
13. Mandic R, Ludwig T, Oberleithner H and Werner JA: Evaluation of head and neck squamous cell carcinoma invasiveness by the electrical resistance breakdown assay. Clin Exp Metastasis 21: 699-704, 2004.
14. Ho R, Eggert A, Hishiki T, Minturn JE, Ikegaki N, Foster P, Camoratto AM, Evans AE and Brodeur GM: Resistance to chemotherapy mediated by TrkB in neuroblastomas. Cancer Res 62: 6462-6466, 2002.
15. Undevia SD, Vogelzang NJ, Mauer AM, Janisch L, Mani S and Ratain MJ: Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors. Invest New Drugs 22: 449-458, 2004.