A fast CE method for the achiral separation of methadone and its major metabolites, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline

Electrophoresis

Volumn 28, Issue 19, 2007, Pages 3566-3569

  Kelly, Tamsin ^a,b   Doble, Philip ^a   Dawson, Michael ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b CURTIN UNIVERSITY   (Australia)

Author keywords

2 ethyl 5 methyl 3,3 diphenyl 1 pyrroline; 2 ethylidene 1,5 dimethyl 3, 3 diphenylpyrrolidine; Dynamic doubly coated capillaries; Methadone; Poly(diallyl dimethylammonium chloride

Indexed keywords

BIOMOLECULES; CAPILLARITY; CHLORINE COMPOUNDS; SULFUR COMPOUNDS;

2-ETHYL-5-METHYL-3,3-DIPHENYL-1-PYRROLINE; 2-ETHYLIDENE-1,5-DIMETHYL-3, 3-DIPHENYLPYRROLIDINE; COATED CAPILLARIES; DYNAMIC DOUBLY COATED CAPILLARY; FAST SEPARATION; METHADONE; POLY (DIALLYLDIMETHYLAMMONIUM CHLORIDE); POLYCATIONS; POLYDIALLYLDIMETHYL AMMONIUM CHLORIDE; PYRROLINES;

METABOLITES;

2 ETHYL 5 METHYL 3,3 DIPHENYL 1 PYRROLINE; 2 ETHYLIDENE 1,5 DIMETHYL 3,3 DIPHENYLPYRROLIDINE; DEXTRAN SULFATE; METHADONE; OPIATE; PHOSPHATE; POLY(DIALLYLDIMETHYLAMMONIUM CHLORIDE); UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; DRUG DETERMINATION; DRUG ISOLATION; MATERIAL COATING; PH;

EID: 35348942357     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200700090     Document Type: Article

References (18)

1. Frazier, R. A., Ames, J. M., Nursten, H. E., Capillary Electrophoresis for Food Analysis: Method Development, Royal Society of Chemistry, London 2000.
2. Altria, K. D., J. Pharm. Biomed. Anal. 2003, 31, 447-453.
3. Lurie, I. S., Bethea, J., McKibben, T. D., Hays, P. A. et al., J. Forensic Sci. 2001, 46, 1025-1032.
4. Zakaria, P., Macka, M., Haddad, P. R., Electrophoresis 2002, 23, 1844-1852.
5. Zakaria, P., Macka, M., Haddad, P. R., J. Chromatogr. A 2003, 985, 493-501.
6. Lurie, I. S., Panicker, S., Hays, P. A., Garcia, A. D. et al., J. Chromatogr. A 2003, 984, 109-120.
7. Boone, C. M., Jonkers, E. Z., Franke, J. P., de Zeeuw, R. A. et al., J. Chromatogr. A 2001, 927, 203-210.
8. Trkulja, S., Kovar, K. A., J. Sep. Sci. 2004, 27, 557-559.
9. Esteban, J., Pellin, M. d. I. C., Gimeno, C., Barril, J. et al., Toxicol. Lett. 2004, 151, 243-249.
10. Lanz, M., Thormann, W., Electrophoresis 1996, 17, 1945-1949.
11. Frost, M., Köhler, H., Blaschke, G., Electrophoresis 1997, 18, 1026-1034.
12. Ramseier, A., Caslavska, J., Thormann, W., Electrophoresis 1999, 20, 2726-2738.
13. Cherkaoui, S., Rudaz, S., Varesio, E., Veuthey, J.-L., Electrophoresis 2001, 22, 3308-3315.
14. Rudaz, S., Cherkaoui, S., Gauvrit, J.-Y., Lantéri, P. et al., Electrophoresis 2001, 22, 3316-3326.
15. Thormann, W., Caslavska, J., Ramseier, A., Siethoff, C., J. Microcol. Sep. 2000, 12, 13-24.
16. Kelly, T., Doble, P., Dawson, M., Electrophoresis 2003, 24, 2106-2110.
17. Thormann, W., Lanz. M., Caslavska, J., Siegenthaler, P. et al., Electrophoresis 1998, 19, 57-65.
18. Molteni, S., Caslavska, J., Alleman, D., Thormann, W., J. Chromatogr. B 1994, 658, 355-367.