Characterization of the stereoselective metabolism of methadone and its primary metabolite via cyclodextrin capillary electrophoretic determination of their urinary enantiomers

Electrophoresis

Volumn 17, Issue 12, 1996, Pages 1945-1949

  Lanz, Matthias ^a   Thormann, Wolfgang ^a,b  

^a UNIVERSITY OF BERN   (Switzerland)

^b Department of Clinical Pharmacology ^*  (Switzerland)

Author keywords

Capillary electrophoresis; Cyclodextrin; Methadone; Stereoselective metabolism

Indexed keywords

BIOMOLECULES; CYCLODEXTRINS; ENANTIOMERS; FUSED SILICA; METABOLISM; METABOLITES; PATIENT TREATMENT; PHASE SEPARATION; PHYSIOLOGY; STEREOSELECTIVITY;

CAPILLARY-ZONE ELECTROPHORESIS; CHIRAL SELECTOR; ENANTIOMERIC RATIO; METHADONE; PHOSPHATE BUFFERS; PRIMARY METABOLITE; SIMULTANEOUS SEPARATION; SOLID-PHASE EXTRACTION; STEREO-SELECTIVE; STEREOSELECTIVE METABOLISM;

CAPILLARY ELECTROPHORESIS;

DRUG METABOLITE; METHADONE;

CAPILLARY ZONE ELECTROPHORESIS; CONFERENCE PAPER; CONTROLLED STUDY; DERIVATIZATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG URINE LEVEL; HUMAN; HUMAN TISSUE; ORAL DRUG ADMINISTRATION; STEREOCHEMISTRY;

EID: 0030465664     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.1150171223     Document Type: Conference Paper

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