Ricinus communis contains an acyl-CoA synthetase that preferentially activates ricinoleate to its CoA thioester

Lipids

Volumn 42, Issue 10, 2007, Pages 931-938

  He, Xiaohua ^a   Chen, Grace Q ^a   Kang, Sung T ^b   McKeon, Thomas A ^a  

^a WESTERN REGIONAL RESEARCH CENTER   (United States)

^b Seoul National University of Science and Technology   (South Korea)

Author keywords

Acyl CoA synthetase; Complementation test; Real time PCR; Ricinus communis; Saccharomyces cerevisiae; Substrate specificity

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; DNA; OILS AND FATS; YEAST;

ACYL-COA SYNTHETASE; COMPLEMENTATION TEST; REAL-TIME PCR; RICINUS COMMUNIS; SUBSTRATE SPECIFICITY;

ENZYMES;

CARBON 14; COMPLEMENTARY DNA; HYDROXY FATTY ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; OLEIC ACID; RICINOLEIC ACID; THIOESTER;

AMINO ACID SEQUENCE; ARTICLE; CELL LYSATE; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME SPECIFICITY; GENETIC CODE; GENETIC COMPLEMENTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RICINUS COMMUNIS; SACCHAROMYCES CEREVISIAE; YEAST;

AMINO ACID SEQUENCE; CASTOR BEAN; CLONING, MOLECULAR; COENZYME A LIGASES; DNA, COMPLEMENTARY; GENETIC COMPLEMENTATION TEST; MOLECULAR SEQUENCE DATA; PLANT PROTEINS; RICINOLEIC ACIDS; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

RICINUS COMMUNIS; SACCHAROMYCES CEREVISIAE;

EID: 35348902622     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-007-3090-0     Document Type: Article

References (28)

1. Caupin HJ (1997) Products from castor oil: past, present, and future, in lipid technologies and applications. Gunstone FD, Padley FB (eds) Marcel Dekker, New York, pp 787-795
2. Voelker TA, Hayes TR, Cranmer AM, Turner JC, Davies HM (1996) Genetic engineering of a quantitative trait: metabolic and genetic parameters influencing the accumulation of laurate in rapeseed. Plant J 9:229-241
3. Eccleston VS, Ohlrogge JB (1998) Expression of lauroyl-acyl carrier protein thioesterase in Brassica napus seeds induces pathways for both fatty acid oxidation and biosynthesis and implies a set point for triacylglycerol accumulation. Plant Cell 10:613-622
4. Knutzon DS, Hayes TR, Wyrick A, Xiong H, Davies HM, Voelker TA (1999) Lysophosphatidic acid acyltransferase from coconut endosperm mediates the insertion of laurate at the sn-2 position of triacylglycerols in lauric rapeseed oil and can increase total laurate levels. Plant Physiol 120:739-746
5. Van de Loo FJ, Broun P, Turner S, Somerville C (1995) An oleate 12-hydroxylase from Ricinus communis L. Is a fatty acyl desaturase homolog. Proc Natl Acad Sci USA 92:6743-6747
6. Broun P, Somerville C (1997) Accumulation of ricinoleic, lesquerolic, and densipolic acids in seeds of transgenic Arabidopsis plants that express a fatty acyl hydroxylase cDNA from castor bean. Plant Physiol 113:933-942
7. Millar AA, Smith MA, Kunst L (2000) All fatty acids are not equal: discrimination in plant membrane lipids. Trends Plant Sci 5:95-101
8. Bafor M, Smith MA, Jonsson L, Stobart K, Stymne S (1991) Ricinoleic acid biosynthesis and triacylglycerol assembly in microsomal preparations from developing castor bean (Ricinus communis) endosperm. Biochem J 280:507-514
9. Lin JT, Woodruff CL, Lagouche OJ, McKeon TA, Stafford AE, Goodrich-Tanrikulu M, Singleton JA, Haney CA (1998) Biosynthesis of triacylglycerols containing ricinoleate in castor microsomes using 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine as the substrate of oleoyl-12-hydroxylase. Lipids 33:59-69
10. He H, Turner C, Chen GQ, Lin JT, McKeon TA (2004) Cloning and characterization of a cDNA encoding diacylglycerol acyltransferase from castor bean. Lipids 39:311-318
11. Fulda M, Heinz E, Wolter FP (1997) Brassica napus cDNA encoding fatty acyl-CoA synthetase. Plant Mol Biol 33:911-922
12. Schnurr JA, Shockey JM, de Boer GJ, Browse JA (2002) Fatty acid export from the chloroplast. Molecular characterization of a major plastidial acyl-coenzyme A synthetase from Arabidopsis. Plant Physiol 129:1700-1709
13. Van Horn CG, Cavigilia JM, Li LO, Wang SL, Granger DA, Coleman RA (2005) Characterization of recombinant long-chain acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6. Biochemistry 44:1635-1642
14. Gu YQ, Yang C, Thara VK, Zhou J, Martin GB (2000) Pti4 is induced by ethylene and salicylic acid, and its product is phosphorylated by the pto kinase. Plant Cell 12:771-785
15. Schaefer BC (1995) Revolutions in rapid amplification of cDNA ends: new strategies for polymerase chain reaction cloning of full-length cDNA ends. Anal Biochem 227:255-273
16. Knoll LJ, Johnson DR, Gordon JI (1995) Complementation of Saccharomyces cerevisiae strains containing fatty acid activation gene (FAA) deletions with a mammalian acyl-CoA synthetase. J Biol Chem 270:10861-10867
17. Urban P, Werck-Reichhart D, Teutsch HG, Durst F, Regnier S, Kazmaier M, Pompon D (1994) Characterization of recombinant plant cinnamate 4-hydroxylase produced in yeast. Kinetic and spectral properties of the major plant P450 of the phenylpropanoid pathway. Eur J Biochem 222:843-850
18. Shockey JM, Fulda MS, Browse JA (2002) Arabidopsis contains nine long-chain acyl-coenzyme A synthetase genes that participate in fatty acid and glycerolipid metabolism. Plant Physiol 129:1710-1722
19. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:2002-2007
20. Black PN, DiRusso CC, Metzger AK, Heimert TL (1992) Cloning, sequencing, and expression of the fadD gene of Escherichia coli encoding acyl coenzyme A synthetase. J Biol Chem 267:25513-25520
21. Fargeman NJ, Black PN, Zhao XD, Knudsen J, DiRusso CC (2001) The acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular utilization. J Biol Chem 276:37051-37059
22. Schmelter T, Trigatti BL, Gerber GE, Mangroo D (2004) Biochemical demonstration of the involvement of fatty acyl-CoA synthetase in fatty acid translocation across the plasma membrane. J Biol Chem 279:24163-24170
23. Hayashi H, Bellis LD, Hayashi Y, Nito K, Lato A, Hayashi M, Hara-Nishimura I, Nishimura M (2002) Molecular characterization of an Arabidopsis acyl-coenzyme A synthetase localized on glyoxysomal membranes. Plant Physiol 130:2019-2026
24. Jiang DW, Englund PT (2001) Four Trypanosomia brucei fatty acyl-coa synthetases: fatty acid specificity of the recombinant proteins. Biochem J 358:757-761
25. Reumann S, Ma C, Lemke S, Babujee L (2004) Araperox. a database of putative arabidopsis proteins from plant peroxisomes. Plant Physiol 136:2587-2608
26. Lu CF, Fulda M, Wallis JG, Browse J (2006) A high-throughput screen for genes from castor that boost hydroxy fatty acid accumulation in seed oils of transgenic Arabidopsis. Plant J 45:847-856
27. McKeon TA, Lin JT (2002) Biosynthesis of ricinoleic acid for castor oil production, in lipid biotechnology. Kuo TM, Gardner HW (eds) Marcel Dekker, New York, pp 129-139
28. Ichihara K, Yamane K, Hirano E (1997) Acyl-CoA synthetase in oilseeds: fatty acid structural requirements for activity and selectivity. Plant Cell Physiol 38(6):717-724