Elevated soluble receptor activator of nuclear factor-κB ligand and reduced bone mineral density in patients with adolescent idiopathic scoliosis

European Spine Journal

Volumn 16, Issue 10, 2007, Pages 1563-1569

  Suh, Kuen Tak ^a   Lee, Sang Sup ^b   Hwang, Sang Hyun ^a   Kim, Seong Jang ^a   Lee, Jung Sub ^a  

^a Pusan National University School of Medicine   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

Adolescent idiopathic scoliosis; Bone mineral density; OPG; RANKL

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN;

ADOLESCENT; ADOLESCENT DISEASE; ARTICLE; BONE DENSITY; BONE MASS; CLINICAL ARTICLE; FEMALE; FEMUR NECK; HUMAN; IDIOPATHIC SCOLIOSIS; LUMBAR SPINE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCHOOL CHILD;

ADOLESCENT; BONE DENSITY; CASE-CONTROL STUDIES; FEMALE; HUMANS; RANK LIGAND; SCOLIOSIS; SOLUBILITY;

EID: 35348829809     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-007-0390-2     Document Type: Article

References (31)

1. Ahn UM, Ahn NU, Nallamshetty L, Buchowski JM, Rose PS, Miller NH, Kostuik JP, Sponseller PD (2002) The etiology of adolescent idiopathic scoliosis. Am J Orthop 31:387-395
2. Baek KH, Oh KW, Lee WY, Tae HJ, Rhee EJ, Han JH, Cha BY, Kim YJ, Lee KW, Son HY, Kang SK, Kim CC, Kang MI (2006) Changes in the serum sex steroids, IL-7 and RANKL-OPG system after bone marrow transplantation: influences on bone and mineral metabolism. Bone 39:1352-1360
3. Burner WL, Badger VM, Sherman FC (1982) Osteoporosis and acquired back deformities. J Pediatr Orthop 2:383-385
4. Capparelli C, Morony S, Warmington K, Adamu S, Lacey D, Dunstan CR, Stouch B, Martin S, Kostenuik PJ (2003) Sustained antiresorptive effects after a single treatment with human recombinant osteoprotegerin (OPG): a pharmacodynamic and pharmacokinetic analysis in rats. J Bone Miner Res 18:852-858
5. Cheng JC, Guo X (1997) Osteopenia in adolescent idiopathic scoliosis. A primary problem or secondary to the spinal deformity? Spine 22:1716-1721
6. Cheng JC, Guo X, Sher AH (1999) Persistent osteopenia in adolescent idiopathic scoliosis. A longitudinal follow up study. Spine 24:1218-1222
7. Cheng JC, Leung SS, Lee WT, Lau JT, Maffulli N, Cheung AY, Chan KM (1998) Determinants of axial and peripheral bone mass in Chinese adolescents. Arch Dis Child 78:524-530
8. Cheng JC, Qin L, Cheung CS, Sher AH, Lee KM, Ng SW, Guo X (2000) Generalized low areal and volumetric bone mineral density in adolescent idiopathic scoliosis. J Bone Miner Res 15:1587-1595
9. Cheng JC, Tang SP, Guo X, Chan CW, Qin L (2001) Osteopenia in adolescent idiopathic scoliosis: a histomorphometric study. Spine 26:E19-E23
10. Cook SD, Harding AF, Morgan EL, Nicholson RJ, Thomas KA, Whitecloud TS, Ratner ES (1987) Trabecular bone mineral density in idiopathic scoliosis. J Pediatr Orthop 7:168-174
11. Crotti TN, Smith MD, Weedon H, Ahern MJ, Findlay DM, Kraan M, Tak PP, Haynes DR (2002) Receptor activator NF-kappaB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semiquantitative and quantitative analysis. Ann Rheum Dis 61:1047-1054
12. Ford DM, Bagnall KM, Clements CA, McFadden KD (1988) Muscle spindles in the paraspinal musculature of patients with adolescent idiopathic scoliosis. Spine 13:461-465
13. Ford DM, Bagnall KM, McFadden KD, Greenhill BJ, Raso VJ (1984) Paraspinal muscle imbalance in adolescent idiopathic scoliosis. Spine 9:373-376
14. Garcia Palacios V, Robinson LJ, Borysenko CW, Lehmann T, Kalla SE, Blair HC (2005) Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 Cells by estrogen and phytoestrogens. J Biol Chem 280:13720-13727
15. Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, Zannetino A, Ahern MJ, Coleman M, Roberts-Thomson PJ, Kraan M, Tak PP, Smith MD (2003) Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls. Rheumatology 42:123-134
16. Herman R, Mixon J, Fisher A, Maulucci R, Stuyck J (1985) Idiopathic scoliosis and the central nervous system: a motor control problem [The Harrington lecture 1983]. Scoliosis Research Society. Spine 10:1-14
17. Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, Spelsberg TC, Khosla S (1999) Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 140:4382-4389
18. Ho S, Wong E, Chan SG, Lau J, Chan C, Leung PC (1997) Determinants of peak bone mass in Chinese women aged 21-40 years. III. Physical activity and bone mineral density. J Bone Miner Res 12:1262-1271
19. Johnston CC Jr, Miller JZ, Slemenda CW, Reister TK, Hui S, Christian JC, Peacock M (1992) Calcium supplementation and increase in bone mineral density in children. New Engl J Med 327:82-87
20. Kindsfater K, Lowe T, Lawellin D, Weinstein D, Akmakjian J (1994) Levels of platelet calmodulin for the prediction of progression and severity of adolescent idiopathic scoliosis. J Bone Joint Surg 76-A:1186-1192
21. Kostenuik PJ, Bolon B, Morony S, Daris M, Geng Z, Carter C, Sheng J (2004) Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice. Bone 34:656-664
22. Machida M, Dubousset J, Imamura Y, Iwaya T, Yamada T, Kimura J, Toriyama S (1994) Pathogenesis of idiopathic scoliosis: SEPs in chicken with experimentally induced scoliosis and in patients with idiopathic scoliosis. J Pediatr Orthop 14:329-335
23. McCarrey JR, Abbott UK, Benson DR, Riggins RS (1981) Genetics of scoliosis in chickens. J Hered 72:6-10
24. Nilsson BE, Westlin NE (1971) Bone density in athletes. Clin Orthop 77:179-182
25. Rogers A, Saleh G, Hannon RA, Greenfield D, Eastell R (2002) Circulating estradiol and osteoprotegerin as determinants of bone turnover and bone density in postmenopausal women. J Clin Endocrinol Metab 87:4470-4475
26. Slemenda CW, Peacock M, Hui S, Zhou L, Johnston CC (1997) Reduced rates of skeletal remodeling are associated with increased bone mineral density the development of peak skeletal mass. J Bone Miner Res 12:676-682
27. Smith FM, Latchford G, Hall RM, Millner PA, Dickson RA (2002) Indications of disordered eating behaviour in adolescent patients with idiopathic scoliosis. J Bone Joint Surg 84-B:392-394
28. Stilwell DL Jr (1962) Structural deformities of vertebrae: Bone adaptation and modeling in experimental scoliosis and kyphosis. J Bone Joint Surg 44-A:611-634
29. Suh KT, Lee SS, Kim SJ, Kim YK, Lee JS (2007) Pineal gland metabolism in patients with adolescent idiopathic scoliosis. J Bone Joint Surg 89-B:66-71
30. Thomas KA, Cook SD, Skalley TC, Renshaw SV, Makuch RS, Gross M, Whitecloud TS 3rd, Bennett JT (1992) Lumbar spine and femoral neck bone mineral density in idiopathic scoliosis: a follow up study. J Pediatr Orthop 12:235-240
31. Wang ED, Drummond DS, Dormans JP, Moshang T, Davidson RS, Gruccio D (1997) Scoliosis in patients treated with growth hormone. J Pediatr Orthop 17:708-711