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Volumn 11, Issue 5, 2007, Pages 817-824

Purification of difluoromethylornithine by global process optimization: Coupling of chemistry and chromatography with enantioselective crystallization

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EID: 35348821459     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op700118m     Document Type: Article
Times cited : (18)

References (28)
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  • 3
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    • Bey. P, Jung, M.;2-(Difluoromethyl)-2,5-diaminopentanoic acid, U.S. Patent 4,413,141, 1982
    • Bey. P.; Jung, M.;2-(Difluoromethyl)-2,5-diaminopentanoic acid, U.S. Patent 4,413,141, 1982.
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    • Reduction of hair growth,
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    • (2004)
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    • D-Enantiomer of DFMO and methods of use therefor
    • U.S. Patent 6,602,910
    • Levenson, C.; Shaked, Z.; D-Enantiomer of DFMO and methods of use therefor, U.S. Patent 6,602,910, 2003.
    • (2003)
    • Levenson, C.1    Shaked, Z.2
  • 12
    • 35348904010 scopus 로고    scopus 로고
    • Au, A.T, Boardway, N.L, Method for the Production of, -4Difluromethyl-orthinine, U.S. Pat. 5,217,886, 1993
    • Au, A.T.; Boardway, N.L.; Method for the Production of (-)-4Difluromethyl-orthinine, U.S. Pat. 5,217,886, (1993).
  • 13
    • 84858348800 scopus 로고    scopus 로고
    • Meul, T, Process for the Preparation of, -α-(difluoromethyl) omithine monohydrochloride monohydrate, U.S. Patent 6,462,229, 2002
    • Meul, T.; Process for the Preparation of (-)-α-(difluoromethyl) omithine monohydrochloride monohydrate, U.S. Patent 6,462,229, 2002.
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    • U.S. Patent 4,330,559
    • Bey, P.; Jung, M.; Method of treating benign prostatic hypertropy, U.S. Patent 4,330,559, 1982.
    • (1982)
    • Bey, P.1    Jung, M.2
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    • Pharmaceutical Formulation Containing DFMO for the Treatment of Cancer,
    • U.S. Patent 6,277,411
    • Shaked, Z.; McGinity, J.; Pharmaceutical Formulation Containing DFMO for the Treatment of Cancer, U.S. Patent 6,277,411, 2001.
    • (2001)
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  • 22
    • 0004139082 scopus 로고
    • Collet, J. J, Wilen, S. H, Eds, Krieger Publishing Co, Malabar, FL
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    • (1994) Enantiomers, Racemates, and Resolutions
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    • In the loop: Continuous chromatography for chial (and other) separations
    • McCormick, D. In the loop: continuous chromatography for chial (and other) separations. Pharm. Technol. 2006, 30 (5), 54-68.
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    • McCormick, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.