Differential effects of soybean and fenugreek extracts on the growth of MCF-7 cells

Chemico-Biological Interactions

Volumn 170, Issue 2, 2007, Pages 135-143

  Sebastian, K S ^a   Thampan, Raghava Varman ^b  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

^b SAFI Institute of Advanced Study   (India)

Author keywords

Apoptosis; Breast cancer; Fenugreek; Flavonoids; MCF 7 cell proliferation; Phytoestrogen; Soybean

Indexed keywords

CELL DNA; FENUGREEK EXTRACT; NATURAL PRODUCT; PHYTOESTROGEN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DEGRADATION; DNA SYNTHESIS; FENUGREEK; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; SOYBEAN;

APOPTOSIS; BREAST NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; DNA, NEOPLASM; HUMANS; MEMBRANE POTENTIALS; PHOSPHATIDYLSERINES; PLANT EXTRACTS; SOYBEANS; TRIGONELLA;

GLYCINE MAX; TRIGONELLA FOENUM-GRAECUM;

EID: 35248893911     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.07.011     Document Type: Article

References (48)

1. Clemons M., and Goss P. Estrogen and the risk of breast cancer. N. Engl. J. Med. 344 (2001) 276-285
2. Yager J.D., and Davidson N.E. Estrogen carcinogenesis in breast cancer. N. Engl. J. Med. 354 (2006) 270-282
3. Branca F., and Lorenzetti S. Health effects of phytoestrogens. Forum Nutr. (2005) 100-111
4. Belcher S.M., and Zsarnovszky A. Estrogenic actions in the brain: estrogen, phytoestrogens, and rapid intracellular signaling mechanisms. J. Pharmacol. Exp. Ther. 299 (2001) 408-414
5. Albertazzi P., and Purdie D. The nature and utility of the phytoestrogens: a review of the evidence. Maturitas 42 (2002) 173-185
6. Sirtori C.R., Arnoldi A., and Johnson S.K. Phytoestrogens: end of a tale?. Ann. Med. 37 (2005) 423-438
7. Farina H.G., Pomies M., Alonso D.F., and Gomez D.E. Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer. Oncol. Rep. 16 (2006) 885-891
8. Whitsett Jr. T.G., and Lamartiniere C.A. Genistein and resveratrol: mammary cancer chemoprevention and mechanisms of action in the rat. Expert Rev. Anticancer Ther. 6 (2006) 1699-1706
9. McCann S.E., Kulkarni S., Trevisan M., Vito D., Nie J., Edge S.B., Muti P., and Freudenheim J.L. Dietary lignan intakes and risk of breast cancer by tumor estrogen receptor status. Breast Cancer Res. Treat. 99 (2006) 309-311
10. Simmen R.C., Eason R.R., Till S.R., Chatman Jr. L., Velarde M.C., Geng Y., Korourian S., and Badger T.M. Inhibition of NMU-induced mammary tumorigenesis by dietary soy. Cancer Lett. 224 (2005) 45-52
11. Dave B., Eason R.R., Till S.R., Geng Y., Velarde M.C., Badger T.M., and Simmen R.C. The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. Carcinogenesis 26 (2005) 1793-1803
12. Saarinen N.M., Power K., Chen J., and Thompson L.U. Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. Int. J. Cancer 119 (2006) 925-931
13. Bodinet C., and Freudenstein J. Influence of marketed herbal menopause preparations on MCF-7 cell proliferation. Menopause 11 (2004) 281-289
14. Allred C.D., Allred K.F., Ju Y.H., Virant S.M., and Helferich W.G. Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res. 61 (2001) 5045-5050
15. Minervini F., Giannoccaro A., Cavallini A., and Visconti A. Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters. Toxicol. Lett. 159 (2005) 272-283
16. Basch E., Ulbricht C., Kuo G., Szapary P., and Smith M. Therapeutic applications of fenugreek. Altern. Med. Rev. 8 (2003) 20-27
17. Nair S., Nagar R., and Gupta R. Antioxidant phenolics and flavonoids in common Indian foods. J. Assoc. Physicians India 46 (1998) 708-710
18. Dixit P., Ghaskadbi S., Mohan H., and Devasagayam T.P. Antioxidant properties of germinated fenugreek seeds. Phytother. Res. 19 (2005) 977-983
19. Amin A., Alkaabi A., Al-Falasi S., and Daoud S.A. Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer. Cell Biol. Int. 29 (2005) 687-694
20. Berthois Y., Katzenellenbogen J.A., and Katzenellenbogen B.S. Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 2496-2500
21. Villalobos M., Olea N., Brotons J.A., Olea-Serrano M.F., Ruiz de Almodovar J.M., and Pedraza V. The E-screen Assay: a comparison of different MCF7 cell stocks. Environ. Health Perspect. 103 (1995) 844-850
22. Smiley S.T., Reers M., Mottola-Hartshorn C., Lin M., Chen A., Smith T.W., Steele Jr. G.D., and Chen L.B. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 3671-3675
23. Lin H.H., Chen J.H., Kuo W.H., and Wang C.J. Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation. Chem. Biol. Interact. 165 (2007) 59-75
24. Rice S., and Whitehead S.A. Phytoestrogens and breast cancer-promoters or protectors?. Endocr. Relat. Cancer 13 (2006) 995-1015
25. Messina M., McCaskill-Stevens W., and Lampe J.W. Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings. J. Natl. Cancer Inst. 98 (2006) 1275-1284
26. Bouker K.B., and Hilakivi-Clarke L. Genistein: does it prevent or promote breast cancer?. Environ. Health Perspect. 108 (2000) 701-708
27. Xu W.H., Zheng W., Xiang Y.B., Ruan Z.X., Cheng J.R., Dai Q., Gao Y.T., and Shu X.O. Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study. BMJ 328 (2004) 1285
28. Chang E.T., Lee V.S., Canchola A.J., Clarke C.A., Purdie D.M., Reynolds P., Anton-Culver H., Bernstein L., Deapen D., Peel D., Pinder R., Ross R.K., Stram D.O., West D.W., Wright W., Ziogas A., and Horn-Ross P.L. Diet and risk of ovarian cancer in the California Teachers Study cohort. Am. J. Epidemiol. 165 (2007) 802-813
29. Soto A.M., Sonnenschein C., Chung K.L., Fernandez M.F., Olea N., and Serrano F.O. The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environ. Health Perspect. 103 Suppl. 7 (1995) 113-122
30. Dampier K., Hudson E.A., Howells L.M., Manson M.M., Walker R.A., and Gescher A. Differences between human breast cell lines in susceptibility towards growth inhibition by genistein. Br. J. Cancer 85 (2001) 618-624
31. de Lemos M.L. Effects of soy phytoestrogens genistein and daidzein on breast cancer growth. Ann. Pharmacother. 35 (2001) 1118-1121
32. Hsieh C.Y., Santell R.C., Haslam S.Z., and Helferich W.G. Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res. 58 (1998) 3833-3838
33. Nakagawa H., Yamamoto D., Kiyozuka Y., Tsuta K., Uemura Y., Hioki K., Tsutsui Y., and Tsubura A. Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines. J. Cancer Res. Clin. Oncol. 126 (2000) 448-454
34. Gallo D., Ferlini C., Fabrizi M., Prislei S., and Scambia G. Lack of stimulatory activity of a phytoestrogen-containing soy extract on the growth of breast cancer tumors in mice. Carcinogenesis 27 (2006) 1404-1409
35. Kuiper G.G., Lemmen J.G., Carlsson B., Corton J.C., Safe S.H., van der Saag P.T., van der Burg B., and Gustafsson J.A. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 139 (1998) 4252-4263
36. Akiyama T., Ishida J., Nakagawa S., Ogawara H., Watanabe S., Itoh N., Shibuya M., and Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262 (1987) 5592-5595
37. Traganos F., Ardelt B., Halko N., Bruno S., and Darzynkiewicz Z. Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. Cancer Res. 52 (1992) 6200-6208
38. Matsukawa Y., Marui N., Sakai T., Satomi Y., Yoshida M., Matsumoto K., Nishino H., and Aoike A. Genistein arrests cell cycle progression at G2-M. Cancer Res. 53 (1993) 1328-1331
39. Higashi K., and Ogawara H. Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim. Biophys. Acta 1221 (1994) 29-35
40. Brooks J.D., and Thompson L.U. Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells. J. Steroid Biochem. Mol. Biol. 94 (2005) 461-467
41. Jeong H.J., Shin Y.G., Kim I.H., and Pezzuto J.M. Inhibition of aromatase activity by flavonoids. Arch. Pharm. Res. 22 (1999) 309-312
42. Lacey M., Bohday J., Fonseka S.M., Ullah A.I., and Whitehead S.A. Dose-response effects of phytoestrogens on the activity and expression of 3beta-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells. J. Steroid Biochem. Mol. Biol. 96 (2005) 279-286
43. Le Bail J.C., Laroche T., Marre-Fournier F., and Habrioux G. Aromatase and 17beta-hydroxysteroid dehydrogenase inhibition by flavonoids. Cancer Lett. 133 (1998) 101-106
44. Sanderson J.T., Hordijk J., Denison M.S., Springsteel M.F., Nantz M.H., and van den Berg M. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol. Sci. 82 (2004) 70-79
45. Kao Y.C., Zhou C., Sherman M., Laughton C.A., and Chen S. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: a site-directed mutagenesis study. Environ. Health Perspect. 106 (1998) 85-92
46. King R.A., and Bursill D.B. Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans. Am. J. Clin. Nutr. 67 (1998) 867-872
47. Van Patten C.L., Olivotto I.A., Chambers G.K., Gelmon K.A., Hislop T.G., Templeton E., Wattie A., and Prior J.C. Effect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: a randomized, controlled clinical trial. J. Clin. Oncol. 20 (2002) 1449-1455
48. De Lemos M. Safety issues of soy phytoestrogens in breast cancer patients. J. Clin. Oncol. 20 (2002) 3040-3041 (author reply 3041-3042)