The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy

European Journal of Medicinal Chemistry

Volumn 38, Issue 5, 2003, Pages 451-457

  Verrax, Julien ^a   Cadrobbi, Julie ^a   Delvaux, Marianne ^a   Jamison, James M ^b   Gilloteaux, Jacques ^b   Summers, Jack L ^b   Taper, Henryk S ^a   Buc Calderon, Pedro ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b SUMMA HEALTH SYSTEM   (United States)

Author keywords

Autoschizis; Cancer; Oxidative stress; Vitamins C and K3

Indexed keywords

2,3 DIMETHOXY NAPHTHOQUINONE; ANTINEOPLASTIC AGENT; ASCORBIC ACID; CASPASE 3; DNA FRAGMENT; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MENADIONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; AUTOSCHIZIS; CANCER ADJUVANT THERAPY; CANCER CELL DESTRUCTION; CELL DEATH; CELL KILLING; CELL ORGANELLE; CYTOTOXICITY TEST; DRUG MECHANISM; DRUG OXIDATION; DRUG POTENCY; DRUG POTENTIATION; ENZYME ACTIVATION; HISTOPATHOLOGY; IN VIVO STUDY; MEMBRANE DAMAGE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0037722974     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(03)00082-5     Document Type: Review

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