Contractile and connective tissue protein content of human skeletal muscle: Effects of 35 and 90 days of simulated microgravity and exercise countermeasures

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 293, Issue 4, 2007, Pages

  Haus, Jacob M ^a   Carrithers, John A ^b   Carroll, Chad C ^a,b   Tesch, Per A ^b,c   Trappe, Todd A ^a,b  

^a BALL STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Actin; Bed rest; Collagen; Myosin; Resistance exercise; Spaceflight

Indexed keywords

ACTIN; COLLAGEN; CONTRACTILE PROTEIN; MUSCLE PROTEIN; MYOSIN;

ADULT; ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; MICROGRAVITY; MUSCLE BIOPSY; MUSCLE EXERCISE; MUSCLE FUNCTION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; QUADRICEPS FEMORIS MUSCLE; SIMULATION; SKELETAL MUSCLE; SOLEUS MUSCLE; TRICEPS SURAE MUSCLE; VASTUS LATERALIS MUSCLE; WEIGHTLESSNESS;

ADULT; CONNECTIVE TISSUE; CONTRACTILE PROTEINS; EXERCISE; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MUSCULAR ATROPHY; TIME FACTORS; WEIGHTLESSNESS SIMULATION;

EID: 35148851555     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00292.2007     Document Type: Article

References (45)

1. Alkner BA, Tesch PA. Efficacy of a gravity-independent resistance exercise device as a countermeasure to muscle atrophy during 29-day bed rest. Acta Physiol Scand 181: 345-357, 2004.
2. Alkner BA, Tesch PA. Knee extensor and plantar flexor muscle size and function following 90 days of bed rest with or without resistance exercise. Eur J Appl Physiol 93: 294-305, 2004.
3. Arruda EM, Mundy K, Calve S, Baar K. Denervation does not change the ratio of collagen I and collagen III mRNA in the extracellular matrix of muscle. Am J Physiol Regul Integr Comp Physiol 292: R983-R987, 2007.
4. Baldwin KM, Caiozzo VJ, Haddad F, Baker MJ, Herrick RE. The effects of space flight on the contractile apparatus of antigravity muscles: implications for aging and deconditioning. J Gravit Physiol 1: P8-P11, 1994.
5. Baldwin KM, Herrick RE, Ilyina-Kakueva E, Oganov VS. Effects of zero gravity on myofibril content and isomyosin distribution in rodent skeletal muscle. FASEB J 4: 79-83, 1990.
6. Baldwin KM, White TP, Arnaud SB, Edgerton VR, Kraemer WJ, Kram R, Raab-Cullen D, Snow CM. Musculoskeletal adaptations to weightlessness and development of effective countermeasures. Med Sci Sports Exerc 28: 1247-1253, 1996.
7. Bamman MM, Hunter GR, Stevens BR, Guilliams ME, Greenisen MC. Resistance exercise prevents plantar flexor deconditioning during bed rest. Med Sci Sports Exerc 29: 1462-1468, 1997.
8. Berg HE, Dudley GA, Haggmark T, Ohlsen H, Tesch PA. Effects of lower limb unloading on skeletal muscle mass and function in humans. J Appl Physiol 70: 1882-1885, 1991.
9. Bergstrom J. Muscle electrolytes in man. Scand J Clin Lab Invest Suppl 68: 1-110, 1962.
10. Chi MM, Hintz CS, Coyle EF, Martin WH, 3rd Ivy JL, Nemeth PM, Holloszy JO, Lowry OH. Effects of detraining on enzymes of energy metabolism in individual human muscle fibers. Am J Physiol Cell Physiol 244: C276-C287, 1983.
11. Edgerton VR, Roy RR. Neuromuscular adaptations to actual and simulated spaceflight. In: Handbook of Physiology, Section 4: Environmental Physiology, edited by Fregly M and Blatteis C. New York: Oxford Press, 1996, p. 721-763.
12. Eyre DR, Koob TJ, Van Ness KP. Quantitation of hydroxypyridinium crosslinks in collagen by high-performance liquid chromatography. Anal Biochem 137: 380-388, 1984.
13. Fitts RH, Riley DR, Widrick JJ. Physiology of a microgravity environment invited review: microgravity and skeletal muscle. J Appl Physiol 89: 823-839, 2000.
14. Fortney S, Schneider V, Greenleaf JE. The physiology of bed rest. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol. II, chapt. 39, p. 889-939.
15. Gineyts E, Cloos PA, Borel O, Grimaud L, Delmas PD, Garnero P. Racemization and isomerization of type I collagen C-telopeptides in human bone and soft tissues: assessment of tissue turnover. Biochem J 345: 481-485, 2000.
16. Giulian GG, Moss RL, Greaser M. Improved methodology for analysis and quantitation of proteins on one-dimensional silver-stained slab gels. Anal Biochem 129: 277-287, 1983.
17. Gosselin LE, Adams C, Cotter TA, McCormick RJ, Thomas DP. Effect of exercise training on passive stiffness in locomotor skeletal muscle: role of extracellular matrix. J Appl Physiol 85: 1011-1016, 1998.
18. Haddad F, Herrick RE, Adams GR, Baldwin KM. Myosin heavy chain expression in rodent skeletal muscle: effects of exposure to zero gravity. J Appl Physiol 75: 2471-2477, 1993.
19. Hutson PR, Crawford ME, Sorkness RL. Liquid chromatographic determination of hydroxyproline in tissue samples. J Chromatogr B Biomed Appl 791: 427-430, 2003.
20. Ingalls CP, Warren GL, Armstrong RB. Dissociation of force production from MHC and actin contents in muscles injured by eccentric contractions. J Muscle Res Cell Motil 19: 215-224, 1998.
21. Kasper CE, Xun L. Expression of titin in skeletal muscle varies with hind-limb unloading. Biol Res Nurs 2: 107-115, 2000.
22. Kjaer M. Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading. Physiol Rev 84: 649-698, 2004.
23. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
24. LeBlanc A, Lin C, Shackelford L, Sinitsyn V, Evans H, Belichenko O, Schenkman B, Kozlovskaya I, Oganov V, Bakulin A, Hedrick T, Feeback D. Muscle volume, MRI relaxation times (T2), and body composition after spaceflight. J Appl Physiol 89: 2158-2164, 2000.
25. Martin TP. Protein and collagen content of rat skeletal muscle following space flight. Cell Tissue Res 254: 251-253, 1988.
26. Miller BF, Olesen JL, Hansen M, Dossing S, Crameri RM, Welling RJ, Langberg H, Flyvbjerg A, Kjaer M, Babraj JA, Smith K, Rennie MJ. Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise. J Physiol 567: 1021-1033, 2005.
27. Miller TA, Lesniewski LA, Muller-Delp JM, Majors AK, Scalise D, Delp MD. Hindlimb unloading induces a collagen isoform shift in the soleus muscle of the rat. Am J Physiol Regul Integr Comp Physiol 281: R1710-R1717, 2001.
28. Patel TJ, Lieber RL. Force transmission in skeletal muscle: from actomyosin to external tendons. Exerc Sport Sci Rev 25: 321-363, 1997.
29. Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL. Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight. J Appl Physiol 88: 567-572, 2000.
30. Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL. Disproportionate loss of thin filaments in human soleus muscle after 17-day bed rest. Muscle Nerve 21: 1280-1289, 1998.
31. Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL. Thin filament diversity and physiological properties of fast and slow fiber types in astronaut leg muscles. J Appl Physiol 92: 817-825, 2002.
32. Riley DA, Thompson JL, Krippendorf BB, Slocum GR. Review of spaceflight and hindlimb suspension unloading induced sarcomere damage and repair. Basic Appl Myol 5: 139-145, 1995.
33. Schulze K, Gallagher P, Trappe S. Resistance training preserves skeletal muscle function during unloading in humans. Med Sci Sports Exerc 34: 303-313, 2002.
34. Shackelford LC, LeBlanc AD, Driscoll TB, Evans HJ, Rianon NJ, Smith SM, Spector E, Feeback DL, Lai D. Resistance exercise as a countermeasure to disuse-induced bone loss. J Appl Physiol 97: 119-129, 2004.
35. Solaro RJ, Pang DC, Briggs FN. The purification of cardiac myofibrils with Triton X-100. Biochim Biophys Acta 245: 259-262, 1971.
36. Steffen JM, Musacchia XJ. Spaceflight effects on adult rat muscle protein, nucleic acids, and amino acids. Am J Physiol Regul Integr Comp Physiol 251: R1059-R1063, 1986.
37. Tesch PA, Ekberg A, Lindquist DM, Trieschmann JT. Muscle hypertrophy following 5-week resistance training using a non-gravity-dependent exercise system. Acta Physiol Scand 180: 89-98, 2004.
38. Tesch PA, Trieschmann JT, Ekberg A. Hypertrophy of chronically unloaded muscle subjected to resistance exercise. J Appl Physiol 96: 1451-1458, 2004.
39. Toursel T, Stevens L, Granzier H, Mounier Y. Passive tension of rat skeletal soleus muscle fibers: effects of unloading conditions. J Appl Physiol 92: 1465-1472, 2002.
40. Trappe S, Gallagher P, Harber M, Carrithers J, Fluckey J, Trappe T. Single muscle fibre contractile properties in young and old men and women. J Physiol 552: 47-58, 2003.
41. Trappe SW, Trappe TA, Lee GA, Widrick JJ, Costill DL, Fitts RH. Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function. J Appl Physiol 91: 57-64, 2001.
42. Trappe TA, Lindquist DM, Carrithers JA. Muscle-specific atrophy of the quadriceps femoris with aging. J Appl Physiol 90: 2070-2074, 2001.
43. Tsika RW, Herrick RE, Baldwin KM. Time course adaptations in rat skeletal muscle isomyosins during compensatory growth and regression. J Appl Physiol 63: 2111-2121, 1987.
44. Urso ML, Scrimgeour AG, Chen YW, Thompson PD, Clarkson PM. Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components. J Appl Physiol 101: 1136-1148, 2006.
45. Zange J, Muller K, Schuber M, Wackerhage H, Hoffmann U, Gunther RW, Adam G, Neuerburg JM, Sinitsyn VE, Bacharev AO, Belichenko OI. Changes in calf muscle performance, energy metabolism, and muscle volume caused by long-term stay on space station MIR. Int J Sports Med 18 Suppl 4: S308-S309, 1997.