Mechanical response and conformational changes of alpha-actinin domains during unfolding: A molecular dynamics study

Biomechanics and Modeling in Mechanobiology

Volumn 6, Issue 6, 2007, Pages 399-407

  Soncini, Monica ^a   Vesentini, Simone ^a   Ruffoni, Davide ^b   Orsi, Mario ^c   Deriu, Marco A ^d   Redaelli, Alberto ^a  

^a POLITECNICO DI MILANO   (Italy)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d POLITECNICO DI TORINO   (Italy)

Author keywords

Alpha actinin; Mechanical unfolding; Molecular dynamics

Indexed keywords

MOLECULAR DYNAMICS; MUSCLE; SENSITIVITY ANALYSIS; SOLVENTS; STIFFNESS;

ALPHA ACTININ; CYTOSKELETON BINDING PROTEIN; MECHANICAL UNFOLDING;

PROTEINS;

ACTININ; SOLVENT;

ARTICLE; ATOMIC FORCE MICROSCOPY; BIOMECHANICS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; METABOLISM; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; ULTRASTRUCTURE;

ACTININ; BIOMECHANICS; COMPUTER SIMULATION; DIMERIZATION; HUMANS; HYDROGEN BONDING; HYDROPHOBICITY; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 35148849551     PISSN: 16177959     EISSN: 16822978     Source Type: Journal    
DOI: 10.1007/s10237-006-0060-z     Document Type: Article

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