Gastrointestinal stromal tumors of the rectum: Clinical, pathologic, immunohistochemical characteristics and prognostic analysis

Scandinavian Journal of Gastroenterology

Volumn 42, Issue 10, 2007, Pages 1221-1229

  Dong, Chen ^a   Jun Hui, Cui ^a   Xiao Jun, Yang ^a   Mei, Kong ^a   Bo, Wang ^a   Chen Fei, Jiang ^a   Wei Li, Yang ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

CD117; Gastrointestinal stromal tumors (GISTs); Metastasis; Rectal; Recurrence

Indexed keywords

CD34 ANTIGEN; PROTEIN S 100; SMOOTH MUSCLE ACTIN; STEM CELL FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER SURGERY; CLINICAL ARTICLE; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; GASTROINTESTINAL STROMAL TUMOR; HEALTH CARE ORGANIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LAPAROTOMY; MALE; METASTASIS; MUCOSA; NECROSIS; OUTCOME ASSESSMENT; PATHOLOGY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; RECTUM TUMOR; RECURRENT DISEASE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEROSA; SURVIVAL TIME; TIME SERIES ANALYSIS; UNIVARIATE ANALYSIS;

ADULT; AGED; FEMALE; GASTROINTESTINAL STROMAL TUMORS; HUMANS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MITOSIS; NECROSIS; NEOPLASM METASTASIS; PROGNOSIS; RECTAL NEOPLASMS; RECURRENCE; SURVIVAL ANALYSIS; SURVIVORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 35148839178     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520701376507     Document Type: Article

References (27)

1. Blay JY, Le Cesne A, Verweij J, Scurr M, Seynaeve C, Bonvalot S, et al. A phase II study of ET-743/trabectedin ("Yondelis") for patients with advanced gastrointestinal stromal tumours. Eur J Cancer 2004;40:1327-31.
2. Tran T, Davila JA, EI-Serag HB. The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000. Am J Gastroenterol 2005;100:162-8.
3. Miettinen M, Furlong M, Sarlomo-Rikala M, Burke A, Sobin LH, Lasota J. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J Surg Pathol 2001;25:1121-33.
4. Emory TS, Sobin LH, Lukes L, Lee DH, O'Leary TJ. Prognosis of gastrointestinal smooth-muscle (stromal) tumours: dependence on anatomic site. Am J Surg Pathol 1999;23:82-7.
5. Antonescu CR, Viale A, Sarran L, Tschernyavsky SJ, Gonen M, Segal NH, et al. Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site. Clin Cancer Res 2004;10:3282-90.
6. Wasag B, Debiec-Rychter M, Pauwels P, Stul M, Vranckx H, Oosterom AV, et al. Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site. Mod Pathol 2004;17:889-94.
7. Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Mod Pathol 2000;13:1134-42.
8. Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002;33:459-65.
9. Mazur MT, Clark HB. Gastric stromal tumors: reappraisal of histogenesis. Am J Surg Pathol 1983;7:507-19.
10. Connolly EM, Gaffney E, Reynolds JV. Gastrointestinal stromal tumours. Br J Surg 2003;90:1178-86.
11. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998;279:577-80.
12. Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 2003;21:4342-9.
13. Roberts PJ, Eisenberg B. Clinical presentation of gastrointestinal stromal tumors and treatment of operable disease. Eur J Cancer 2002;38(Suppl):S37-8.
14. Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, et al. Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database. Ann Surg Oncol 2001;8:50-9.
15. DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg 2000;231:51-8.
16. Eisenberg B, Judson I. Surgery and imatinib in the management of GIST: emerging approaches to adjuvant and neoadjuvant therapy. Ann Surg Oncol 2004;11:465-75.
17. Joensuu H, Fletcher C, Dimitrijevic S, Silberman S, Roberts P, Demetri G. Management of malignant gastrointestinal stromal tumours. Lancet Oncol 2002;3:655-64.
18. Richmond JA, Mount SL, Schwarz JE. Gastrointestinal stromal tumor of the stomach with rhabdoid phenotype: immunohistochemical, ultrastructural, and immunoelectron microscopic evaluation. Ultrastruct Pathol 2004;28:165-70.
19. Lo SS, Papachristou GI, Finkelstein SD, Conroy WP, Schraut WH, Ramanathan RK. Neoadjuvant imatinib in gastrointestinal stromal tumor of the rectum: report of a case. Dis Colon Rectum 2005;48:1316-9.
20. Levy AD, Remotti HE, Thompson WM, Sobin LH, Miettinen M. Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics 2003;23:283-304.
21. Blay JY, Bonvalot S, Casali P, Choi H, Debiec-Richter M, Dei Tos AP, et al. Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Ann Oncol 2005;16:566-78.
22. Changchien CR, Wu MC, Tasi WS, Tang R, Chiang JM, Chen JS, et al. Evaluation of prognosis for malignant rectal gastrointestinal stromal tumor by clinical parameters and immunohistochemical staining. Dis Colon Rectum 2004;47:1922-9.
23. Goldblum JR, Appelman HD. Stromal tumors of the duodenum: a histologic and immunohistochemical study of 20 cases. Am J Surg Pathol 1995;19:71-80.
24. Brainard JA, Goldblum JR. Stromal tumors of jejunum and ileum: a clinicopathologic study of 39 cases. Am J Surg Pathol 1997;21:407-16.
25. Tworek JA, Appelman HD, Singleton TP, Greenson JK. Stromal tumors of jejunum and ileum. Mod Pathol 1997;10:200-9.
26. Schneider-Stock R, Boltze C, Lasota J, Peters B, Corless CL, Ruennete P, et al. Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study. Clin Cancer Res 2005;11:638-45.
27. Dei Tos AP. The reappraisal of gastrointestinal stromal tumors: from Stout to the KIT revolution. Virchows Arch 2003;442:421-8.