Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential ligands with 5-HT1A binding affinity

Synthetic Communications

Volumn 37, Issue 20, 2007, Pages 3559-3567

  Pessoa Mahana, Hernán ^a   Acevedo, R ^a   Araya Maturana, Ramiro ^a   Saitz, Claudio ^a   Pessoa Mahana, C David ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

5 HT1A; Arylpiperazines; Benzothiophene; Depression

Indexed keywords

4,7 DIMETHOXY N [2 [(4 PHENYL 1 PIPERAZINYL)METHYL]PHENYL]BENZO[B]THIOPHENE 2 CARBOXAMIDE; 4,7 DIMETHOXY N [2 [[4 (2 METHOXYPHENYL) 1 PIPERAZINYL]METHYL]PHENYL] 1 BENZO[B]THIOPHENE 2 CARBOXAMIDE; 4,7 DIMETHOXY N [2 [[4 (2 PYRIDINYL) 1 PIPERAZINYL]METHYL]PHENYL] 1 BENZO[B]THIOPHENE 2 CARBOXAMIDE; 4,7 DIMETHOXY N [2 [[4 (4 NITROPHENYL) 1 PIPERAZINYL]METHYL]PHENYL] 1 BENZO[B]THIOPHENE 2 CARBOXAMIDE; AMIDE; BENZOTHIOPHENE DERIVATIVE; N [2 (CHLOROMETHYL)PHENYL] 4,7 DIMETHOXYBENZO[B]THIOPHENE 2 CARBOXAMIDE; N [2 [[4 (2 FLUOROPHENYL) 1 PIPERAZINYL]METHYL]PHENYL] 4,7 DIMETHOXIBENZO[B]THIOPHENE 2 CARBOXAMIDE; N [2 [[4 (4 FLUOROPHENYL) 1 PIPERAZINYL]METHYL]PHENYL] 4,7 DIMETHOXIBENZO[B]THIOPHENE 2 CARBOXAMIDE; PIPERAZINE DERIVATIVE; SEROTONIN 1 AGONIST; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; RECEPTOR AFFINITY; SUBSTITUTION REACTION;

EID: 35148832705     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910701557499     Document Type: Article

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