Prognostic significance of pathologic nodal status in patients with resected pancreatic cancer

Journal of Gastrointestinal Surgery

Volumn 11, Issue 11, 2007, Pages 1549-1555

  House, Michael G ^a   Gönen, Mithat ^a   Jarnagin, William R ^a   D'Angelica, Michael ^a   Dematteo, Ronald P ^a   Fong, Yuman ^a   Brennan, Murray F ^a   Allen, Peter J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Adenocarcinoma; Lymph nodes; Pancreas; Survival

Indexed keywords

ADENOCARCINOMA; ADULT; AGED; ARTICLE; HUMAN; LYMPH NODE; LYMPH NODE METASTASIS; MALE; MIDDLE AGED; MORTALITY; PANCREAS TUMOR; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 35148826561     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-007-0243-7     Document Type: Article

References (28)

1. DiMagno EP, Reber HA, Tempero MA. AGA technical review on the epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. American Gastroenterological Association. Gastroenterology 1999;117(6):1464- 1484.
2. Neoptolemos JP, Russell RC, Bramhall S, Theis B. Low mortality following resection for pancreatic and periampullary tumours in 1026 patients: UK survey of specialist pancreatic units. UK Pancreatic Cancer Group. Br J Surg 1997;84(10):1370-1376.
3. Howard TJ, Krug JE, Yu J, et al. A margin-negative R0 resection accomplished with minimal postoperative complications is the surgeon's contribution to long-term survival in pancreatic cancer. J Gastrointest Surg 2006;10(10):1338-1345;discussion 1345-1346.
4. Cleary SP, Gryfe R, Guindi M et al. Prognostic factors in resected pancreatic adenocarcinoma: analysis of actual 5-year survivors. J Am Coll Surg 2004;198(5):722-731.
5. Cameron JL. Long-term survival following pancreaticoduodenectomy for adenocarcinoma of the head of the pancreas. Surg Clin North Am 1995;75(5):939-951.
6. Conlon KC, Klimstra DS, Brennan MF. Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors. Ann Surg 1996;223(3):273-279.
7. Winter JM, Cameron JL, Campbell KA, et al. 1423 pancreaticoduodenectomies for pancreatic cancer: a single-institution experience. J Gastrointest Surg 2006;10(9):1199-1210; discussion 1210-1211.
8. Brennan MF, Kattan MW, Klimstra D, Conlon K. Prognostic nomogram for patients undergoing resection for adenocarcinoma of the pancreas. Ann Surg 2004;240(2):293-298.
9. Geer RJ, Brennan MF. Prognostic indicators for survival after resection of pancreatic adenocarcinoma. Am J Surg 1993;165(1):68-72; discussion 72-73.
10. Lim JE, Chien MW, Earle CC. Prognostic factors following curative resection for pancreatic adenocarcinoma: a population-based, linked database analysis of 396 patients. Ann Surg 2003;237(1):74-85.
11. Schwarz RE, Smith DD. Extent of lymph node retrieval and pancreatic cancer survival: information from a large US population database. Ann Surg Oncol 2006;13(9):1189-1200.
12. Pawlik TM, Gleisner AL, Cameron JL, et al. Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer. Surgery 2007;141(5):610-618.
13. Berger AC, Watson JC, Ross EA, Hoffman JP. The metastatic/examined lymph node ratio is an important prognostic factor after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am Surg 2004;70(3):235-240; discussion 240.
14. Sierzega M, Popiela T, Kulig J, Nowak K. The ratio of metastatic/resected lymph nodes is an independent prognostic factor in patients with node-positive pancreatic head cancer. Pancreas 2006;33(3):240-245.
15. AJCC. AJCC Cancer Staging Manual, 6th ed. New York, NY: Springer, 2002.
16. Miller RG Jr. What price Kaplan-Meier? Biometrics 1983;39(4):1077-1081.
17. Miller RG, Jr. What price Kaplan-Meier? Biometrics 1983;39(4):1077-1081.
18. Sohn TA, Yeo CJ, Cameron JL, et al. Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators. J Gastrointest Surg 2000;4(6):567-579.
19. Yeo CJ, Cameron JL, Sohn TA, et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 1997;226(3):248-257; discussion 257-260.
20. Gazzaniga GM, Cappato S, Papadia F, et al. D1 versus D2 pancreatoduodenectomy in surgical therapy of pancreatic head cancer. Hepatogastroenterology 2001;48(41):1471-1478.
21. Henne-Bruns D, Vogel I, Luttges J, et al. Surgery for ductal adenocarcinoma of the pancreatic head: staging, complications, and survival after regional versus extended lymphadenectomy. World J Surg 2000;24(5):595-601; discussion 601-602.
22. Pedrazzoli S, DiCarlo V, Dionigi R, et al. Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas: a multicenter, prospective, randomized study. Lymphadenectomy Study Group. Ann Surg 1998;228(4):508-517.
23. Yeo CJ, Cameron JL, Lillemoe KD, et al. Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality. Ann Surg 2002;236(3):355-366; discussion 366-368.
24. Sierra A, Regueira FM, Hernandez-Lizoain JL, et al. Role of the extended lymphadenectomy in gastric cancer surgery: experience in a single institution. Ann Surg Oncol 2003;10(3):219-226.
25. Berger AC, Sigurdson ER, LeVoyer T, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol 2005;23(34):8706-8712.
26. Barbour AP, Rizk NP, Gonen M, et al. Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): impact of adequate staging on outcome. Ann Surg Oncol 2007;14(2):306-316.
27. Ishikawa O, Ohigashi H, Sasaki Y, et al. Practical grouping of positive lymph nodes in pancreatic head cancer treated by an extended pancreatectomy. Surgery 1997;121(3):244-249.
28. Hermanek P. Staging of exocrine pancreatic carcinoma. Eur J Surg Oncol 1991;17(2):167-172.