Inactivation of an iron transporter in Lactococcus lactis results in resistance to tellurite and oxidative stress

Applied and Environmental Microbiology

Volumn 73, Issue 19, 2007, Pages 6144-6149

  Turner, Mark S ^a,b   Yu, Pei Tan ^a   Giffard, Philip M ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

IRON TRANSPORTER; METAL METABOLISM; OXIDATIVE DEFENSE; RESPIRATORY METABOLISM;

GENES; IRON; METABOLISM; MUTAGENESIS; OXIDATIVE STRESS; PH;

BACTERIA;

CARRIER PROTEIN; FERRIC ION; IRON TRANSPORTER; OXYGEN; PROTEIN MNTH; TELLURITE; TELLURIUM DERIVATIVE; UNCLASSIFIED DRUG;

BACTERIUM; FREE RADICAL; METABOLISM; MUTATION; OXIDATION;

ARTICLE; BACTERIAL METABOLISM; BACTERIAL SURVIVAL; BACTERIUM MUTANT; IRON METABOLISM; IRON TRANSPORT; LACTOCOCCUS LACTIS; NONHUMAN; OXIDATIVE STRESS; OXYGEN TOXICITY; PH;

BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; IRON; LACTOCOCCUS LACTIS; MULTIENZYME COMPLEXES; OXIDATIVE STRESS; OXYGEN; TELLURIUM;

LACTOCOCCUS LACTIS;

EID: 35148818329     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.00413-07     Document Type: Article

References (31)

1. Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
2. Duwat, P., S. D. Ehrlich, and A. Gruss. 1995. The recA gene of Lactococcus lactis: characterization and involvement in oxidative and thermal stress. Mol. Microbiol. 17:1121-1131.
3. Duwat, P., S. D. Ehrlich, and A. Gruss. 1999. Effects of metabolic flux on stress response pathways in Lactococcus lactis. Mol. Microbiol. 31:845-858.
4. Duwat, P., S. Sourice, B. Cesselin, G. Lamberet, K. Vido, P. Gaudu, Y. Le Loir, F. Violet, P. Loubiere, and A. Gruss. 2001. Respiration capacity of the fermenting bacterium Lactococcus lactis and its positive effects on growth and survival. J. Bacteriol. 183:4509-4516.
5. Fraser, K. R., D. Harvie, P. J. Coote, and C. P. O'Byrne. 2000. Identification and characterization of an ATP binding cassette L-carnitine transporter in Listeria monocytogenes. Appl. Environ. Microbiol. 66:4696-4704.
6. Frees, D., P. Varmanen, and H. Ingmer. 2001. Inactivation of a gene that is highly conserved in Gram-positive bacteria stimulates degradation of non-native proteins and concomitantly increases stress tolerance in Lactococcus lactis. Mol. Microbiol. 41:93-103.
7. Gaudu, P., G. Lamberet, S. Poncet, and A. Gruss. 2003. CcpA regulation of aerobic and respiration growth in Lactococcus lactis. Mol. Microbiol. 50:183-192.
8. Groot, M. N., E. Klaassens, W. M. de Vos, J. Delcour, P. Hols, and M. Kleerebezem. 2005. Genome-based in silico detection of putative manganese transport systems in Lactobacillus plantarum and their genetic analysis. Microbiology 151:1229-1238.
9. Harwood, C. R., and S. M. Cutting. 1990. Molecular biological methods for Bacillus. John Wiley and Sons, Ltd., Chichester, England.
10. Hayashi, N., M. Ito, S. Horiike, and H. Taguchi. 2001. Molecular cloning of a putative divalent-cation transporter gene as a new genetic marker for the identification of Lactobacillus brevis strains capable of growing in beer. Appl. Microbiol. Biotechnol. 55:596-603.
11. Huston, W. M., M. P. Jennings, and A. G. McEwan. 2002. The multicopper oxidase of Pseudomonas aeruginosa is a ferroxidase with a central role in iron acquisition. Mol. Microbiol. 45:1741-1750.
12. Kehres, D. G., M. L. Zaharik, B. B. Finlay, and M. E. Maguire. 2000. The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen. Mol. Microbiol. 36:1085-1100.
13. Maguin, E., H. Prevost, S. D. Ehrlich, and A. Gruss. 1996. Efficient insertional mutagenesis in lactococci and other gram-positive bacteria. J. Bacteriol. 178:931-935.
14. Reference deleted.
15. Makui, H., E. Roig, S. T. Cole, J. D. Helmann, P. Gros, and M. F. M. Cellier. 2000. Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter. Mol. Microbiol. 35:1065-1078.
16. Nakano, S., E. Kuster-Schock, A. D. Grossman, and P. Zuber. 2003. Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 100:13603-13608.
17. Reference deleted.
18. Perez, J. M., I. L. Calderon, F. A. Arenas, D. E. Fuentes, G. A. Pradenas, E. L. Fuentes, J. M. Sandoval, M. E. Castro, A. O. Elias, and C. C. Vasquez. 2007. Bacterial toxicity of potassium tellurite: unveiling an ancient enigma. PLoS ONE 2:e211.
19. Rallu, F., A. Gruss, S. D. Ehrlich, and E. Maguin. 2000. Acid- and multi-stress-resistant mutants of Lactococcus lactis: identification of intracellular stress signals. Mol. Microbiol. 35:517-528.
20. Rezaïki, L., B. Cesselin, Y. Yamamoto, K. Vido, E. van West, P. Gaudu, and A. Gruss. 2004. Respiration metabolism reduces oxidative and acid stress to improve long-term survival of Lactococcus lactis. Mol. Microbiol. 53:1331-1342.
21. Richer, E., P. Courville, I. Bergevin, and M. F. M. Cellier. 2003. Horizontal gene transfer of "prototype" Nramp in bacteria. J. Mol. Evol. 57:363-376.
22. Sanders, J. W., K. J. Leenhouts, A. J. Haandrikman, G. Venema, and J. Kok. 1995. Stress response in Lactococcus lactis: cloning, expression analysis, and mutation of the lactococcal superoxide dismutase gene. J. Bacteriol. 177: 5254-5260.
23. Sleator, R. D., J. Wouters, C. G. Gahan, T. Abee, and C. Hill. 2001. Analysis of the role of OpuC, an osmolyte transport system, in salt tolerance and virulence potential of Listeria monocytogenes. Appl. Environ. Microbiol. 67: 2692-2698.
24. Stookey, L. L. 1970. Ferrozine: a new spectrophotometric reagent for iron. Anal. Chem. 42:779-781.
25. Taylor, D. E. 1999. Bacterial tellurite resistance. Trends Microbiol. 7:111-115.
26. Tremaroli, V., F. Stefano, and D. Zannoni. 2007. Evidence for a tellurite-dependent generation of reactive oxygen species and absence of a tellurite-mediated adaptive response to oxidative stress of cells of Pseudomonas pseudoalcaligenes KF707. Arch. Microbiol. 187:127-135.
27. Turner, M. S., R. Lo, and P. M. Giffard. 2007. Inhibition of Staphylococcus aureus growth on tellurite-containing media by Lactobacillus reuteri is dependent upon CyuC and thiol production. Appl. Environ. Microbiol. 73: 1005-1009.
28. Veiga, P., C. Bulbarela-Sampieri, S. Furlan, A. Maisons, M. P. Chapot-Chartier, M. Erkelenz, P. Mervelet, P. Noirot, D. Frees, O. Kuipers, J. Kok, A. Gruss, G. Buist, and S. Kulakauskas. 7 May 2007. SpxB regulates O-acetylation dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis. J. Biol. Chem. [Epub ahead of print.]
29. Vido, K., H. Diemer, A. van Dorsselaer, E. Leize, V. Juillard, A. Gruss, and P. Gaudu. 2005. Roles of thioredoxin reductase during the aerobic life of Lactococcus lactis. J. Bacteriol. 187:601-610.
30. Viollier, E., P. W. Inglett, K. Hunter, A. N. Roychoudhury, and P. van Cappellen. 2000. The ferrozine method revisited: Fe(II)/Fe(III) determination in natural waters. Appl. Geochem. 15:785-790.
31. Wegmann, U., M. O'Connell-Motherway, A. Zomer, G. Buist, C. Shearman, C. Canchaya, M. Ventura, A. Goesmann, M. J. Gasson, O. P. Kuipers, D. van Sinderen, and J. Kok. 2007. Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363. J. Bacteriol. 189:3256-3270.