Non-organ-specific autoantibodies and cmv infection in renal transplant recipients with or without rejection

Transplantationsmedizin: Organ der Deutschen Transplantationsgesellschaft

Volumn 19, Issue 2, 2007, Pages 39-43

  Costa, Cristina ^a   Bergallo, M ^a   Touscoz, G A ^b   Margio, S ^a   Sidoti, F ^a   Merlino, C ^a   Segoloni, G P ^b   Giacchino, F ^c   Cavallo, R ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MOLINETTE HOSPITAL   (Italy)

^c Civil Hospital   (Italy)

Author keywords

Autoimmunity; Cytomegalovirus; Kidney transplantation; Non organ specific autoantibodies; Pp65 antigenaemia; Rejection

Indexed keywords

EID: 35048833852     PISSN: 09469648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Paroli M, Schiaffella E, Di Rosa F, Barnaba V (2000) Persisting viruses and autoimmunity. J Neuroimmunol 107: 201-4
2. Ludewig B, Junt T, Hengartner H, Zinkernagel RM (2001) Dendritic cells in autoimmune diseases, Curr Opin Immunol 13: 657-62
3. Ferraro AS, Newkirk MM (1993) Correlative studies of rheumatoid factors and anti-viral antibodies in patients with rheumatoid arthritis. Clin Exp Immunol 92: 425-31
4. Baldwin WM 3rd, Westedt ML, van Gemert GW et al. (1987) Association of rheumatoid factors in renal transplant recipients with cytomegalovirus infection and not with rejection. Transplantation 43: 658-62
5. Mengarelli A, Minotti C, Palumbo G et al. (2000) High levels of antiphospholipid antibodies are associated with cytomegalovirus infection in unre lated bone marrow and cord blood allogeneic stem cell transplantation. Br J Haematol 108: 126-31
6. Labarca JA, Rabaggliati RM, Radrigan FJ et al. (1997) Antiphospholipid syndrome associated with cytomegalovirus infection: case report and review. Clin Infect Dis 24: 197-200
7. Toyoda M, Galfayan K, Galera OA, Petrosian A, Czer LS, Jordan SC (1997) Cytomegalovirus infection induces anti-endothelial cell antibodies in cardiac and renal allograft recipients. Transplant Immunol 5: 104-11
8. Rider JR, Ollier WE, Lock RJ, Brookes ST (1997) Human cytomegalovirus infection and systemic lupus erythematosus. Clin Exp Rheumatol 15: 405-9
9. Fishman JA, Rubin RH (1998) Infection in organtransplant recipients. N Engl J Med 338: 1741-51
10. Sagedal S, Nordal KP, Hartmann A et al. (2000) A prospective study of the natural course of cytomegalovirus infection and disease in renal allograft recipients. Transplantation 70: 1166-74
11. Sagedal S, Hartmann A, Rollag H (2005) The impact of early cytomegalovirus infection and disease in renal transplant recipients. Clin Microbiol Infect 11: 518-30
12. Varani S, Muratori L, De Ruvo N et al. (2002) Autoantibody appearance in cytomegalovirus-infected liver transplant recipients: correlation with antigenemia. J Med Virol 66: 56-62
13. Segoloni GP, Messina M, Squiccimarro G et al. (2005) Preferential allocation of marginal kidney allografts to elderly recipients combined with modified immunosuppression gives good results. Transplantation 80: 953-8
14. Bergallo M, Costa C, Tarallo S et al. (2006) Development of a quantitative-competitive PCR for quantification of human cytomegalovirus load and comparison with antigenaemia, viraemia and pp67 RNA detection by nucleic acid sequence-based amplification. Panminerva Med 48: 119-27
15. Roitt IM, Doniach D (1972) Immunofluorescent test for the detection of antibodies. In: WHO booklet of immunological studies. Geneva: World health Organization; 1
16. Lenzi M, Bellentani S, Saccoccio G et al. (1999) Prevalence of non-organ-specific autoantibodies and chronic liver disease in the general population: a nested case-control study of the Dionysos cohort. Gut 45: 435-41
17. Hebart H, Einsele H, Klein R et al. (1996) CMV infection after allogenic bone marrow transplantation is associated with the occurrence of various autoantibodies and monoclonal gammopathies. Br J Hematol 95: 138-44
18. Yard B, Spruyt-Gerritse M, Claas F et al. (1993) The clinical significance ofallospecific antibodies against endothelial cells detected with an anti-body-dependent cellular cytotoxicity assay for vascular rejection and graft loss after renal transplantation. Transplantation 55: 1287
19. Toyoda M. Petrosian A, Jordan SC (1999) Immunological characterization of antiendothelial cell antibodies induced by cytomegalovirus infection. Transplantation 68: 1311-8
20. Fredrich R, Toyoda M, Czer LS et ai (1999) The clinical significance of antibodies to human vascular endothelial cells after cardiac transplantation. Transplantation 67: 385-91
21. Gerna G, Percivalle E, Baldanti F et al. (2000) Human cytomegalovirus replicates abortively in polymorphonuclear leukocytes after transfer from infected endothelial cells via transient microinfusion events. J Virol 74: 5629-38
22. Dubel L, Farges O, Johanet C, Sebagh M, Bismuth H (1998) High incidence of antitissue antibodies in patients experiencing chronic liver allograft rejection. Transplantation 65: 1072-5
23. Dubel L, Farges O, Sato Y, Bismuth H (1998) Development of antitissue antibodies in the rat liver transplant model. Transplantation 65: 1135-7
24. Dunn MJ, Rose ML, Latif N et al. (1991) Demonstration by Western blotting of antihearth antibodies before and after cardiac transplantation. Transplantation 51: 80612
25. Dunn MJ, Crisp SJ, Rose ML, Taylor PM, Yacoub MH (1992) Antiendothelial antibodies and coronary artery disease after cardiac transplantation. Lancet 339: 156670
26. Rizzetto M, Touscoz G (2001) Autoimmunità per Immagini - Epatogastroenterologia. Torino: Centra Scientifico Editore