Stromal myofibroblasts and malignant transformation in a 4NQO rat tongue carcinogenesis model

Oral Oncology

Volumn 43, Issue 10, 2007, Pages 999-1006

  Vered, Marilena ^a   Allon, Irit ^a   Buchner, Amos ^a   Dayan, Dan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

4NQO; Myofibroblasts; Tongue carcinogenesis

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; ALPHA SMOOTH MUSCLE ACTIN; CYCLINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CARCINOMA IN SITU; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DYSPLASIA; EPITHELIUM CELL; HYPERKERATOSIS; HYPERPLASIA; INVASIVE CARCINOMA; MALE; MALIGNANT TRANSFORMATION; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; STROMA CELL; TONGUE;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; FIBROBLASTS; MALE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; STROMAL CELLS; TONGUE NEOPLASMS;

EID: 34948875726     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2006.11.007     Document Type: Article

References (32)

1. Pisani P., Bray F., and Parkin D.M. Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. Int J Cancer 97 1 (2002) 72-81
2. Lippman S.M., Sudbo J., and Hong W.K. Oral cancer prevention and the evolution of molecular-targeted drug development. J Clin Oncol 23 2 (2005) 346-356
3. Lodi G., Sardella A., Bez C., Demarosi F., and Carrasi A. Interventions for treating oral leukoplakia. Cochrane Database Syst Rev 3 (2004) CD001829
4. Anonymous. Epithelial pathology. In: Neville BW, Damm DD, Allen CA, Bouquot JE, editors. Oral and maxillofacial pathology. China: Saunders, 2002. p. 345.
5. Vered M., Yarom N., and Dayan D. 4NQO oral carcinogenesis: animal models, molecular markers and future expectations. Oral Oncol 41 4 (2005) 337-339
6. Kanojia D., and Vaidya M.M. 4-Nitroquinoline-1-oxide induced experimental oral carcinogenesis. Oral Oncol 42 4 (2006) 655-667
7. Desmouliere A., Guyot C., and Gabbiani G. The stroma reaction myofibroblasts: a key player in the control of tumor behavior. Int J Dev Biol 48 5-6 (2004) 509-517
8. Lewis M.P., Lykoe K.A., Nystrom M.L., Anderson W.P., Speight P.M., Marshall J.F., et al. Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous cell carcinoma cells. Br J Cancer 90 4 (2004) 822-832
9. Barth P.J., Schenck zu Schweinsberq T., Ramaswamy A., and Moll R. CD34+ fibrocytes, alpha-smooth muscle antigen-positive myofibroblasts, and CD117 expression in the stroma of invasive oral squamous cell carcinomas of the oral cavity, pharynx, and larynx. Virchows Arch 444 3 (2004) 231-234
10. Vered M., Shohat I., Buchner A., and Dayan D. Myofibroblasts in stroma of odontogenic cysts and tumors can contribute to variations in the biological behavior of lesions. Oral Oncol 41 10 (2005) 1028-1033
11. Sappino A.P., Skalli O., Jackson B., Schurch W., and Gabbiani G. Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissue. Int J Cancer 41 5 (1988) 707-712
12. Cintorino M., Bellizzi de Marco E., Leoncini P., Tripodi S.A., Xu L.J., Sappino A.P., et al. Expression of alpha-smooth muscle-actin in stromal cells of the uterine cervix during epithelial neoplastic changes. Int J Cancer 47 6 (1991) 843-846
13. Martin M., Pujuguet P., and Martin F. Role of stromal myofibroblasts infiltrating colon cancer in tumor invasion. Pathol Res Pract 192 7 (1996) 712-717
14. Dayan D., Hirshberg A., Kaplan I., Rotem N., and Bodner L. Experimental tongue cancer in desalivated rats. Oral Oncol 33 2 (1997) 105-109
15. Vered M., Daniel N., Hirshberg A., and Dayan D. Histomorphologic and morphometric changes in minor salivary glands of the rat tongue during 4-nitroquinoline-1-oxide-induced carcinogenesis. Oral Oncol 39 5 (2003) 491-496
16. Kaplan I., Engelberg J., and Dayan D. The effect of desalivation on 4-nitroquinoline-1-oxide-induced tongue carcinogenesis: a morphometric study of nucleolar organizer regions. J Oral Pathol Med 30 1 (2001) 48-52
17. Carlile J., Harada K., Baillie R., Macluskey M., Chisholm D.M., Ogden G.R., et al. Vascular endothelial growth factor (VEGF) expression in oral tissues: possible relevance to angiogenesis, tumor progression and field cancerization. J Oral Pathol Med 30 8 (2001) 449-457
18. Macluskey M., Chandrachud L.M., Pazouki S., Green M., Chisholm D.M., Ogden G.R., et al. Apoptosis, proliferation, and angiogenesis in oral tissues. Possible relevance to tumor progression. J Pathol 191 4 (2000) 268-275
19. Bulten J., de Wilde P.C., Schijf C., van der Laak J.A., Wienk S., Poddiqhe P.J., et al. Decreased expression of Ki-67 in atrophic cervical epithelium of post-menopausal women. J Pathol 190 5 (2000) 545-553
20. Maga G., and Hubscher U. Proliferating cell nuclear antigen (PCNA): a dancer with many partners. J Cell Sci 116 Pt 15 (2003) 3051-3060
21. Tsukamoto H., Hayashibe K., Mishima Y., and Ichihashi M. The altered expression of α-smooth muscle actin in basal cell epithelioma and its surrounding stroma: with special reference to proliferating cell nuclear antigen expression and adenoid differentiation. Br J Dermatol 130 2 (1994) 189-194
22. Tomasek J.J., Gabbiani G., Hinz B., Chaponnier C., and Brown R. Myofibroblasts and mechano-regulation of connective tissue remodeling. Nat Rev Mol Cell Biol 3 5 (2002) 349-363
23. De Wever O., and Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 200 4 (2003) 429-447
24. Bucala R., Spiegae L.A., Chesney J., Hogan M., and Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1 1 (1994) 71-81
25. Desmouliere A., Geinoz A., Gabbiani F., and Gabbiani G. Transforming growth factor-β1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultures fibroblasts. J Cell Biol 122 1 (1993) 103-111
26. Ishii G., Sangai T., Oda T., Aoyagi Y., Hasebe T., Kanomata N., et al. Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction. Biochem Biophys Res Commun 309 1 (2003) 232-240
27. Gabbiani G., Csank-Brassert J., Schneeberger J.-C., Kapanci Y., Trenchev P., and Holborow J. Contractile proteins in human cancer cells. Immunofluorescent and electron microscopic study. Am J Pathol 83 3 (1976) 457-474
28. Fan J.-M., Ng Y.-Y., Hill P.A., Nicolik-Paterson D.J., Mu W., Atkins R.C., et al. Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int 56 4 (1999) 1455-1467
29. Yang J., and Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 159 4 (2001) 1465-1475
30. Christian M.M., Moy R.L., Wagner R.F., and Yen-Moore A. A correlation of alpha-smooth muscle actin and invasion in micronodular basal cell carcinoma. Dermatol Surg 27 5 (2001) 441-445
31. Willis B.C., duBois R.M., and Borok Z. Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc 3 4 (2006) 377-382
32. De Vriese A.S., Tilton R.G., Mortier S., and Lamiere N.H. Myofibroblast transdifferentiation of mesothelial is mediated by RAGE and contributes to peritoneal fibrosis in urea. Nephrol Dial Transplant 21 9 (2006) 2549-2555