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1
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33744465649
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Role of allogeneic stem cell transplantation in current treatment of acute myeloid leukemia
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Cornelissen JJ, Lowenberg B. Role of allogeneic stem cell transplantation in current treatment of acute myeloid leukemia. Hematology Am Soc Hematol Educ Program 2005; 151-155.
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(2005)
Hematology Am Soc Hematol Educ Program
, pp. 151-155
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Cornelissen, J.J.1
Lowenberg, B.2
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2
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19944433633
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Conventional versus reduced-intensity conditioning regimen for allogeneic stem cell transplantation in patients with hematological malignancies
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Valcarcel D, Martino R, Sureda A, et al. Conventional versus reduced-intensity conditioning regimen for allogeneic stem cell transplantation in patients with hematological malignancies. Eur J Haematol 2005; 74:144-151.
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(2005)
Eur J Haematol
, vol.74
, pp. 144-151
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Valcarcel, D.1
Martino, R.2
Sureda, A.3
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3
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28644452432
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Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: A retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT)
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Aoudjhane M, Labopin M, Gorin NC, et al. Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT). Leukemia 2005; 19:2304-2312.
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(2005)
Leukemia
, vol.19
, pp. 2304-2312
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Aoudjhane, M.1
Labopin, M.2
Gorin, N.C.3
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4
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3242774628
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Nonablative versus reduced-intensity conditioning regimens in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndrome: Dose is relevant for long-term disease control after allogeneic hematopoietic stem cell transplantation
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De Lima M, Anagnostopoulos A, Munsell M, et al. Nonablative versus reduced-intensity conditioning regimens in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndrome: dose is relevant for long-term disease control after allogeneic hematopoietic stem cell transplantation. Blood 2004; 104:865-872.
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(2004)
Blood
, vol.104
, pp. 865-872
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De Lima, M.1
Anagnostopoulos, A.2
Munsell, M.3
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5
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33746661102
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Martino R, Iacobelli S, Brand R, et al. Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes. Blood 2006; 108:836-846. This large retrospective study from EBMT, showed that 3-year OS and PFS were similar with RIC and SMC; a higher risk of relapse-related death was counterbalanced by a lower NRM in MDS.
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Martino R, Iacobelli S, Brand R, et al. Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes. Blood 2006; 108:836-846. This large retrospective study from EBMT, showed that 3-year OS and PFS were similar with RIC and SMC; a higher risk of relapse-related death was counterbalanced by a lower NRM in MDS.
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6
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34547660729
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Current status of reduced intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia
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This recent review contains in detail all of the current results published referring to RIC in AML and MDS
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Blaise D, Vey N, Faucher C, Mohty M. Current status of reduced intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia. Haematologica 2007; 92:533-541. This recent review contains in detail all of the current results published referring to RIC in AML and MDS.
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(2007)
Haematologica
, vol.92
, pp. 533-541
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Blaise, D.1
Vey, N.2
Faucher, C.3
Mohty, M.4
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7
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33749028534
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Reduced-intensity conditioning for acute myeloid leukemia: Is this strategy correct
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This recent review contains in detail all of the current results published referring to RIC in AML and MDS
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Lazarus HM, Rowe JM. Reduced-intensity conditioning for acute myeloid leukemia: is this strategy correct. Leukemia 2006; 20:1673-1682. This recent review contains in detail all of the current results published referring to RIC in AML and MDS.
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(2006)
Leukemia
, vol.20
, pp. 1673-1682
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Lazarus, H.M.1
Rowe, J.M.2
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8
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33748879386
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Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML
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This recent review contains in detail all of the current results published referring to RIC in AML and MDS
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Niederwieser D, Lange T, Cross M, et al. Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML. Best Pract Res Clin Haematol 2006; 19:825-838. This recent review contains in detail all of the current results published referring to RIC in AML and MDS.
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(2006)
Best Pract Res Clin Haematol
, vol.19
, pp. 825-838
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Niederwieser, D.1
Lange, T.2
Cross, M.3
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10
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34548620532
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Outcomes with myeloid malignancies
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This recent review contains in detail all of the current results published referring to RIC in AML and MDS
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Scott BL, Sandmaier BM. Outcomes with myeloid malignancies. Hematology Am Soc Hematol Educ Program 2006; 381-389. This recent review contains in detail all of the current results published referring to RIC in AML and MDS.
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(2006)
Hematology Am Soc Hematol Educ Program
, pp. 381-389
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Scott, B.L.1
Sandmaier, B.M.2
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11
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33750081766
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Stem cell transplantation with reduced-intensity conditioning regimens: A review of ten years experience with new transplant concepts and new therapeutic agents
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This recent review contains in detail all of the current results published referring to RIC in AML and MDS
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Barrett AJ, Savani BN. Stem cell transplantation with reduced-intensity conditioning regimens: a review of ten years experience with new transplant concepts and new therapeutic agents. Leukemia 2006; 20:1661-1672. This recent review contains in detail all of the current results published referring to RIC in AML and MDS.
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(2006)
Leukemia
, vol.20
, pp. 1661-1672
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Barrett, A.J.1
Savani, B.N.2
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12
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23944440464
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Hematopoietic cell transplantation (HCT)-specific comorbidity index: A new tool for risk assessment before allogeneic HCT
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Sorror ML, Maris MB, Storb R, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood 2005; 106:2912-2919.
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(2005)
Blood
, vol.106
, pp. 2912-2919
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Sorror, M.L.1
Maris, M.B.2
Storb, R.3
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13
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33644967374
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Myeloablative vs nonmyeloablative allogeneic transplantation for patients with myelodysplastic syndrome or acute myelogenous leukemia with multilineage dysplasia: A retrospective analysis
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This single center study compared SMC with RIC in patients with MDS or AML. No differences were founnd in major outcomes suggesting that graft-versusleukemia may be more important that conditioning in preventing relapse
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Scott BL, Sandmaier BM, Storer B, et al. Myeloablative vs nonmyeloablative allogeneic transplantation for patients with myelodysplastic syndrome or acute myelogenous leukemia with multilineage dysplasia: a retrospective analysis. Leukemia 2006; 20:128-135. This single center study compared SMC with RIC in patients with MDS or AML. No differences were founnd in major outcomes suggesting that graft-versusleukemia may be more important that conditioning in preventing relapse.
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(2006)
Leukemia
, vol.20
, pp. 128-135
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Scott, B.L.1
Sandmaier, B.M.2
Storer, B.3
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14
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33644833398
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Treatment for acute myelogenous leukemia by low-dose, total-body, irradiation-based conditioning and hematopoietic cell transplantation from related and unrelated donors
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This multicenter study with a large number of patients showed the results of one of the most common used RIC in patients with AML
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Hegenbart U, Niederwieser D, Sandmaier BM, et al. Treatment for acute myelogenous leukemia by low-dose, total-body, irradiation-based conditioning and hematopoietic cell transplantation from related and unrelated donors. J Clin Oncol 2006; 24:444-453. This multicenter study with a large number of patients showed the results of one of the most common used RIC in patients with AML.
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(2006)
J Clin Oncol
, vol.24
, pp. 444-453
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Hegenbart, U.1
Niederwieser, D.2
Sandmaier, B.M.3
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15
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34948830877
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Fludarabine and busulfan-based reduced intensity conditioning (RIC) allogeneic HLA-identical transplantation (allo-SCT) with or without anti-thymocyte globulin (ATG): Comparison between two prospective studies in patients with myeloid malignancies [abstract]
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Mohty M, Martino R, Faucher C, et al. Fludarabine and busulfan-based reduced intensity conditioning (RIC) allogeneic HLA-identical transplantation (allo-SCT) with or without anti-thymocyte globulin (ATG): Comparison between two prospective studies in patients with myeloid malignancies [abstract]. Blood 2004; 104:1241.
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(2004)
Blood
, vol.104
, pp. 1241
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Mohty, M.1
Martino, R.2
Faucher, C.3
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16
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50149089931
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Reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation with or without alemtuzumab in acute myelogenous leukaemia and myelodysplastic syndromes: Comparison between two prospective studies using fludarabine and oral busulphan [abstract]
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Martino R, Ho A, Sierra J, et al. Reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation with or without alemtuzumab in acute myelogenous leukaemia and myelodysplastic syndromes: Comparison between two prospective studies using fludarabine and oral busulphan [abstract]. Bone Marrow Transplant 2004; 33:O120.
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(2004)
Bone Marrow Transplant
, vol.33
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Martino, R.1
Ho, A.2
Sierra, J.3
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17
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34948904174
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Fludarabine-busulphan reduced intensity conditioning (RIC) Identical sibling allogeneic stem cell transplantation (Allo-SCT) in high-risk acute myeloid leukemia and myelodisplastic syndrome [abstract]
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Valcárcel D, Martino R, Martin J. Fludarabine-busulphan reduced intensity conditioning (RIC) Identical sibling allogeneic stem cell transplantation (Allo-SCT) in high-risk acute myeloid leukemia and myelodisplastic syndrome [abstract]. Biol Blood Marrow Transplant 2007; 13:134-135.
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(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 134-135
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Valcárcel, D.1
Martino, R.2
Martin, J.3
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18
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27244434510
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Reduced intensity conditioning prior to allogeneic stem cell transplantation for patients with acute myeloblastic leukemia as a first-line treatment
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Blaise DP, Michel BJ, Faucher C, et al. Reduced intensity conditioning prior to allogeneic stem cell transplantation for patients with acute myeloblastic leukemia as a first-line treatment. Cancer 2005; 104:1931-1938.
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(2005)
Cancer
, vol.104
, pp. 1931-1938
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Blaise, D.P.1
Michel, B.J.2
Faucher, C.3
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19
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0037105538
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Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes
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Martino R, Caballero MD, Simon JA, et al. Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes. Blood 2002; 100:2243-2245.
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(2002)
Blood
, vol.100
, pp. 2243-2245
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Martino, R.1
Caballero, M.D.2
Simon, J.A.3
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20
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24944582579
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Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome
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Van Besien K, Artz A, Smith S, et al. Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome. J Clin Oncol 2005; 23:5728-5738.
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(2005)
J Clin Oncol
, vol.23
, pp. 5728-5738
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Van Besien, K.1
Artz, A.2
Smith, S.3
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21
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33644820764
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Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia
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Tauro S, Craddock C, Peggs K, et al. Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia. J Clin Oncol 2005; 23: 9387-9393.
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(2005)
J Clin Oncol
, vol.23
, pp. 9387-9393
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Tauro, S.1
Craddock, C.2
Peggs, K.3
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22
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2442662929
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Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies
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Hamaki T, Kami M, Kim SW, et al. Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies. Bone Marrow Transplant 2004; 33:891-900.
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(2004)
Bone Marrow Transplant
, vol.33
, pp. 891-900
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Hamaki, T.1
Kami, M.2
Kim, S.W.3
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23
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33646491445
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Reduced intensity conditioning allows for up-front allogeneic hematopoietic stem cell transplantation after cytoreductive induction therapy in newly-diagnosed high-risk acute myeloid leukemia
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This single center trial showed that up-front allogeneic-HSCT with RIC after induction therapy, in newly diagnosed high risk patients seems effective
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Platzbecker U, Thiede C, Fussel M, et al. Reduced intensity conditioning allows for up-front allogeneic hematopoietic stem cell transplantation after cytoreductive induction therapy in newly-diagnosed high-risk acute myeloid leukemia. Leukemia 2006; 20:707-714. This single center trial showed that up-front allogeneic-HSCT with RIC after induction therapy, in newly diagnosed high risk patients seems effective.
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(2006)
Leukemia
, vol.20
, pp. 707-714
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Platzbecker, U.1
Thiede, C.2
Fussel, M.3
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24
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33947255173
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Allogeneic hematopoietic stem cell transplantation for the treatment of high-risk acute myelogenous leukemia and myelodysplastic syndrome using reduced-intensity conditioning with fludarabine and melphalan
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This single center study showed the results of Flu-Melphalan RIC regimen in patients with AML/MDS with related and unrelated donors
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Oran B, Giralt S, Saliba R, et al. Allogeneic hematopoietic stem cell transplantation for the treatment of high-risk acute myelogenous leukemia and myelodysplastic syndrome using reduced-intensity conditioning with fludarabine and melphalan. Biol Blood Marrow Transplant 2007; 13:454-462. This single center study showed the results of Flu-Melphalan RIC regimen in patients with AML/MDS with related and unrelated donors.
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(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 454-462
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Oran, B.1
Giralt, S.2
Saliba, R.3
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25
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34247142077
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Grigg AP, Gibson J, Bardy et al. A prospective multicenter trial of peripheral blood stem cell sibling allografts for acute myeloid leukemia in first complete remission using fludarabine-cyclophosphamide reduced intensity conditioning. Biol Blood Marrow Transplant 2007; 13:560-567. This multicenter prospective study showed the results of fludarabine-cyclophosphamide RIC regimen in patients with high risk AML in first line.
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Grigg AP, Gibson J, Bardy PG, et al. A prospective multicenter trial of peripheral blood stem cell sibling allografts for acute myeloid leukemia in first complete remission using fludarabine-cyclophosphamide reduced intensity conditioning. Biol Blood Marrow Transplant 2007; 13:560-567. This multicenter prospective study showed the results of fludarabine-cyclophosphamide RIC regimen in patients with high risk AML in first line.
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26
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24944495973
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Sequential regimen of chemotherapy, reduced-intensity conditioning for allogeneic stem-cell transplantation, and prophylactic donor lymphocyte transfusion in high-risk acute myeloid leukemia and myelodysplastic syndrome
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Schmid C, Schleuning M, Ledderose G, et al. Sequential regimen of chemotherapy, reduced-intensity conditioning for allogeneic stem-cell transplantation, and prophylactic donor lymphocyte transfusion in high-risk acute myeloid leukemia and myelodysplastic syndrome. J Clin Oncol 2005; 23: 5675-5687.
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(2005)
J Clin Oncol
, vol.23
, pp. 5675-5687
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Schmid, C.1
Schleuning, M.2
Ledderose, G.3
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27
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33746607667
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Schmid C, Schleuning M, Schwerdtfeger R, et al. Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation. Blood 2006; 108:1092-1099. This prospective study suggested that performing an RIC a few days after salvage Flu-HD ARA-C containing salvage chemotherapy may be feasible and reduces the risk of early relapse in high risk or refractory AML/MDS.
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Schmid C, Schleuning M, Schwerdtfeger R, et al. Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation. Blood 2006; 108:1092-1099. This prospective study suggested that performing an RIC a few days after salvage Flu-HD ARA-C containing salvage chemotherapy may be feasible and reduces the risk of early relapse in high risk or refractory AML/MDS.
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28
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34248343441
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Results of a phase I/II study of gemtuzumab ozogamicin added to fludarabine (F), melphalan (M) and allogeneic hematopoietic stem cell transplantation (HSCT) for relapsed myeloid leukemias [abstract]
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Lima de M, Giralt S, Caldera G, et al. Results of a phase I/II study of gemtuzumab ozogamicin added to fludarabine (F), melphalan (M) and allogeneic hematopoietic stem cell transplantation (HSCT) for relapsed myeloid leukemias [abstract]. Blood 2005; 106:841.
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(2005)
Blood
, vol.106
, pp. 841
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Lima de, M.1
Giralt, S.2
Caldera, G.3
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29
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34948895397
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Maintenance therapy with 5-azacitidina (5-AC) after allogeneic stem cell transplantation (Allo-SCT) for acute myelogenous leukemia (AML) and high risk myelodisplastic syndrome (MDS): A dose and schedule finding study [abstract]
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Soriano Andres O, Champlin RE, McCormic G, et al. Maintenance therapy with 5-azacitidina (5-AC) after allogeneic stem cell transplantation (Allo-SCT) for acute myelogenous leukemia (AML) and high risk myelodisplastic syndrome (MDS): a dose and schedule finding study [abstract]. Blood 2007; 108:3668.
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(2007)
Blood
, vol.108
, pp. 3668
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Soriano Andres, O.1
Champlin, R.E.2
McCormic, G.3
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30
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50149121496
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Reduced intensity conditioning allogeneic stem cell transplantation followed by targeted condolidation immunotherapy with gemtuzubam ozogamicin in children and adolescents with CD33+ acute myeloid leukemia [abstract]
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Roman E, Cooney E, Militano O, et al. Reduced intensity conditioning allogeneic stem cell transplantation followed by targeted condolidation immunotherapy with gemtuzubam ozogamicin in children and adolescents with CD33+ acute myeloid leukemia [abstract]. Biol Blood Marrow Transplant 2007; 13:76.
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(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 76
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Roman, E.1
Cooney, E.2
Militano, O.3
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31
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9144234680
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Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning
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Bethge A, Hegenbart U, Stuart M, et al. Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning. Blood 2004; 103:790-795.
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(2004)
Blood
, vol.103
, pp. 790-795
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Bethge, A.1
Hegenbart, U.2
Stuart, M.3
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32
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0036839595
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The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation
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Marks DI, Lush R, Cavenagh J, et al. The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation. Blood 2002; 100:3108-3114.
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(2002)
Blood
, vol.100
, pp. 3108-3114
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Marks, D.I.1
Lush, R.2
Cavenagh, J.3
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33
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33846003456
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Prophylactic transfer of CD8-depleted donor lymphocytes after T-cell-depleted reduced-intensity transplantation
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Meyer R, Britten C, Wehler D, et al. Prophylactic transfer of CD8-depleted donor lymphocytes after T-cell-depleted reduced-intensity transplantation. Blood 2007; 109:374-382.
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(2007)
Blood
, vol.109
, pp. 374-382
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Meyer, R.1
Britten, C.2
Wehler, D.3
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