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34948817962
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Electrolyses carried out at a lower temperature (-20°C) led to lower chemical yields in β-lactams, with no improvement in the dr.
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Electrolyses carried out at a lower temperature (-20°C) led to lower chemical yields in β-lactams, with no improvement in the dr.
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20
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34948907617
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An increase in the number of Faradays per mol had no effect, see ref.[1
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[1]
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21
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4544371091
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23
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34948814854
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The low yield in cis-β-lactam 2f can be due both to the high steric hindrance of this chiral auxiliary and to the fact that under these experimental conditions part of the auxiliary is removed (either from starting amide 1f or from product 2f). In fact, from the cathodic solution Oppolzer's camphor sultam has been isolated.
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The low yield in cis-β-lactam 2f can be due both to the high steric hindrance of this chiral auxiliary and to the fact that under these experimental conditions part of the auxiliary is removed (either from starting amide 1f or from product 2f). In fact, from the cathodic solution Oppolzer's camphor sultam has been isolated.
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24
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0024405003
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N. Miyachi, F. Kanda, M. Shibasaki, J. Org. Chem. 1989, 54, 3511-3513.
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