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Volumn 10, Issue 3, 2007, Pages 311-318

Multiple oral dosing of ketoconazole increases dog exposure to ivermectin

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLYCOPROTEIN P; IVERMECTIN; KETOCONAZOLE; KETOFUNGOL; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; ANTIPARASITIC AGENT;

EID: 34848924630     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (45)

References (50)
  • 3
    • 0142258167 scopus 로고    scopus 로고
    • Mass drug treatment for lymphatic filariasis and onchocerciasis
    • Molyneux, D. H., Bradley, M., Hoerauf, A., Kyelem, D. and Taylor, M. J., Mass drug treatment for lymphatic filariasis and onchocerciasis. Trends Parasitol, 19(11): 516-22, 2003.
    • (2003) Trends Parasitol , vol.19 , Issue.11 , pp. 516-522
    • Molyneux, D.H.1    Bradley, M.2    Hoerauf, A.3    Kyelem, D.4    Taylor, M.J.5
  • 4
    • 0036434186 scopus 로고    scopus 로고
    • Ivermectin-responsive Demodex infestation during human immunodeficiency virus infection. A case report and literature review
    • Aquilina, C., Viraben, R. and Sire, S., Ivermectin-responsive Demodex infestation during human immunodeficiency virus infection. A case report and literature review. Dermatology, 205(4): 394-7, 2002.
    • (2002) Dermatology , vol.205 , Issue.4 , pp. 394-397
    • Aquilina, C.1    Viraben, R.2    Sire, S.3
  • 5
    • 30044439664 scopus 로고    scopus 로고
    • Ivermectin: Pharmacology and application in dermatology
    • Dourmishev, A. L., Dourmishev, L. A. and Schwartz, R. A., Ivermectin: pharmacology and application in dermatology. Int J Dermatol, 44(12): 981-8, 2005.
    • (2005) Int J Dermatol , vol.44 , Issue.12 , pp. 981-988
    • Dourmishev, A.L.1    Dourmishev, L.A.2    Schwartz, R.A.3
  • 7
    • 0031060625 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein-associated multidrug resistance by ivermectin
    • Pouliot, J. F., L'Heureux, F., Liu, Z., Prichard, R. K. and Georges, E., Reversal of P-glycoprotein-associated multidrug resistance by ivermectin. Biochem Pharmacol, 53(1): 17-25, 1997.
    • (1997) Biochem Pharmacol , vol.53 , Issue.1 , pp. 17-25
    • Pouliot, J.F.1    L'Heureux, F.2    Liu, Z.3    Prichard, R.K.4    Georges, E.5
  • 9
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • Schinkel, A. H. and Jonker, J. W., Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev, 55(1): 3-29, 2003.
    • (2003) Adv Drug Deliv Rev , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 10
    • 8344244484 scopus 로고    scopus 로고
    • Therapeutic implications of the MDR-1 gene
    • Mealey, K. L., Therapeutic implications of the MDR-1 gene. J Vet Pharmacol Ther, 27(5): 257-64, 2004.
    • (2004) J Vet Pharmacol Ther , vol.27 , Issue.5 , pp. 257-264
    • Mealey, K.L.1
  • 12
    • 0242523974 scopus 로고    scopus 로고
    • Mealey, K. L., Northrup, N. C. and Bentjen, S. A., Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity. J Am Vet Med Assoc, 223(10): 1453-5, 1434, 2003.
    • Mealey, K. L., Northrup, N. C. and Bentjen, S. A., Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity. J Am Vet Med Assoc, 223(10): 1453-5, 1434, 2003.
  • 13
    • 0035164622 scopus 로고    scopus 로고
    • Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene
    • Mealey, K. L., Bentjen, S. A., Gay, J. M. and Cantor, G. H., Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene. Pharmacogenetics, 11(8): 727-33, 2001.
    • (2001) Pharmacogenetics , vol.11 , Issue.8 , pp. 727-733
    • Mealey, K.L.1    Bentjen, S.A.2    Gay, J.M.3    Cantor, G.H.4
  • 14
    • 0037462462 scopus 로고    scopus 로고
    • MDR1-deficient genotype in Collie dogs hypersensitive to the P-glycoprotein substrate ivermectin
    • Roulet, A., Puel, O., Gesta, S., Lepage, J. F., Drag, M., Soll, M., Alvinerie, M. and Pineau, T., MDR1-deficient genotype in Collie dogs hypersensitive to the P-glycoprotein substrate ivermectin. Eur J Pharmacol, 460(2-3): 85-91, 2003.
    • (2003) Eur J Pharmacol , vol.460 , Issue.2-3 , pp. 85-91
    • Roulet, A.1    Puel, O.2    Gesta, S.3    Lepage, J.F.4    Drag, M.5    Soll, M.6    Alvinerie, M.7    Pineau, T.8
  • 16
    • 4243050943 scopus 로고    scopus 로고
    • Ivermectin: Does P-glycoprotein play a role in neurotoxicity?
    • Edwards, G., Ivermectin: does P-glycoprotein play a role in neurotoxicity? Filaria J, 2 Suppl 1: S8, 2003.
    • (2003) Filaria J , vol.2 , Issue.SUPPL. 1
    • Edwards, G.1
  • 17
    • 35848964299 scopus 로고    scopus 로고
    • Mackenzie, C. D., Geary, T. G. and Gerlach, J. A., Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients. Filaria J, 2 SuppI 1: S5, 2003.
    • Mackenzie, C. D., Geary, T. G. and Gerlach, J. A., Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients. Filaria J, 2 SuppI 1: S5, 2003.
  • 18
    • 0042759615 scopus 로고    scopus 로고
    • Serious adverse events following treatment with ivermectin for onchocerciasis control: A review of reported cases
    • Twum-Danso, N. A., Serious adverse events following treatment with ivermectin for onchocerciasis control: a review of reported cases. Filaria J, 2 Suppl 1: S3, 2003.
    • (2003) Filaria J , vol.2 , Issue.SUPPL. 1
    • Twum-Danso, N.A.1
  • 19
    • 0023354522 scopus 로고
    • Use of ketoconazole in treatment of dermatophytosis in a dog
    • Angarano, D. W. and Scott, D. W., Use of ketoconazole in treatment of dermatophytosis in a dog. J Am Vet Med Assoc, 190(11): 1433-4, 1987.
    • (1987) J Am Vet Med Assoc , vol.190 , Issue.11 , pp. 1433-1434
    • Angarano, D.W.1    Scott, D.W.2
  • 20
    • 0021255150 scopus 로고
    • Treatment of canine blastomycosis with amphotericin B and ketoconazole
    • Legendre, A. M., Selcer, B. A., Edwards, D. F. and Stevens, R., Treatment of canine blastomycosis with amphotericin B and ketoconazole. J Am Vet Med Assoc, 184(10): 1249-54, 1984.
    • (1984) J Am Vet Med Assoc , vol.184 , Issue.10 , pp. 1249-1254
    • Legendre, A.M.1    Selcer, B.A.2    Edwards, D.F.3    Stevens, R.4
  • 21
    • 0024508662 scopus 로고
    • Use of ketoconazole in the treatment of canine nasal aspergillosis
    • Sharp, N. J: and Sullivan, M., Use of ketoconazole in the treatment of canine nasal aspergillosis. J Am Vet Med Assoc, 194(6): 782-6, 1989.
    • (1989) J Am Vet Med Assoc , vol.194 , Issue.6 , pp. 782-786
    • Sharp, N.J.1    Sullivan, M.2
  • 22
    • 0024357722 scopus 로고
    • Ketoconazole therapy in a dog with systemic cryptococcosis
    • Mason, G. D., Labato, M. A. and Bachrach, A., Jr., Ketoconazole therapy in a dog with systemic cryptococcosis. J Am Vet Med Assoc, 195(7): 954-6, 1989.
    • (1989) J Am Vet Med Assoc , vol.195 , Issue.7 , pp. 954-956
    • Mason, G.D.1    Labato, M.A.2    Bachrach Jr., A.3
  • 23
    • 0025082894 scopus 로고
    • Plasma cortisol response to ketoconazole administration in dogs with hyperadrenocorticism
    • Feldman, E. C., Bruyette, D. S., Nelson, R. W. and Farver, T. B., Plasma cortisol response to ketoconazole administration in dogs with hyperadrenocorticism. J Am Vet Med Assoc, 197(1): 71-8, 1990.
    • (1990) J Am Vet Med Assoc , vol.197 , Issue.1 , pp. 71-78
    • Feldman, E.C.1    Bruyette, D.S.2    Nelson, R.W.3    Farver, T.B.4
  • 24
    • 0030430033 scopus 로고    scopus 로고
    • Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes
    • Bourrie, M., Meunier, V., Berger, Y. and Fabre, G., Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes. J Pharmacol Exp Ther, 277(1): 321-32, 1996.
    • (1996) J Pharmacol Exp Ther , vol.277 , Issue.1 , pp. 321-332
    • Bourrie, M.1    Meunier, V.2    Berger, Y.3    Fabre, G.4
  • 25
    • 0026595179 scopus 로고
    • Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture
    • Maurice, M., Pichard, L., Daujat, M., Fabre, I., Joyeux, H., Domergue, J. and Maurel, P., Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture. Faseb J, 6(2): 752-8, 1992.
    • (1992) Faseb J , vol.6 , Issue.2 , pp. 752-758
    • Maurice, M.1    Pichard, L.2    Daujat, M.3    Fabre, I.4    Joyeux, H.5    Domergue, J.6    Maurel, P.7
  • 26
    • 0029123393 scopus 로고
    • The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine
    • Gomez, D. Y., Wacher, V. J., Tomlanovich, S. J., Hebert, M. F. and Benet, L. Z., The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine. Clin Pharmacol Ther, 58(1): 15-9, 1995.
    • (1995) Clin Pharmacol Ther , vol.58 , Issue.1 , pp. 15-19
    • Gomez, D.Y.1    Wacher, V.J.2    Tomlanovich, S.J.3    Hebert, M.F.4    Benet, L.Z.5
  • 28
    • 0036017314 scopus 로고    scopus 로고
    • In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes
    • Kuroha, M., Kuze, Y., Shimoda, M. and Kokue, E., In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes. Am J Yet Res, 63(6): 900-5, 2002.
    • (2002) Am J Yet Res , vol.63 , Issue.6 , pp. 900-905
    • Kuroha, M.1    Kuze, Y.2    Shimoda, M.3    Kokue, E.4
  • 29
    • 0036135722 scopus 로고    scopus 로고
    • Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs
    • Kuroha, M., Azumano, A., Kuze, Y., Shimoda, M. and Kokue, E., Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs. Drug Metab Dispos, 30(1): 63-8, 2002.
    • (2002) Drug Metab Dispos , vol.30 , Issue.1 , pp. 63-68
    • Kuroha, M.1    Azumano, A.2    Kuze, Y.3    Shimoda, M.4    Kokue, E.5
  • 30
    • 0036281241 scopus 로고    scopus 로고
    • Effect of oral ketoconazole on first-pass effect of nifedipine after oral administration in dogs
    • Kuroha, M., Kayaba, H., Kishimoto, S., Khalil, W. F., Shimoda, M. and Kokue, E., Effect of oral ketoconazole on first-pass effect of nifedipine after oral administration in dogs. J Pharm Sci, 91(3): 868-73, 2002.
    • (2002) J Pharm Sci , vol.91 , Issue.3 , pp. 868-873
    • Kuroha, M.1    Kayaba, H.2    Kishimoto, S.3    Khalil, W.F.4    Shimoda, M.5    Kokue, E.6
  • 31
    • 0842347428 scopus 로고    scopus 로고
    • Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey
    • Ward, K. W., Stelman, G. J., Morgan, J. A., Zeigler, K. S., Azzarano, L. M., Kehler, J. R., McSurdy-Freed, J. E., Proksch, J. W. and Smith, B. R., Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey. Drug Metab Dispos, 32(2): 172-7, 2004.
    • (2004) Drug Metab Dispos , vol.32 , Issue.2 , pp. 172-177
    • Ward, K.W.1    Stelman, G.J.2    Morgan, J.A.3    Zeigler, K.S.4    Azzarano, L.M.5    Kehler, J.R.6    McSurdy-Freed, J.E.7    Proksch, J.W.8    Smith, B.R.9
  • 32
    • 0033992329 scopus 로고    scopus 로고
    • Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle
    • Lifschitz, A., Virkel, G., Sallovitz, J., Sutra, J. F., Galtier, P., Alvinerie, M. and Lanusse, C., Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle. Vet Parasitol, 87(4): 327-38, 2000.
    • (2000) Vet Parasitol , vol.87 , Issue.4 , pp. 327-338
    • Lifschitz, A.1    Virkel, G.2    Sallovitz, J.3    Sutra, J.F.4    Galtier, P.5    Alvinerie, M.6    Lanusse, C.7
  • 34
    • 0019974468 scopus 로고
    • Noncompartmental determination of the steady-state volume of distribution for any mode of administration
    • Perrier, D. and Mayersohn, M., Noncompartmental determination of the steady-state volume of distribution for any mode of administration. J Pharm Sci, 71(3): 372-3, 1982.
    • (1982) J Pharm Sci , vol.71 , Issue.3 , pp. 372-373
    • Perrier, D.1    Mayersohn, M.2
  • 35
    • 30944435617 scopus 로고    scopus 로고
    • Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs
    • Gokbulut, C., Karademir, U., Boyacioglu, M. and McKellar, Q. A., Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs. Vet Parasitol, 135(3-4): 347-54, 2006.
    • (2006) Vet Parasitol , vol.135 , Issue.3-4 , pp. 347-354
    • Gokbulut, C.1    Karademir, U.2    Boyacioglu, M.3    McKellar, Q.A.4
  • 37
    • 0023550895 scopus 로고
    • Comparative in vivo and in vitro metabolism of ivermectin in steers, sheep, swine, and rat
    • Chiu, S. H., Taub, R., Sestokas, E., Lu, A. Y. and Jacob, T. A., Comparative in vivo and in vitro metabolism of ivermectin in steers, sheep, swine, and rat. Drug Metab Rev, 18(2-3): 289-302, 1987.
    • (1987) Drug Metab Rev , vol.18 , Issue.2-3 , pp. 289-302
    • Chiu, S.H.1    Taub, R.2    Sestokas, E.3    Lu, A.Y.4    Jacob, T.A.5
  • 38
    • 8344226085 scopus 로고    scopus 로고
    • Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs
    • Kuroha, M., Shirai, Y. and Shimoda, M., Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs. J Vet Pharmacol Ther, 27(5): 355-9, 2004.
    • (2004) J Vet Pharmacol Ther , vol.27 , Issue.5 , pp. 355-359
    • Kuroha, M.1    Shirai, Y.2    Shimoda, M.3
  • 39
    • 23844442993 scopus 로고    scopus 로고
    • Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers
    • Ridtitid, W., Wongnawa, M., Mahatthanatrakul, W., Raungsri, N. and Sunbhanich, M., Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers. J Clin Pharm Ther, 30(3): 285-90, 2005.
    • (2005) J Clin Pharm Ther , vol.30 , Issue.3 , pp. 285-290
    • Ridtitid, W.1    Wongnawa, M.2    Mahatthanatrakul, W.3    Raungsri, N.4    Sunbhanich, M.5
  • 40
    • 34548608515 scopus 로고    scopus 로고
    • Effect of Oral Ketoconazole on Intestinal First-pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys
    • in press
    • Ogasawara, A., Kume, T. and Kazama, E., Effect of Oral Ketoconazole on Intestinal First-pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys. Drug Metab Dispos, (in press). 2006.
    • (2006) Drug Metab Dispos
    • Ogasawara, A.1    Kume, T.2    Kazama, E.3
  • 41
    • 33644898140 scopus 로고    scopus 로고
    • Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics
    • Grimm, S. W., Richtand, N. M., Winter, H. R., Stams, K. R. and Reele, S. B., Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. Br J Clin Pharmacol, 61(1): 58-69, 2006.
    • (2006) Br J Clin Pharmacol , vol.61 , Issue.1 , pp. 58-69
    • Grimm, S.W.1    Richtand, N.M.2    Winter, H.R.3    Stams, K.R.4    Reele, S.B.5
  • 43
    • 33344474213 scopus 로고    scopus 로고
    • Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: In vitro and in vivo assessments
    • Ballent, M., Lifschitz, A., Virkel, G., Sallovitz, J. and Lanusse, C., Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: in vitro and in vivo assessments. Drug Metab Dispos, 34(3): 457-63, 2006.
    • (2006) Drug Metab Dispos , vol.34 , Issue.3 , pp. 457-463
    • Ballent, M.1    Lifschitz, A.2    Virkel, G.3    Sallovitz, J.4    Lanusse, C.5
  • 44
    • 0036263229 scopus 로고    scopus 로고
    • Intestinal secretion is a major route for parent ivermectin elimination in the rat
    • Laffont, C. M., Toutain, P. L., Alvinerie, M. and Bousquet-Melou, A., Intestinal secretion is a major route for parent ivermectin elimination in the rat. Drug Metab Dispos, 30(6): 626-30, 2002.
    • (2002) Drug Metab Dispos , vol.30 , Issue.6 , pp. 626-630
    • Laffont, C.M.1    Toutain, P.L.2    Alvinerie, M.3    Bousquet-Melou, A.4
  • 45
    • 0032860581 scopus 로고    scopus 로고
    • Enhanced absorption of pour-on ivermectin formulation in rats by co-administration of the multidrug-resistant-reversing agent verapamil
    • Alvinerie, M., Dupuy, J., Eeckhoutte, C. and Sutra, J. F., Enhanced absorption of pour-on ivermectin formulation in rats by co-administration of the multidrug-resistant-reversing agent verapamil. Parasitol Res, 85(11): 920-2, 1999.
    • (1999) Parasitol Res , vol.85 , Issue.11 , pp. 920-922
    • Alvinerie, M.1    Dupuy, J.2    Eeckhoutte, C.3    Sutra, J.F.4
  • 46
    • 0442298029 scopus 로고    scopus 로고
    • Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep
    • Molento, M. B., Lifschitz, A., Sallovitz, J., Lanusse, C. and Prichard, R., Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep. Parasitol Res, 92(2): 121-7, 2004.
    • (2004) Parasitol Res , vol.92 , Issue.2 , pp. 121-127
    • Molento, M.B.1    Lifschitz, A.2    Sallovitz, J.3    Lanusse, C.4    Prichard, R.5
  • 48
    • 19444367783 scopus 로고    scopus 로고
    • In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats
    • Kageyama, M., Namiki, H., Fukushima, H., Ito, Y., Shibata, N. and Takada, K., In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats. Biol Pharm Bull, 28(2): 316-22, 2005.
    • (2005) Biol Pharm Bull , vol.28 , Issue.2 , pp. 316-322
    • Kageyama, M.1    Namiki, H.2    Fukushima, H.3    Ito, Y.4    Shibata, N.5    Takada, K.6
  • 49
    • 0038207541 scopus 로고    scopus 로고
    • Genetic polymorphisms of the human MDR1 drug transporter
    • Schwab, M., Eichelbaum, A and Fromm, M. F., Genetic polymorphisms of the human MDR1 drug transporter. Annu Rev Pharmacol Toxicol, 43: 285-307, 2003.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 285-307
    • Schwab, M.1    Eichelbaum, A.2    Fromm, M.F.3
  • 50
    • 12344334846 scopus 로고    scopus 로고
    • Clinical aspects of the MDR1 (ABCB1) gene polymorphism
    • Eichelbaum, M., Fromm, M. F. and Schwab, M., Clinical aspects of the MDR1 (ABCB1) gene polymorphism. Ther Drug Monit, 26(2): 180-5, 2004.
    • (2004) Ther Drug Monit , vol.26 , Issue.2 , pp. 180-185
    • Eichelbaum, M.1    Fromm, M.F.2    Schwab, M.3


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