Protective effects of erdosteine and vitamins C and E combination on ischemia-reperfusion-induced lung oxidative stress and plasma copper and zinc levels in a rat hind limb model

Biological Trace Element Research

Volumn 118, Issue 1, 2007, Pages 43-52

  Sirmali, Mehmet ^a   Uz, Efkan ^a   Sirmali, Rana ^a   Kilbaş, Aynur ^a   Yilmaz, H Ramazan ^a   Altuntaş, Irfan ^a   Naziroǧlu, Mustafa ^b   Delibaş, Namik ^a   Vural, Hüseyin ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY   (Turkey)

Author keywords

Antioxidant vitamins; Erdosteine; Ischemia reperfusion; Lung; Zinc

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CARBONIC ACID; CATALASE; COPPER; CREATINE KINASE; ERDOSTEINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PLACEBO; SUPEROXIDE DISMUTASE; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARBON DIOXIDE TENSION; COMPARATIVE STUDY; CONTROLLED STUDY; COPPER BLOOD LEVEL; CREATININE BLOOD LEVEL; DISEASE MODEL; DRUG EFFECT; ENZYME ACTIVITY; HINDLIMB; ISCHEMIA; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LUNG INJURY; LUNG PARENCHYMA; MALE; NONHUMAN; OXIDATIVE STRESS; OXYGEN TENSION; PH; PROTECTION; RAT; REPERFUSION; ZINC BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; COPPER; CREATINE KINASE; EXPECTORANTS; GLUTATHIONE; L-LACTATE DEHYDROGENASE; LOWER EXTREMITY; LUNG; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; THIOGLYCOLATES; THIOPHENES; VITAMIN E; ZINC;

ANIMALIA; RATTUS;

EID: 34848921529     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12011-007-0010-3     Document Type: Article

References (37)

1. Welbourn CRB, Goldman G, Peterson IS (1991) Pathophysiology of ischemia-reperfusion injury: central role of the neutrophil. Br J Surg 78:651-655
2. Calikoglu M, Tamer L, Sucu N et al (2003) The effects of caffeic acid phenethyl ester on tissue damage in lung after hindlimb ischemia-reperfusion. Pharmacol Res 48:397-403
3. Carden DL, Granger DN (2000) Pathophysiology of ischemia-reperfusion injury. J Pathol 190:255-266
4. Sucu N, Unlu A, Tamer L et al (2002) Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion. Pharmacol Res 46:345-349
5. Seekamp A, Ward PA (1993) Ischemia-reperfusion injury. Agents Actions 41(Suppl):137-152
6. Cuzzocrea S, Riley DP, Caputi AP et al (2001) Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 53:135-159
7. van der Vliet A, Cross CE (2000) Oxidants, nitrosants, and the lung. Am J Med 109:398-421
8. Ince H, Kandemir E, Bagci C et al (2006) The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia. Med Sci Monit 12:187-183
9. Ege E, Ilhan A, Gurel A et al (2004) Erdosteine ameliorates neurological outcome and oxidative stress due to ischemia/reperfusion injury in rabbit spinal cord. Eur J Vasc Endovasc Surg 28:379-386
10. Demiralay R, Gursan N, Ozbilim G et al (2006) Comparison of the effects of erdosteine and N-acetylcysteine on apoptosis regulation in endotoxin-induced acute lung injury. J Appl Toxicol 26:301-308
11. Braga PC, Dal Sasso M, Zuccotti T (2000) Assessment of the antioxidant activity of the SH metabolite I of erdosteine on human neutrophil oxidative bursts. Arzneimittelforschung 50:739-746
12. Altuntas I, Delibas N, Demirci M, Kilinc I, Tamer N (2002) The effects of methidathion on lipid peroxidation and some liver enzymes: role of vitamins E and C. Arch Toxicol 76:470-473
13. Naziroǧlu M, Şimşek M, Kutlu M (2004) Moderate exercise with dietary vitamin C and E combination protects streptozotocin- induced oxidative damage to the blood and improves fetal outcomes in pregnant rats. Clin Chem Lab Med 42:511-517
14. Aydemir O, Naziroǧlu M, Çelebi S, Yilmaz T, Kükner AS (2004) Antioxidant effects of alpha, gamma- and succinate-tocopherols in guinea pig retina during ischemia-reperfusion injury. Pathophysiology 11:167-171
15. Whanger PD (2001) Selenium and the brain: a review. Nutr Neurosci 4:81-97
16. Akcil E, Tug T, Doseyen Z (2000) Antioxidant enzyme activities and trace element concentrations in ischemia-reperfusion. Biol Trace Elem Res 76:13-17
17. Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 186:421-431
18. Woolliams JA, Wiener G, Anderson PH et al (1983) Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood various breed crosses of sheep. Res Vet Sci 34:69-77
19. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
20. Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158-169
21. Beutler E, Duron O, Kelly BM (1963) Improved method for the determination of blood glutathione. J Lab Clin Med 61:882-883
22. Lowry OH, Rosebrough NJ, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 182:265-268
23. Kim JD, Baker CJ, Roberts RF et al (2000) Platelet activating factor acetylhydrolase decreases lung reperfusion injury. Ann Thorac Surg 70:423-428
24. Paterson IS, Klausner JM, Pugatch R et al (1989) Noncardiogenic pulmonary edema after abdominal aortic aneurysm surgery. Ann Surg 209:231-236
25. Simpson R, Alon R, Kobzik L et al (1993) Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. Ann Surg 218:444-453
26. Abdih H, Kelly CJ, Bouchier-Hayes D et al (1994) Nitric oxide (endothelium-derived relaxaing factor) attenuates revascularization-induced lung injury. J Surg Res 57:39-43
27. Dal Sasso M, Culici M, Guffanti EE, Bianchi T, Fonti E, Braga PC (2005) A combination of budesonide and the SH-metabolite I of erdosteine acts synergistically in reducing chemiluminescence during human neutrophil respiratory burst. Pharmacology 74:127-134
28. Stallone RJ, Lim RC, Blaisdell FW (1969) Pathogenesis of the pulmonary changes following ischemia of the lower extremities. Ann Thorac Surg 7:539-549
29. Gurel A, Armutcu F, Cihan A et al (2004) Erdosteine improves oxidative damage in a rat model of renal ischemia-reperfusion injury. Eur Surg Res 36:206-209
30. Koksel O, Ozdulger A, Aytacoglu B et al (2005) The influence of iloprost on acute lung injury induced by hind limb ischemia-reperfusion in rats. Pulm Pharmacol Ther 18:235-241
31. Baker HWG, Brindl J, Irvine DS et al (1996) Protective effect of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes. Fertil Steril 65:411-419
32. Naziroglu M, Cay M (2001) Protective role of intraperitoneally administered vitamin E and selenium on the antioxidative defense mechanisms in rats with diabetes induced by streptozotocin. Biol Trace Elem Res 79:149-159
33. Arthur JR, McKenzie RC, Beckett GJ (2003) Selenium in the immune system. J Nutr 135(5 suppl 1):1457s-1459s
34. Keen CL (1990) Zinc deficiency and immune function. Annu Rev Nutr 10:415-431
35. Harrison MD, Jones CE, Solioz M, Dameron CT (2000) Intracellular copper routing: the role of copper chaperones. Trends Biochem Sci 25(1):29-32
36. Sahin M, Cam H, Olgar S et al (2006) Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver. Mol Cell Biochem 291:155-160
37. Akturk O, Demirin H, Sutcu R et al (2006) The effects of diazinon on lipid peroxidation and antioxidant enzymes in rat heart and ameliorating role of vitamin E and vitamin C. Cell Biol Toxicol 22:455-461