Undetectable serum thyroglobulin due to negative interference of heterophile antibodies in relapsing thyroid carcinoma [6]

Clinical Chemistry

Volumn 53, Issue 10, 2007, Pages 1871-1872

  Giovanella, Luca ^a   Ghelfo, Antonella ^b  

^a ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND   (Switzerland)

^b OSPEDALE DI CIRCOLO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROPHILE ANTIBODY; RADIOACTIVE IODINE; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROTROPIN;

ADULT; ASPIRATION BIOPSY; CASE REPORT; CROSS REACTION; ECHOGRAPHY; FALSE NEGATIVE RESULT; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOASSAY; LETTER; NECK DISSECTION; RADIOISOTOPE THERAPY; RECURRENT CANCER; THYROGLOBULIN BLOOD LEVEL; THYROID CARCINOMA; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY;

ADULT; ANTIBODIES, HETEROPHILE; AUTOANTIBODIES; CARCINOMA, PAPILLARY; FALSE NEGATIVE REACTIONS; FEMALE; HUMANS; IMMUNOASSAY; LYMPHATIC METASTASIS; NEOPLASM RECURRENCE, LOCAL; SERUM; THYROGLOBULIN; THYROID NEOPLASMS;

EID: 34848918881     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.093229     Document Type: Letter

References (5)

1. Spencer CA, Bergoglio LM, Kazarosyan M, Fatemi S, LoPresti JS. Clinical impact of thyroglobulin (Tg) and Tg autoantibody method differences on the management of patients with differentiated thyroid carcinomas. J Clin Endocrinol Metab 2005;90:5566-75.
2. Preissner CM, O'Kane DJ, Singh RJ, Morris JC, Grebe SK. Phantoms in the assay tube: heterophile antibody interferences in serum thyroglobulin assay. J Clin Endocrinol Metab 2003;88:3069-74.
3. Giovanella L, Ceriani L, Keller F. How thyroglobulin recovery test really adds to anti-thyroglobulin antibodies quantitative assay when serum thyroglobulin is employed to manage differentiated thyroid carcinoma? Clin Chem 2006, http://clinchem.org/cgi/eletters/52/6/1196 (accessed May 2007).
4. Kricka LJ. Human anti-animal antibody interferences in immunological assays. Clin Chem 1999;45:942-56.
5. Boi F, Baghino G, Atzeni F, Lai ML, Faa G, Mariotti S. The diagnostic value for differentiated thyroid carcinoma metastases of thyroglobulin (Tg) measurement in washout fluid from fine-needle aspiration biopsy of neck lymph nodes is maintained in the presence of circulating anti-Tg antibodies. J Clin Endocrinol Metab 2006;91:1364-9.