Aeropin from the extremophile pyrobaculum aerophilum bypasses the serpin misfolding trap

Journal of Biological Chemistry

Volumn 282, Issue 37, 2007, Pages 26802-26809

  Cabrita, Lisa D ^a,b   Irving, James A ^a,c   Pearce, Mary C ^a   Whisstock, James C ^a   Bottomley, Stephen P ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AEROPIN; INHIBITORY ACTIVITY; MISFOLDING FATE; PROTEINASE INHIBITION;

AGGLOMERATION; CHARACTERIZATION; CHEMICAL STABILITY; DISEASES; ENZYME INHIBITION; KINETICS; OPTIMIZATION; PH EFFECTS;

BACTERIA;

AEROPIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; HYPERTHERMOPHILE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN STABILITY; PYROBACULUM; PYROBACULUM AEROPHILUM; THERMOSTABILITY;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; DISULFIDES; HEAT; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PYROBACULUM; SERINE PROTEINASE INHIBITORS; SERPINS;

ARCHAEA; PYROBACULUM AEROPHILUM;

EID: 34848911346     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705020200     Document Type: Article

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