Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis

Neurochemical Research

Volumn 32, Issue 11, 2007, Pages 1898-1905

  Galoyan, Armen A ^a   Krieglstein, Josef ^b,c   Klumpp, Susanne ^b   Danielian, Kristina E ^a   Galoian, Karine A ^d   Kremers, Wolfram ^c   Bezirganyan, Kristina B ^a   Davtyan, Tigran K ^a,e  

^a H Buniatian Institute of Biochemistry National Academy of Sciences of Armenia   (Armenia)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e Armenicum Research Centre Yerevan   (Armenia)

Author keywords

Bone marrow granulocytes; Hypothalamic proline rich polypeptide; Postnatal hippocampal cells; Staurosporine and doxorubicin induced apoptosis

Indexed keywords

ARGIPRESSIN; BRAIN PEPTIDE; DOXORUBICIN; PROLINE RICH PEPTIDE; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; BRAIN NERVE CELL; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; GRANULOCYTE; HYPOTHALAMUS; MONOCYTE; MYELOPOIESIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SURVIVAL RATE;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; DOXORUBICIN; HIPPOCAMPUS; NEURONS; PEPTIDES; RATS; STAUROSPORINE;

BOVINAE;

EID: 34848872202     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9379-9     Document Type: Article

References (39)

1. Galoyan AA (1996) New polypeptides of hypothalamus: isolation and primary structure. Proc NAS RA 96:555-570
2. Galoyan AA (1997) Biochemistry of novel cardioactive hormones and immune-modulators of the functional system neurosecretory hypothalamus-endocrine heart. Moscow, Nauka Publishers, p 240
3. Galoyan AA, Sarkissian JS, Kipriyan T, Sarkissian EJ, Sulkhanyan RM, Grigorian YK, Khachatrian TS (2000) Comparison of the protection against neuronal injury by hypothalamic peptides and by dexamethasone. Neurochem Res 25:1567-1578
4. Galoyan AA, Sarkissian JS, Kipriyan TK, Sarkissian EJ, Chavushyan E, Sulkhanyan RM, Meliksetyan IB, Abrahamyan SS, Grigorian YK, Avetisyan ZA, Otieva NA (2001) Protective effects of proline-rich peptides against cobra venom and trauma induced neuronal injury. Neurochem Res 26:1023-1038
5. Galoyan AA, Sarkissian JS, Chavushyan VA, Sulkhanyan RM, Avakyan ZE, Avetisyan ZA, Abrahamyan OD, Grigoryan YuKh (2005) PRP-1 protective effects of proline-rich peptides against central and peripheral neurodegeneration following N. Ischiadicus transection. Neurochem Res 30:487-505
6. Galoyan AA, Sarkissian JS, Chavushyan VA, Sulkhanyan RM, Avakyan ZE, Avetisyan ZA, Grigoryan YuKh, Abrahamyan OD (2005) Neuroprotective action of hypothalamic peptide PRP-1 at various time survival following spinal cord hemisection. Neurochem Res 30:507-525
7. Shakhlamov VA, Galoyan AA, Polyakova GN, Vahradyan HG, Simonian MA, Aghadjanov MI, Bogdanova JM, Altuchova VJ, Kondakova LJ (2002) Biochemical and ultrastructural equivalents of aluminum toxicosis and effect of proline-rich peptide of hypothalamus. Proc NAS RA 102(2):166-172
8. Galoyan AA, Shakhlamov VA, Aghadjanov MI, Vahradyan HG (2004) Hypothalamic proline-rich polypeptide protects brain neurons at aluminum neurotoxicosis. Neurochem Res 29:1349-1357
9. 14C-glucose utilization during crush syndrome. Neurochem Res 26:1023-1038
10. Galoyan A, Sarkissian JS, Chavushyan VA, Abrahamyan SS, Avakyan ZE, Vagradyan HG, Poghossyan MV, Grigoryan YuKh (2004) Study of the new hypothalamic proline-rich peptide (PRP-1) protective effect on morpho-functional changes in rat hippocampus using a model of Alzheimer's Disease Induced by intracerebroventricular injection of beta-Amyloid Peptide Aβ(25-35). Neurokhimya 21(4):265-288
11. Galoyan AA (2004) Brain neurosecretory cytokines: immune response and neuronal survival. Kluwer Academic/Plenum Publishers, NY, p 188
12. Aprikyan VS, Galoyan AA (1999) Immune-protective properties of a new hypothalamic polypeptide in bacterial pathologies. Med Sci Armenia 39:23-30
13. Aprikyan VS, Galoyan AA (1999) Antibacterial activity of a new hypothalamic peptide. Proc NAS RA 99:367-371
14. Galoyan AA, Aprikyan VS (2002) A new hypothalamic polypeptide is a regulator of myelopoiesis. Neurochem Res 27(N4):305-312
15. Davtyan TK, Muradyan EB, Avanessyan LA, Alexanyan YuT, Petrossyan HH, Galoyan AA (1998) The influence of biologically active hypothalamic polypeptides on interleukin-2-dependent functions of human lymphocytes in culture. Neurokhimiya 15:45-50
16. Davtyan TK, Manukyan HM, Mkrtchyan NR, Avetisyan SA, Galoyan AA (2005) Hypothalamic proline-rich peptide is a regulator of oxidative burst in human neutrophils and monocytes. NeuroImmunoModulation 12:270-284
17. Davtyan TK, Manukyan HM, Hakopyan GS, Mkrtchyan NR, Avetisyan SA, Galoyan AA (2005) Hypothalamic proline-rich polypeptide is an oxidative burst regulator. Neurochem Res 30:297-309
18. Davtyan TK, Avetisyan SA, Hakopyan GS, Galoyan AA (2006) Hypothalamic proline-rich polypeptide down-regulates LFA-1(CD11a/CD18) integrin expression on human neitrophils. Neurokhimya 23:77-81
19. Jellinger KA (2006) Challenges in neuronal apoptosis. Curr Alzheimer Res 3:377-391
20. Culmsee C, Landshamer S (2006) Molecular insights into mechanisms of the cell death program: role in the progression of neurodegenerative disorders. Curr Alzheimer Res 3:269-283
21. Loh KP, Huang SH, De Silva R, Tan BK, Zhu YZ (2006) Oxidative stress: apoptosis in neuronal injury. Curr Alzheimer Res 3:327-337
22. Onyango IG, Khan SM (2006) Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease. Curr Alzheimer Res 3:339-349
23. Ohyagi Y, Tabira T (2006) Intracellular amyloid beta-protein and its associated molecules in the pathogenesis of Alzheimer's disease. Mini Rev Med Chem 6(10):1075-1080
24. Galoyan AA, Terio N, Berg MJ, Marks N (2000) Effects of proline-rich peptide (PRP) derived from neurophysin-vasopressin associated glycoprotein on caspases of murine neuroblastoma: evidence for caspase-2 and caspase-6 activation. 2000. Neurokhimya 17:185-188
25. Leibrock J, Lottspeich F, Hohn A (1989) Molecular cloning and expression of brain-derived neurotrophic factor. Nature 341:149-152
26. Lindsay R (1994) Neurotrophic growth factor and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neuroprophic factor. Neurobiol Aging 15:249-251
27. Chekhonin V, Gurina O, Ryabukhin I, Savchenko E, Galoyan AA (2001) Immunochemical study of the effect of neurotrophins on the grap synthesis in astrocyte culture. Proceeding of the International Conference "Biochemical and Molecular-Biological aspects of the brain Immune system. Yerevan. Encyclopedia Armenic Publishing House
28. Burdick AD, Ivnitski-Steele ID, Lauer FT, Burchiel SW (2006) PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells. Carcinogenesis 27:2331-2340
29. Chauhan D, Pandey P, Hideshima T, Treon S, Raje N, Davies FE, Shima Y, Tai YT, Rosen S, Avraham S, Kharbanda S, Anderson KC (2000) SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells. J Biol Chem 275:27845-27850
30. Felsch JS, Cachero TG, Peralta EG (1998) Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor. Proc Natl Acad Sci USA 95:5051-5056
31. Melikova S, Dylla SJ, Verfaillie CM (2004) Phosphatidylinositol-3-kinase activation mediates proline-rich tyrosine kinase 2 phosphorylation and recruitment to beta1-integrins in human CD34+ cells. Exp Hematol 32:1051-1056
32. Dylla SJ, Deyle DR, Theunissen K, Padurean AM, Verfaillie CM (2004) Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. Exp Hematol 32:365-374
33. Hromas R, Radich J, Collins S (1993) PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells. Biochem Biophys Res Commun 195:976-983
34. Liao W, Ho CY, Yan YL, Postlethwait J, Stainier DY (2000) Hex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127:4303-4313
35. Eom Y-W, Kim MA, Park SS, Goo MJ, Kwon HJ, Sohn S, Kim W-H, Yoon G, Choi KS (2005) Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 24:4765-4777
36. Kalivendi SV, Kotamraju S, Zhao H, Joseph J, Kalyanaraman B (2001) Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase. J Biol Chem 276:47266-47276
37. Kaplinsky C, Lotem J, Sachs L (1996) Protection of human myeloid leukemic cells against doxorubicin-induced apoptosis by granulocyte-macrophage colony-stimulating factor and interleukin 3. Leukemia 10:460-465
38. Ferraro C, Quemeneur L, Prigent AF, Taverne C, Revillard JP, Bonnefoy-Berard N (2000) Anthracyclines trigger apoptosis of both G0-G1 and cycling peripheral blood lymphocytes and induce massive deletion of mature T and B cells. Cancer Res 60:1901-1907
39. Chow KU, Boehrer S, Bojunga J, Stieler M, Rummel MJ, Fauth F, Schneider B, Martin H, Hoelzer D, Weidmann E, Mitrou PS (2002) Induction of apoptosis by cladribine (2-CdA), gemcitabine and other chemotherapeutic drugs on CD34+/CD38+ and CD34+/CD38- hematopoietic progenitor cells: selective effects of doxorubicin and 2-CdA with protection of immature cells. Leuk Lymphoma 43:377-384