-
1
-
-
0033281771
-
How many more breast cancer predisposition genes are there?
-
138504 11250676 10.1186/bcr6
-
Easton DF How many more breast cancer predisposition genes are there? Breast Cancer Res 1999, 1:14-17. 138504 11250676 10.1186/bcr6
-
(1999)
Breast Cancer Res
, vol.1
, pp. 14-17
-
-
Easton, D.F.1
-
2
-
-
0037033733
-
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes
-
10.1038/sj.bjc.6600008 11857015
-
Antoniou AC Pharoah PD McMullan G Day NE Stratton MR Peto J Ponder BJ Easton DF A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes Br J Cancer 2002, 86:76-83. 10.1038/ sj.bjc.6600008 11857015
-
(2002)
Br J Cancer
, vol.86
, pp. 76-83
-
-
Antoniou, A.C.1
Pharoah, P.D.2
McMullan, G.3
Day, N.E.4
Stratton, M.R.5
Peto, J.6
Ponder, B.J.7
Easton, D.F.8
-
5
-
-
0142063079
-
Polygenic inheritance of breast cancer: Implications for design of association studies
-
10.1002/gepi.10261 14557987
-
Antoniou AC Easton DF Polygenic inheritance of breast cancer: Implications for design of association studies Genet Epidemiol 2003, 25:190-202. 10.1002/gepi.10261 14557987
-
(2003)
Genet Epidemiol
, vol.25
, pp. 190-202
-
-
Antoniou, A.C.1
Easton, D.F.2
-
6
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
10.1016/S1535-6108(03)00110-7 12781359
-
Bartek J Lukas J Chk1 and Chk2 kinases in checkpoint control and cancer Cancer Cell 2003, 3:421-429. 10.1016/S1535-6108(03)00110-7 12781359
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
7
-
-
18444379055
-
A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer
-
379177 12094328 10.1086/341943
-
Vahteristo P Bartkova J Eerola H Syrjakoski K Ojala S Kilpivaara O Tamminen A Kononen J Aittomaki K Heikkila P Holli K Blomqvist C Bartek J Kallioniemi OP Nevanlinna H A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer Am J Hum Genet 2002, 71:432-438. 379177 12094328 10.1086/341943
-
(2002)
Am J Hum Genet
, vol.71
, pp. 432-438
-
-
Vahteristo, P.1
Bartkova, J.2
Eerola, H.3
Syrjakoski, K.4
Ojala, S.5
Kilpivaara, O.6
Tamminen, A.7
Kononen, J.8
Aittomaki, K.9
Heikkila, P.10
Holli, K.11
Blomqvist, C.12
Bartek, J.13
Kallioniemi, O.P.14
Nevanlinna, H.15
-
8
-
-
18544389716
-
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
-
10.1038/ng879 11967536
-
Meijers-Heijboer H van den Ouweland A Klijn J Wasielewski M de Snoo A Oldenburg R Hollestelle A Houben M Crepin E van Veghel-Plandsoen M Elstrodt F van Duijn C Bartels C Meijers C Schutte M McGuffog L Thompson D Easton D Sodha N Seal S Barfoot R Mangion J Chang-Claude J Eccles D Eeles R Evans DG Houlston R Murday V Narod S Peretz T Peto J Phelan C Zhang HX Szabo C Devilee P Goldgar D Futreal PA Nathanson KL Weber B Rahman N Stratton MR Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations Nat Genet 2002, 31:55-59. 10.1038/ng879 11967536
-
(2002)
Nat Genet
, vol.31
, pp. 55-59
-
-
Meijers-Heijboer, H.1
van den Ouweland, A.2
Klijn, J.3
Wasielewski, M.4
de Snoo, A.5
Oldenburg, R.6
Hollestelle, A.7
Houben, M.8
Crepin, E.9
van Veghel-Plandsoen, M.10
Elstrodt, F.11
van Duijn, C.12
Bartels, C.13
Meijers, C.14
Schutte, M.15
McGuffog, L.16
Thompson, D.17
Easton, D.18
Sodha, N.19
Seal, S.20
Barfoot, R.21
Mangion, J.22
Chang-Claude, J.23
Eccles, D.24
Eeles, R.25
Evans, D.G.26
Houlston, R.27
Murday, V.28
Narod, S.29
Peretz, T.30
Peto, J.31
Phelan, C.32
Zhang, H.X.33
Szabo, C.34
Devilee, P.35
Goldgar, D.36
Futreal, P.A.37
Nathanson, K.L.38
Weber, B.39
Rahman, N.40
Stratton, M.R.41
more..
-
9
-
-
0347626108
-
The CHEK2 * 1100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families
-
14678969
-
Oldenburg RA Kroeze-Jansema K Kraan J Morreau H Klijn JG Hoogerbrugge N Ligtenberg MJ van Asperen CJ Vasen HF Meijers C Meijers-Heijboer H de Bock TH Cornelisse CJ Devilee P The CHEK2*1100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families Cancer Res 2003, 63:8153-8157. 14678969
-
(2003)
Cancer Res
, vol.63
, pp. 8153-8157
-
-
Oldenburg, R.A.1
Kroeze-Jansema, K.2
Kraan, J.3
Morreau, H.4
Klijn, J.G.5
Hoogerbrugge, N.6
Ligtenberg, M.J.7
van Asperen, C.J.8
Vasen, H.F.9
Meijers, C.10
Meijers-Heijboer, H.11
de Bock, T.H.12
Cornelisse, C.J.13
Devilee, P.14
-
10
-
-
3042582651
-
CHEK2* 1100delC and susceptibility to breast cancer: A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies
-
1182081 15122511 10.1086/421251
-
CHEK2*1100delC and susceptibility to breast cancer: A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies Am J Hum Genet 2004, 74:1175-1182. 1182081 15122511 10.1086/421251
-
(2004)
Am J Hum Genet
, vol.74
, pp. 1175-1182
-
-
-
11
-
-
35348918445
-
A molecular study on familial breast cancer
-
Karolinska Hospital Stockholm, Karolinska Institute
-
Lindblom A A molecular study on familial breast cancer Departments of Clinical Genetics and Oncology, Karolinska Hospital Stockholm, Karolinska Institute 1993
-
(1993)
Departments of Clinical Genetics and Oncology
-
-
Lindblom, A.1
-
12
-
-
14444288269
-
A screening for BRCA1 mutations in breast and breast-ovarian cancer families from the Stockholm region
-
9192828
-
Zelada-Hedman M Wasteson Arver B Claro A Chen J Werelius B Kok H Sandelin K Hakansson S Andersen TI Borg A Borresen Dale AL Lindblom A A screening for BRCA1 mutations in breast and breast-ovarian cancer families from the Stockholm region Cancer Res 1997, 57:2474-2477. 9192828
-
(1997)
Cancer Res
, vol.57
, pp. 2474-2477
-
-
Zelada-Hedman, M.1
Wasteson Arver, B.2
Claro, A.3
Chen, J.4
Werelius, B.5
Kok, H.6
Sandelin, K.7
Hakansson, S.8
Andersen, T.I.9
Borg, A.10
Borresen Dale, A.L.11
Lindblom, A.12
-
14
-
-
4143060219
-
BRCA1 mutations in a population-based study of breast cancer in Stockholm County
-
15345109
-
Margolin S Werelius B Fornander T Lindblom A BRCA1 mutations in a population-based study of breast cancer in Stockholm County Genet Test 2004, 8:127-132. 15345109
-
(2004)
Genet Test
, vol.8
, pp. 127-132
-
-
Margolin, S.1
Werelius, B.2
Fornander, T.3
Lindblom, A.4
-
15
-
-
6344283026
-
CHEK2:1100delC and female breast cancer in the United States
-
10.1002/ijc.20439 15382084
-
Mateus Pereira LH Sigurdson AJ Doody MM Pineda MA Alexander BH Greene MH Struewing JP CHEK2:1100delC and female breast cancer in the United States Int J Cancer 2004, 112:541-543. 10.1002/ijc.20439 15382084
-
(2004)
Int J Cancer
, vol.112
, pp. 541-543
-
-
Mateus Pereira, L.H.1
Sigurdson, A.J.2
Doody, M.M.3
Pineda, M.A.4
Alexander, B.H.5
Greene, M.H.6
Struewing, J.P.7
-
16
-
-
0038406108
-
The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype
-
1180284 12690581 10.1086/375121
-
Meijers-Heijboer H Wijnen J Vasen H Wasielewski M Wagner A Hollestelle A Elstrodt F van den Bos R de Snoo A Fat GT Brekelmans C Jagmohan S Franken P Verkuijlen P van den Ouweland A Chapman P Tops C Moslein G Burn J Lynch H Klijn J Fodde R Schutte M The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype Am J Hum Genet 2003, 72:1308-1314. 1180284 12690581 10.1086/ 375121
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1308-1314
-
-
Meijers-Heijboer, H.1
Wijnen, J.2
Vasen, H.3
Wasielewski, M.4
Wagner, A.5
Hollestelle, A.6
Elstrodt, F.7
van den Bos, R.8
de Snoo, A.9
Fat, G.T.10
Brekelmans, C.11
Jagmohan, S.12
Franken, P.13
Verkuijlen, P.14
van den Ouweland, A.15
Chapman, P.16
Tops, C.17
Moslein, G.18
Burn, J.19
Lynch, H.20
Klijn, J.21
Fodde, R.22
Schutte, M.23
more..
-
17
-
-
2542449310
-
Frequency of CHEK2* 1100delC in New York breast cancer cases and controls
-
149355 12529183 10.1186/1471-2350-4-1
-
Offit K Pierce H Kirchhoff T Kolachana P Rapaport B Gregersen P Johnson S Yossepowitch O Huang H Satagopan J Robson M Scheuer L Nafa K Ellis N Frequency of CHEK2* 1100delC in New York breast cancer cases and controls BMC Med Genet 2003, 4:1. 149355 12529183 10.1186/1471-2350-4-1
-
(2003)
BMC Med Genet
, vol.4
, pp. 1
-
-
Offit, K.1
Pierce, H.2
Kirchhoff, T.3
Kolachana, P.4
Rapaport, B.5
Gregersen, P.6
Johnson, S.7
Yossepowitch, O.8
Huang, H.9
Satagopan, J.10
Robson, M.11
Scheuer, L.12
Nafa, K.13
Ellis, N.14
-
18
-
-
14944355906
-
Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: Functional analysis in heterozygous individuals
-
10.1038/sj.bjc.6602381 15700044
-
Jekimovs CR Chen X Arnold J Gatei M Richard DJ Spurdle AB Khanna KK Chenevix-Trench G Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: Functional analysis in heterozygous individuals Br J Cancer 2005, 92:784-790. 10.1038/ sj.bjc.6602381 15700044
-
(2005)
Br J Cancer
, vol.92
, pp. 784-790
-
-
Jekimovs, C.R.1
Chen, X.2
Arnold, J.3
Gatei, M.4
Richard, D.J.5
Spurdle, A.B.6
Khanna, K.K.7
Chenevix-Trench, G.8
-
19
-
-
20244378377
-
The CHEK2 c.1100delC germline mutation rarely contributes to breast cancer development in the Czech Republic
-
10.1007/s10549-004-4023-8 15803363
-
Kleibl Z Novotny J Bezdickova D Malik R Kleiblova P Foretova L Petruzelka L Ilencikova D Cinek P Pohlreich P The CHEK2 c.1100delC germline mutation rarely contributes to breast cancer development in the Czech Republic Breast Cancer Res Treat 2005, 90:165-167. 10.1007/ s10549-004-4023-8 15803363
-
(2005)
Breast Cancer Res Treat
, vol.90
, pp. 165-167
-
-
Kleibl, Z.1
Novotny, J.2
Bezdickova, D.3
Malik, R.4
Kleiblova, P.5
Foretova, L.6
Petruzelka, L.7
Ilencikova, D.8
Cinek, P.9
Pohlreich, P.10
-
20
-
-
0344825130
-
The breast cancer low-penetrance allele 1100delC in the CHEK2 gene is not present in Spanish familial breast cancer population
-
10.1002/ijc.11414 14618615
-
Osorio A Rodriguez-Lopez R Diez O de la Hoya M Ignacio Martinez J Vega A Esteban-Cardenosa E Alonso C Caldes T Benitez J The breast cancer low-penetrance allele 1100delC in the CHEK2 gene is not present in Spanish familial breast cancer population Int J Cancer 2004, 108:54-56. 10.1002/ijc.11414 14618615
-
(2004)
Int J Cancer
, vol.108
, pp. 54-56
-
-
Osorio, A.1
Rodriguez-Lopez, R.2
Diez, O.3
de la Hoya, M.4
Ignacio Martinez, J.5
Vega, A.6
Esteban-Cardenosa, E.7
Alonso, C.8
Caldes, T.9
Benitez, J.10
-
21
-
-
32144449216
-
CHEK2* 1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden
-
10.1080/00365590500368518 16452051
-
Wagenius M Borg A Johansson L Giwercman A Bratt O CHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden Scand J Urol Nephrol 2006, 40:23-25. 10.1080/ 00365590500368518 16452051
-
(2006)
Scand J Urol Nephrol
, vol.40
, pp. 23-25
-
-
Wagenius, M.1
Borg, A.2
Johansson, L.3
Giwercman, A.4
Bratt, O.5
-
22
-
-
33645471674
-
CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum
-
1421428 16539695 10.1186/1471-2407-6-64
-
Isinger A Bhat M Borg A Nilbert M CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum BMC Cancer 2006, 6:64. 1421428 16539695 10.1186/1471-2407-6-64
-
(2006)
BMC Cancer
, vol.6
, pp. 64
-
-
Isinger, A.1
Bhat, M.2
Borg, A.3
Nilbert, M.4
-
23
-
-
33745627058
-
Linkage disequilibrium mapping of CHEK2: Common variation and breast cancer risk
-
1457009 16671833 10.1371/journal.pmed.0030168
-
Einarsdottir K Humphreys K Bonnard C Palmgren J Iles MM Sjolander A Li Y Chia KS Liu ET Hall P Liu J Wedren S Linkage disequilibrium mapping of CHEK2: Common variation and breast cancer risk PLoS Med 2006, 3:e168. 1457009 16671833 10.1371/journal.pmed.0030168
-
(2006)
PLoS Med
, vol.3
-
-
Einarsdottir, K.1
Humphreys, K.2
Bonnard, C.3
Palmgren, J.4
Iles, M.M.5
Sjolander, A.6
Li, Y.7
Chia, K.S.8
Liu, E.T.9
Hall, P.10
Liu, J.11
Wedren, S.12
-
24
-
-
6344261987
-
Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2* 1100delC variant
-
10.1136/jmg.2004.019737 15466005
-
de Bock GH Schutte M Krol-Warmerdam EM Seynaeve C Blom J Brekelmans CT Meijers-Heijboer H van Asperen CJ Cornelisse CJ Devilee P Tollenaar RA Klijn JG Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2* 1100delC variant J Med Genet 2004, 41:731-735. 10.1136/jmg.2004.019737 15466005
-
(2004)
J Med Genet
, vol.41
, pp. 731-735
-
-
de Bock, G.H.1
Schutte, M.2
Krol-Warmerdam, E.M.3
Seynaeve, C.4
Blom, J.5
Brekelmans, C.T.6
Meijers-Heijboer, H.7
van Asperen, C.J.8
Cornelisse, C.J.9
Devilee, P.10
Tollenaar, R.A.11
Klijn, J.G.12
-
25
-
-
28244457585
-
German populations with infrequent CHEK2* 1100delC and minor associations with early-onset and familial breast cancer
-
10.1016/j.ejca.2005.04.049 16239104
-
Rasid MU Jakubowska A Justenhoven C Harth V Pesch B Baisch C Pierl CB Bruning T Ko Y Benner A Wichmann HE Brauch H Hamann U German populations with infrequent CHEK2* 1100delC and minor associations with early-onset and familial breast cancer Eur J Cancer 2005, 41:2896-2903. 10.1016/j.ejca.2005.04.049 16239104
-
(2005)
Eur J Cancer
, vol.41
, pp. 2896-2903
-
-
Rashid, M.U.1
Jakubowska, A.2
Justenhoven, C.3
Harth, V.4
Pesch, B.5
Baisch, C.6
Pierl, C.B.7
Bruning, T.8
Ko, Y.9
Benner, A.10
Wichmann, H.E.11
Brauch, H.12
Hamann, U.13
-
27
-
-
23644442729
-
No increased susceptibility to breast cancer from combined CHEK2 1100delC genotype and the HLA class III region risk factors
-
10.1016/j.ejca.2005.04.035 16043347
-
de Jong MM Nolte IM Te Meerman GJ van der Graaf WT Oosterom E Bruinenberg M Steege G Oosterwijk JC van der Hout AH Boezen HM Schaapveld M Kleibeuker JH de Vries EG No increased susceptibility to breast cancer from combined CHEK2 1100delC genotype and the HLA class III region risk factors Eur J Cancer 2005, 41:1819-1823. 10.1016/ j.ejca.2005.04.035 16043347
-
(2005)
Eur J Cancer
, vol.41
, pp. 1819-1823
-
-
de Jong, M.M.1
Nolte, I.M.2
Te Meerman, G.J.3
van der Graaf, W.T.4
Oosterom, E.5
Bruinenberg, M.6
Steege, G.7
Oosterwijk, J.C.8
van der Hout, A.H.9
Boezen, H.M.10
Schaapveld, M.11
Kleibeuker, J.H.12
de Vries, E.G.13
-
28
-
-
19944424422
-
Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients
-
10.1002/ijc.20638 15472904
-
Kilpivaara O Bartkova J Eerola H Syrjakoski K Vahteristo P Lukas J Blomqvist C Holli K Heikkila P Sauter G Kallioniemi OP Bartek J Nevanlinna H Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients Int J Cancer 2005, 113:575-580. 10.1002/ijc.20638 15472904
-
(2005)
Int J Cancer
, vol.113
, pp. 575-580
-
-
Kilpivaara, O.1
Bartkova, J.2
Eerola, H.3
Syrjakoski, K.4
Vahteristo, P.5
Lukas, J.6
Blomqvist, C.7
Holli, K.8
Heikkila, P.9
Sauter, G.10
Kallioniemi, O.P.11
Bartek, J.12
Nevanlinna, H.13
-
29
-
-
0033601346
-
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
-
10.1126/science.286.5449.2528 10617473
-
Bell DW Varley JM Szydlo TE Kang DH Wahrer DC Shannon KE Lubratovich M Verselis SJ Isselbacher KJ Fraumeni JF Birch JM Li FP Garber JE Haber DA Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome Science 1999, 286:2528-2531. 10.1126/science.286.5449.2528 10617473
-
(1999)
Science
, vol.286
, pp. 2528-2531
-
-
Bell, D.W.1
Varley, J.M.2
Szydlo, T.E.3
Kang, D.H.4
Wahrer, D.C.5
Shannon, K.E.6
Lubratovich, M.7
Verselis, S.J.8
Isselbacher, K.J.9
Fraumeni, J.F.10
Birch, J.M.11
Li, F.P.12
Garber, J.E.13
Haber, D.A.14
-
30
-
-
2442476240
-
Limited relevance of the CHEK2 gene in hereditary breast cancer
-
10.1002/ijc.20073 15095295
-
Dufault MR Betz B Wappenschmidt B Hofmann W Bandick K Golla A Pietschmann A Nestle-Kramling C Rhiem K Huttner C von Lindern C Dall P Kiechle M Untch M Jonat W Meindl A Scherneck S Niederacher D Schmutzler RK Arnold N Limited relevance of the CHEK2 gene in hereditary breast cancer Int J Cancer 2004, 110:320-325. 10.1002/ijc.20073 15095295
-
(2004)
Int J Cancer
, vol.110
, pp. 320-325
-
-
Dufault, M.R.1
Betz, B.2
Wappenschmidt, B.3
Hofmann, W.4
Bandick, K.5
Golla, A.6
Pietschmann, A.7
Nestle-Kramling, C.8
Rhiem, K.9
Huttner, C.10
von Lindern, C.11
Dall, P.12
Kiechle, M.13
Untch, M.14
Jonat, W.15
Meindl, A.16
Scherneck, S.17
Niederacher, D.18
Schmutzler, R.K.19
Arnold, N.20
more..
-
31
-
-
18744372122
-
Increasing evidence that germline mutations in CHEK2 do not cause Li-Fraumeni syndrome
-
10.1002/humu.10136 12442270
-
Sodha N Houlston RS Bullock S Yuille MA Chu C Turner G Eeles RA Increasing evidence that germline mutations in CHEK2 do not cause Li-Fraumeni syndrome Hum Mutat 2002, 20:460-462. 10.1002/humu.10136 12442270
-
(2002)
Hum Mutat
, vol.20
, pp. 460-462
-
-
Sodha, N.1
Houlston, R.S.2
Bullock, S.3
Yuille, M.A.4
Chu, C.5
Turner, G.6
Eeles, R.A.7
|