Evaluating virulence of waterborne and clinical Aeromonas isolates using gene expression and mortality in neonatal mice followed by assessing cell culture's ability to predict virulence based on transcriptional response

Journal of Applied Microbiology

Volumn 103, Issue 4, 2007, Pages 811-820

  Hayes, S L ^a   Rodgers, M R ^a   Lye, D J ^b   Stelma, G N ^b   McKinstry, C A ^c   Malard, J M ^c   Vesper, S J ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Aeromonas; Gene expression; Host response; Virulence

Indexed keywords

CELL DEATH; CELL SIGNALING; HEALTH RISKS; MAMMALS; RISK ASSESSMENT; TRANSCRIPTION;

AEROMONAS; AEROMONAS SPP; GENE RESPONSE; GENES EXPRESSION; HOST RESPONSE; INTESTINAL CELLS; NEONATAL MOUSE; SIMPLEST MODEL SYSTEMS; TRANSCRIPTIONAL RESPONSE; VIRULENCE;

CELL CULTURE;

CHEMOKINE; GENE PRODUCT; MESSENGER RNA;

BACTERIAL DISEASE; BACTERIUM; BIOASSAY; GENE EXPRESSION; HEALTH RISK; INFECTIOUS DISEASE; MORTALITY; PUBLIC HEALTH; RISK ASSESSMENT; RODENT; VIRULENCE; WATERBORNE DISEASE;

AEROMONAS; ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; HOST RESISTANCE; IMMUNE RESPONSE; INFECTION; INTESTINE CELL; MICROARRAY ANALYSIS; MORTALITY; MOUSE; NEWBORN; NONHUMAN; ONCOGENE; PREDICTION; RNA EXTRACTION; TRANSCRIPTION REGULATION; UPREGULATION;

AEROMONAS; ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE; MUS;

EID: 34848831742     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.2007.03318.x     Document Type: Article

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