Chronic rhinosinusitis with nasal polyps is associated with decreased expression of mucosal interleukin 22 receptor

Laryngoscope

Volumn 117, Issue 10, 2007, Pages 1839-1843

  Ramanathan Jr , Murugappan ^a   Spannhake, Ernst W ^b   Lane, Andrew P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Chronic sinusitis; IL 22; Innate immune

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; DECONGESTIVE AGENT; INTERLEUKIN 22; INTERLEUKIN 22 RECEPTOR; INTERLEUKIN RECEPTOR; METHYLPREDNISOLONE; MUCOLYTIC AGENT; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOSCOPIC SURGERY; EPITHELIUM CELL; ETHMOID SINUS; FLOW CYTOMETRY; HUMAN; NOSE MUCOSA; NOSE POLYP; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECURRENT DISEASE; RHINOSINUSITIS; RNA EXTRACTION;

CHRONIC DISEASE; DNA PRIMERS; FLOW CYTOMETRY; HUMANS; NASAL MUCOSA; NASAL POLYPS; PROSPECTIVE STUDIES; RECEPTORS, INTERLEUKIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SINUSITIS;

EID: 34848831481     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MLG.0b013e31811edd4f     Document Type: Article

References (19)

1. Anand VK. Epidemiology and economic impact of rhinosinusitis. Ann Otol Rhinol Laryngol 2004;193(Suppl):3-5.
2. Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: establishing definitions for clinical research and patient care. Otolaryngol Head Neck Surg 2004;131(Suppl 6):S1-62.
3. Alexopoulou L, Kontoyiannis D. Contribution of microbial-associated molecules in innate mucosal responses. Cell Mol Life Sci 2005;62:1349-1358.
4. Ramanathan M Jr, Lane AP. Innate immunity of the sinonasal cavity and its role in chronic rhinosinusitis. Otolaryngol Head Neck Surg 2007;136:348-356.
5. Lane AP, Truong-Tran QA, Myers A, Bickel C, Schleimer RP. Serum amyloid A, properdin, complement 3, and toll-like receptors are expressed locally in human sinonasal tissue. Am J Rhinol 2006;20:117-123.
6. Gurney AL. IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues. Int Immunopharmacol 2004;4:669-677.
7. Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity 2004;21:241-254.
8. Wolk K, Witte E, Wallace E, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006;36:1309-1323.
9. Brand S, Beigel F, Olszak T, et al. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 2006;290:G827-838.
10. Lane AP, Saatian B, Yu XY, Spannhake EW. mRNA for genes associated with antigen presentation are expressed by human middle meatal epithelial cells in culture. Laryngoscope 2004;114:1827-1832.
11. Bachert C, Gevaert P, Van Cauwenberge P. Staphylococcus aureus enterotoxins: a key in airway disease? Allergy. 2002;57:480-487.
12. Cryer J, Schipor I, Perloff JR, Palmer JN. Evidence of bacterial biofilms in human chronic sinusitis. ORL J Otorhinolaryngol Relat Spec 2004;66:155-158.
13. Ponikau JU, Sherris DA, Kephart GM, Adolphson C, Kita H. The role of ubiquitous airborne fungi in chronic rhinosinusitis. Clin Rev Allergy Immunol 2006;30:187-194.
14. Andersen JM, Al-Khairy D, Ingalls RR. Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens. Biol Reprod 2006;74:824-831.
15. Selsted ME, Ouellette AJ. Mammalian defensins in the antimicrobial immune response. Nat Immunol 2005;6:551-557.
16. Ikeuchi H, Kuroiwa T, Hiramatsu N, Kaneko Y, Hiromura K, Ueki K, Nojima Y. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum 2005;52:1037-1046.
17. Whittington HA, Armstrong L, Uppington KM, Millar AB. Interleukin-22: a potential immunomodulatory molecule in the lung. Am J Respir Cell Mol Biol 2004;31:220-226.
18. Lane AP, Truong-Tran QA, Schleimer RP. Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polyps. Am J Rhinol 2006;20:138-144.
19. Bernstein JM, Kansal R. Superantigen hypothesis for the early development of chronic hyperplastic sinusitis with massive nasal polyposis. Curr Opin Otolaryngol Head Neck Surg 2005;13:39-44.