Intrarenal cytokine and chemokine gene expression and kidney graft outcome

Kidney and Blood Pressure Research

Volumn 30, Issue 5, 2007, Pages 273-282

  Hribova, Petra ^a   Lacha, Jiri ^a   Kotsch, Katja ^b   Volk, Hans Dieter ^b   Brabcova, Irena ^a   Skibova, Jelena ^a   Vitko, Stefan ^a   Viklicky, Ondrej ^a  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Chemokines; Chronic allograft nephropathy; Cytokines; Gene expression; Kidney transplantation; Proteinuria

Indexed keywords

CHEMOKINE; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE EXPRESSION; GRAFT FAILURE; GRAFT RECIPIENT; HUMAN; KAPLAN MEIER METHOD; KIDNEY GRAFT; MALE; PRIORITY JOURNAL; PROTEINURIA; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; UPREGULATION;

ADULT; CHEMOKINES; CYTOKINES; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 34748917049     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000105134     Document Type: Article

References (51)

1. Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B: Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am J Transplant 2004;4:378-383.
2. Carpenter CB: Long-term failure of renal transplants: adding insult to injury. Kidney Int Suppl 1995;50:S40-S44.
3. Paul LC: Chronic renal transplant loss. Kidney Int 1995;47:1491-1499.
4. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, Croker BP, Demetris AJ, Drachenberg CB, Fogo AB, Furness P, Gaber LW, Gibson IW, Glotz D, Goldberg JC, Grande J, Halloran PF, Hansen HE, Hartley B, Hayry PJ, Hill CM, Hoffman EO, Hunsicker LG, Lindblad AS, Marcussen N, Mihatsch MJ, Nadasdy T, Nickerson P, Olsen TS, Papadimitriou JC, Randhawa PS, Rayner DC, Roberts I, Rose S, Rush D, Salinas-Madrigal L, Salomon DR, Sund S, Taskinen E, Trpkov K, Yamaguchi Y: The Banff 97 working classification of renal allograft pathology. Kidney Int 1999;55:713-723.
5. Solez K, Axelsen RA, Benediktsson H, Burdick JF, Cohen AH, Colvin RB, Croker BP, Droz D, Dunnill MS, Halloran PF: International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology. Kidney Int 1993; 44:411-422.
6. Halloran PF: Call for revolution: a new approach to describing allograft deterioration. Am J Transplant 2002;2:195-200.
7. Tejani A, Ho PL, Emmett L, Stablein DM: Reduction in acute rejections decreases chronic rejection graft failure in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Am J Transplant 2002;2:142-147.
8. Tullius SG, Tilney NL: Both alloantigen-dependent and -independent factors influence chronic allograft rejection. Transplantation 1995;59:313-318.
9. Chapman JR, O'Connell PJ, Nankivell BJ: Chronic renal allograft dysfunction. J Am Soc Nephrol 2005;16:3015-3026.
10. Adams AB, Larsen CP, Pearson TC, Newell KA: The role of TNF receptor and TNF superfamily molecules in organ transplantation. Am J Transplant 2002;2:12-18.
11. Baan CC, Weimar W: Intragraft cytokine gene expression: implications for clinical transplantation. Transpl Int 1998;11:169-180.
12. Border WA, Noble NA: Transforming growth factor-β in tissue fibrosis. N Engl J Med 1994;331:1286-1292.
13. Noronha IL, Eberlein-Gonska M, Hartley B, Stephens S, Cameron JS, Waldherr R: In situ expression of tumor necrosis factor-α, interferon-γ, and interleukin-2 receptors in renal allograft biopsies. Transplantation 1992;54: 1017-1024.
14. Paul LC, Saito K, Davidoff A, Benediktsson H: Growth factor transcripts in rat renal transplants. Am J Kidney Dis 1996;28:441-450.
15. Hancock WH, Whitley WD, Tullius SG, Heemann UW, Wasowska B, Baldwin WM, 3rd, Tilney NL: Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts. Transplantation 1993;56:643-650.
16. Nadeau KC, Azuma H, Tilney NL: Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci USA 1995;92:8729-8733.
17. Azuma H, Heemann UW, Tullius SG, Tilney NL: Cytokines and adhesion molecules in chronic rejection. Clin Transplant 1994;8: 168-180.
18. Song E, Zou H, Yao Y, Proudfoot A, Antus B, Liu S, Jens L, Heemann U: Early application of Met-RANTES ameliorates chronic allograft nephropathy. Kidney Int 2002;61: 676-685.
19. Melk A, Henne T, Kollmar T, Strehlau J, Latta K, Offner G, Jhangri GS, Ehrich JH, Von Schnakenburg C: Cytokine single nucleotide polymorphisms and intrarenal gene expression in chronic allograft nephropathy in children. Kidney Int 2003;64:314-320.
20. Strehlau J, Pavlakis M, Lipman M, Shapiro M, Vasconcellos L, Harmon W, Strom TB: Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc Natl Acad Sci USA 1997;94:695-700.
21. 1, TNF-α, IL-1β, and IL-6 in the renal artery wall of chronically rejected human renal allografts. Transplant Proc 2002; 34:3176-3179.
22. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
23. Platzer C, Ode-Hakim S, Reinke P, Docke WD, Ewert R, Volk HD: Quantitative PCR analysis of cytokine transcription patterns in peripheral mononuclear cells after anti-CD3 rejection therapy using two novel multispecific competitor fragments. Transplantation 1994;58:264-268.
24. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR: The natural history of chronic allograft nephropathy. N Engl J Med 2003;349:2326-2333.
25. Arias M, Fernandez-Fresnedo G, Rodrigo E, Ruiz JC, Gonzalez-Cotorruelo J, Gomez-Alamillo C: Non-immunologic intervention in chronic allograft nephropathy. Kidney Int Suppl 2005:S118-S123.
26. Joosten SA, Sijpkens YW, van Kooten C, Paul LC: Chronic renal allograft rejection: pathophysiologic considerations. Kidney Int 2005; 68:1-13.
27. Massy ZA, Guijarro C, Wiederkehr MR, Ma JZ, Kasiske BL: Chronic renal allograft rejection: immunologic and non-immunologic risk factors. Kidney Int 1996;49:518-524.
28. Suthanthiran M: Molecular analyses of human renal allografts: differential intragraft gene expression during rejection. Kidney Int Suppl 1997;58:S15-S21.
29. Orosz CG: Considerations regarding the contributions of B cells to chronic allograft rejection in experimental animal models. J Heart Lung Transplant 2000;19:634-637.
30. Paul LC: Chronic allograft nephropathy: an update. Kidney Int 1999;56:783-793.
31. 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy. Kidney Int 1996;49:1297-1303.
32. Sharma VK, Ding R, Li B, Bologa RM, Lagman M, Eduafo A, Edouard P, Mouradian J, Strom TB, Suthanthiran M: Molecular correlates of human renal allograft rejection. Transplant Proc 1998;30:2364-2366.
33. Shihab FS, Yamamoto T, Nast CC, Cohen AH, Noble NA, Gold LI, Border WA: Transforming growth factor-β and matrix protein expression in acute and chronic rejection of human renal allografts. J Am Soc Nephrol 1995;6:286-294.
34. 1 expression and rejection grade. Transplantation 2001;71:306-313.
35. Robertson H, Morley AR, Talbot D, Callanan K, Kirby JA: Renal allograft rejection: β-chemokine involvement in the development of tubulitis. Transplantation 2000;69: 684-687.
36. Shimizu A, Yamada K, Sachs DH, Colvin RB: Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis. Kidney Int 2002;61:1867-1879.
37. Peterson JC, Adler S, Burkart JM, Greene T, Hebert LA, Hunsicker LG, King AJ, Klahr S, Massry SG, Seifter JL: Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study. Ann Intern Med 1995; 123:754-762.
38. Remuzzi G, Bertani T: Pathophysiology of progressive nephropathies. N Engl J Med 1998;339:1448-1456.
39. Ruggenenti P, Perna A, Mosconi L, Matalone M, Pisoni R, Gaspari F, Remuzzi G: Proteinuria predicts end-stage renal failure in nondiabetic chronic nephropathies. The 'Gruppo Italiano di Studi Epidemiologici in Nefrologia' (GISEN). Kidney Int Suppl 1997; 63:S54-S57.
40. Sheerin NS, Sacks SH: Chronic interstitial damage in proteinuria. Does complement mediate tubulointerstitial injury? Kidney Blood Press Res 1999;22:47-52.
41. Wang S, LaPage J, Hirschberg R: Proteinuria and progression of chronic renal disease. Kidney Blood Press Res 2000;23:167-169.
42. Iwano M, Neilson EG: Mechanisms of tubulointerstitial fibrosis. Curr Opin Nephrol Hypertens 2004;13:279-284.
43. Wang SN, LaPage J, Hirschberg R: Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy. Kidney Int 2000;57:1002-1014.
44. Abbate M, Remuzzi G: Proteinuria as a mediator of tubulointerstitial injury. Kidney Blood Press Res 1999;22:37-46.
45. 1 mRNA upregulation influences chronic renal allograft dysfunction. Kidney Int 2006;69:1872-1879.
46. Hohage H, Kleyer U, Bruckner D, August C, Zidek W, Spieker C: Influence of proteinuria on long-term transplant survival in kidney transplant recipients. Nephron 1997;75:160-165.
47. McLaren AJ, Fuggle SV, Welsh KI, Gray DW, Morris PJ: Chronic allograft failure in human renal transplantation: a multivariate risk factor analysis. Ann Surg 2000;232:98-103.
48. Diegmann J, Junker K, Gerstmayer B, Bosio A, Hindermann W, Rosenhahn J, von Eggeling F: Identification of CD70 as a diagnostic biomarker for clear cell renal cell carcinoma by gene expression profiling, real-time RT-PCR and immunohistochemistry. Eur J Cancer 2005;41:1794-1801.
49. Gao R, Lu Y, Xin YP, Zhang XH, Wang J, Li YP: The effects of different immunosuppressants on chronic allograft nephropathy by affecting the transforming growth factor-β and Smads signal pathways. Transplant Proc 2006;38:2154-2157.
50. Mu W, Ouyang X, Agarwal A, Zhang L, Long DA, Cruz PE, Roncal CA, Glushakova OY, Chiodo VA, Atkinson MA, Hauswirth WW, Flotte TR, Rodriguez-Iturbe B, Johnson RJ: IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol 2005;16:3651-3660.
51. Kim TW, Ji JW, Chang HG, Kim MO, Ryoo ZY, Park IK, Kim SJ: 3′-Half of the thrombopoietin cDNA confers higher expression of erythropoietin at the RNA level but not at the protein level. Mol Cells 2005;19:198-204.