Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis

FEBS Journal

Volumn 274, Issue 19, 2007, Pages 5167-5174

  Carrigan, John B ^a   Engel, Paul C ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Coenzyme specificity; Glutamate dehydrogenase; NAD(P)+; Nicotinamide nucleotides; Site directed mutagenesis

Indexed keywords

ALANINE; ARGININE; GLUTAMATE DEHYDROGENASE; LYSINE; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; COENZYME; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; GENE MUTATION; NONHUMAN; PEPTOSTREPTOCOCCUS; PH; PRIORITY JOURNAL; PROTEIN FOLDING; SITE DIRECTED MUTAGENESIS;

GLUTAMATE DEHYDROGENASE; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR PROBES; MUTAGENESIS, SITE-DIRECTED; NADP; PEPTOSTREPTOCOCCUS; SUBSTRATE SPECIFICITY;

PEPTONIPHILUS ASACCHAROLYTICUS; PEPTOSTREPTOCOCCUS;

EID: 34748915717     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06038.x     Document Type: Article

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