Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 22, 2007, Pages 7012-7020

  Falconer, Robert A ^a   Toth, Istvan ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Drug delivery; Glycolipid; Lipoamino acid; Liposaccharide

Indexed keywords

1 [2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL] 1,5 ANHYDRO DEXTRO GLUCOHEXITOL; 2 (2 AMINODODECYL) 1 (4,5,6,7 TETRACHLOROPHTHALIMIDE); 2 ACETAMIDO 2 DEOXY N (1 AMINO DODECOYL) BETA DEXTRO GLUCOPYRANOSYLAMINE; 2 ACETAMIDO 3,4,6 TRI O ACETYL 2 DEOXY N [[(TERT BUTOXYCARBONYL)AMINO]DODECYL] BETA DEXTRO GLUCOPYRANOSYLAMIDE; 2,3,4,6 TETRA O ACETYL 1 [2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL] 1,5 ANHYDRO DEXTRO GLUCOHEXITOL; 2,3,4,6 TETRA O ACETYL 1 [2 [(TERT BUTOXYCARBONYL)AMINO]DODECYLIDENE] 1,5 ANHYDRO DEXTRO GLUCOHEXITOL; 2,3,4,6 TETRA O ACETYL N [1 [(TERT BUTOXYCARBONYL)AMINO]DODECYL] BETA DEXTRO GLUCOPYRANOSYLAMIDE; 2,3,4,6 TETRA O ACETYL N [[[2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL]OXY]CARBONOTHIOYL] BETA DEXTRO GLUCOPYRANOSYLAMINE; 2,3,4,6 TETRA O ACETYL N [[[2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL]THIO]CARBONOTHIOYL] BETA DEXTRO GLUCOPYRANOSYLAMINE; 2,3,4,6 TETRA O ACETYL N [[[2[(TERT BUTOXYCARBONYL)AMINO]DODECYL]AMINO]CARBONOTHIOYL] BETA DEXTRO GLUCOPYRANOSYLAMINE; 2,3,4,6 TETRA O BENZYL 1 [[2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL]SULPHONYL] 1,5 ANHYDRO DEXTRO GLUCOHEXITOL; [2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL]ETHANETHIOATE; [2 [(TERT BUTOXYCARBONYL)AMINO]DODECYL]ETHANETHIOL; AZIDE; GLYCOLIPID; ISOTHIOCYANIC ACID DERIVATIVE; MONOSACCHARIDE; N (1 AMINO DODECOYL) BETA DEXTRO GLUCOPYRANOSYLAMINE; PIPERACILLIN; SULFONE DERIVATIVE; TERT BUTYL 1 [(2 ACETAMIDO 3,4,6 TRI O ACETYL 2 DEOXY BETA DEXTRO GLUCOPYRANOSYLOXY)METHYL]UNDECYLCARBAMATE; TERT BUTYL 1 [[(2,3,4,6 TETRA O BENZYL BETA DEXTRO GLUCOPYRANOSYL)THIO]METHYL]UNDECYLCARBAMATE; TERT BUTYL N [1 (4,5,6,7 TETRACHLOROPHTHALIMIDOMETHYL)UNDECYL]CARBAMATE; TERT BUTYL N [1 (HYDROXYMETHYL)UNDECYL]CARBAMATE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ABSORPTION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ADMINISTRATION, ORAL; AMINO ACIDS; BACILLUS SUBTILIS; CACO-2 CELLS; CHROMATOGRAPHY, LIQUID; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; GLYCOLIPIDS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MONOSACCHARIDES; PIPERACILLIN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TANDEM MASS SPECTROMETRY;

EID: 34748885101     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.07.048     Document Type: Article

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