Factors affecting immunodetection of hepatitis B surface antigen recombinant mutants

Journal of Medical Virology

Volumn 79, Issue SUPPL. 1, 2007, Pages

  Ali, Akhtar ^a   Pearce, Sandra ^a   Coleman, Paul ^a  

^a ABBOTT DIAGNOSTICS   (United States)

Author keywords

Epitopes; HBsAg; Hepatitis B virus; Immunoassay; Mutations

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; LATEX; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; POLYSTYRENE; REAGENT;

ANTIBODY PRODUCTION; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; EPITOPE MAPPING; FALSE NEGATIVE RESULT; GENETIC TRANSFECTION; HEPATITIS B; HUMAN; IMMOBILIZATION; IMMUNOASSAY; MICROPARTICLE ENZYME IMMUNOASSAY; NONHUMAN; QUANTITATIVE ANALYSIS; SOLID; VIRUS DETECTION; VIRUS MUTATION;

HEPATITIS B VIRUS;

EID: 34748870394     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.20970     Document Type: Conference Paper

References (13)

1. Carman W. 1997. The clinical significance of surface antigen variants of hepatitis B virus. J Viral Hepat 4:11-20.
2. Chang MH. 2006. Impact of hepatitis B vaccination on hepatitis B disease and nucleic acid testing in high-prevalence populations. J Clin Virol 36:S45-S50.
3. Coleman PF. 2006. Detecting hepatitis B surface antigen mutants. Emerg Infect Dis 12:198-203.
4. Coleman P, Chen Y-C, Mushahwar IK. 1999. Immunoassay detection of hepatitis B surface antigen mutants. J Med Virol 59:19-24.
5. Hsu HY, Chang MH, Liaw SH, Ni YH, Chen HL. 1999. Changes of hepatitis B surface antigen variants in carrier children before and after universal vaccination in Taiwan. Hepatology 30:1312-1317.
6. Ireland J, O'Donnell B, Basuni A, Kean J, Wallace L, Lau G, Carman W. 2000. Reactivity of 13 in vitro expressed hepatitis B surface antigen variants in 7 commercial diagnostic assays. Hepatology 31:1176-1182.
7. Jongerius J, Wester M, Cuypers H, van Oostendorp W, Lelie P, van der Poel C, van Leeuwen E. 1998. New hepatitis B virus mutant form in a blood donor that is undetectable in several hepatitis B surface antigen screening assays. Transfusion 38:56-59.
8. Kao JH, Chen DS. 2002. Global control of hepatitis B virus. Lancet Infect Dis 2:395-403.
9. Locarnini S. 2003. Hepatitis B viral resistance: Mechanisms and diagnosis. J Hepatol 39:S124-S132.
10. Margeridon S, Lachaux A, Trepo C, Zoulim F, Kay A. 2005. A quasi-monoclonal anti-HBs response can lead to immune escape of 'wildtype' hepatitis B virus. J Gen Virol 86:1687-1693.
11. Scheiblauer H, Soboll H, Nick S. 2006. Evaluation of 17 CE-marked HBsAg assays with respect to clinical sensitivity, analytical sensitivity, and hepatitis B virus mutant detection. J Med Virol 78:S66-S70.
12. Torresi J, Earnest-Silveira L, Civitico G, Walters TE, Lewin SR, Fyfe J, Locarnini SA, Manns M, Trautwein C, Bock TC. 2002. Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene. Virology 299:88-99.
13. Zuckerman J, Zuckerman A. 2003. Mutations of the surface protein of hepatitis B virus. Antiviral Res 60:75-78.