Advanced rat mammary cancers are growth hormone dependent

Endocrinology

Volumn 148, Issue 10, 2007, Pages 4536-4544

  Shen, Qi ^a   Lantvit, Daniel D ^a   Lin, Qing ^a   Li, Yongjun ^a   Christov, Konstantin ^a   Wang, Zhuohua ^a   Unterman, Terry G ^a,b   Mehta, Rajendra G ^c   Swanson, Steven M ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c Illinois Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR; MESSENGER RNA; METHYLNITROSOUREA; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; STAT3 PROTEIN;

ADVANCED CANCER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INCIDENCE; CONTROLLED STUDY; GROWTH HORMONE DEFICIENCY; HORMONE ACTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

ANIMALS; DISEASE SUSCEPTIBILITY; DRUG ADMINISTRATION SCHEDULE; DWARFISM; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLNITROSOUREA; RATS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY; REMISSION INDUCTION;

EID: 34748861427     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0513     Document Type: Article

References (67)

1. Moon RC 1969 Relationship between previous reproductive history and chemically induced mammary cancer in rats. Int J Cancer 4:312-317
2. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F 1995 Refractoriness to mammary tumorigenesis in parous rats: is it caused by persistent changes in the hormonal environment or permanent biochemical alterations in the mammary epithelia? Carcinogenesis 16:2847-2853
3. Wood TL, Yee D 2000 Introduction: IGFs and IGFBPs in the normal mammary gland and in breast cancer. J Mammary Gland Biol Neoplasia 5:1-5
4. Kleinberg DL 1997 Early mammary development: growth hormone and IGF-1. J Mammary Gland Biol Neoplasia 2:49-57
5. Kleinberg DL 2000 IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis. J Mammary Gland Biol Neoplasia 5:7-17
6. Kelly PA, Bachelot A, Kedzia C, Hennighausen L, Ormandy CJ, Kopchick JJ, Binart N 2002 The role of prolactin and growth hormone in mammary gland development. Mol Cell Endocrinol 197:127-131
7. Lyons WR, Li CH, Johnson RE 1958 The hormonal control of mammary growth and lactation. Recent Prog Horm Res 14:219-248; discussion 248-254
8. Nandi S 1958 Role of somatotropin in mammogenesis and lactogenesis in C3H/He CRGL mice. Science 128:772-774
9. Ng ST, Zhou J, Adesanya OO, Wang J, LeRoith D, Bondy CA 1997 Growth hormone treatment induces mammary gland hyperplasia in aging primates. Nat Med 3:1141-1144
10. Plaut K, Ikeda M, Vonderhaar BK 1993 Role of growth hormone and insulinlike growth factor-I in mammary development. Endocrinology 133:1843-1848
11. Pearson OH, Llerena O, Llerena L, Molina A, Butler T 1969 Prolactin-dependent rat mammary cancer: a model for man? Trans Assoc Am Physicians 82:225-238
12. Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B, Rosner B, Speizer FE, Pollak M 1998 Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351:1393-1396
13. LeRoith D, Roberts Jr CT 2003 The insulin-like growth factor system and cancer. Cancer Lett 195:127-137
14. Wu Y, Cui K, Miyoshi K, Hennighausen L, Green JE, Setser J, LeRoith D, Yakar S 2003 Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors. Cancer Res 63:4384-4388
15. Arteaga CL, Osborne CK 1989 Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor. Cancer Res 49:6237-6241
16. Arteaga CL, Kitten LJ, Coronado EB, Jacobs S, Kull Jr FC, Allred DC, Osborne CK 1989 Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J Clin Invest 84:1418-1423
17. Holly JM, Gunnell DJ, Davey Smith G 1999 Growth hormone, IGF-I and cancer. Less intervention to avoid cancer? More intervention to prevent cancer? J Endocrinol 162:321-330
18. Waters MJ, Conway-Campbell BL 2004 The oncogenic potential of autocrine human growth hormone in breast cancer. Proc Natl Acad Sci USA 101:14992-14993
19. Canzian F, McKay JD, Cleveland RJ, Dossus L, Biessy C, Boillot C, Rinaldi S, Llewellyn M, Chajes V, Clavel-Chapelon F, Tehard B, Chang-Claude J, Linseisen J, Lahmann PH, Pischon T, Trichopoulos D, Trichopoulou A, Zilis D, Palli D, Tumino R, Vineis P, Berrino F, Bueno-de-Mesquita HB, van Gils CH, Peeters PH, Pera G, Barricarte A, Chirlaque MD, Quiros JR, Larranaga N, Martinez-Garcia C, Allen NE, Key TJ, Bingham SA, Khaw KT, Slimani N, Norat T, Riboli E, Kaaks R 2005 Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study. Cancer Epidemiol Biomarkers Prev 14:2316-2325
20. Zhu T, Starling-Emerald B, Zhang X, Lee KO, Gluckman PD, Mertani HC, Lobie PE 2005 Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone. Cancer Res 65:317-324
21. Mukhina S, Mertani HC, Guo K, Lee KO, Gluckman PD, Lobie PE 2004 Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone. Proc Natl Acad Sci USA 101:15166-15171
22. Decouvelaere C, Peyrat JP, Bonneterre J, Djiane J, Jammes H 1995 Presence of the two growth hormone receptor messenger RNA isoforms in human breast cancer. Cell Growth Differ 6:477-483
23. Lincoln DT, Sinowatz F, Temmim-Baker L, Baker HI, Kolle S, Waters MJ 1998 Growth hormone receptor expression in the nucleus and cytoplasm of normal and neoplastic cells. Histochem Cell Biol 109:141-159
24. Mertani HC, Garcia-Caballero T, Lambert A, Gerard F, Palayer C, Boutin JM, Vonderhaar BK, Waters MJ, Lobie PE, Morel G 1998 Cellular expression of growth hormone and prolactin receptors in human breast disorders. Int J Cancer 79:202-211
25. Wang Z, Prins GS, Coschigano KT, Kopchick JJ, Green JE, Ray VH, Hedayat S, Christov KT, Unterman TG, Swanson SM 2005 Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse. Endocrinology 146:5188-5196
26. Zhang X, Mehta RG, Lantvit DD, Coschigano KT, Kopchick JJ, Green JE, Hedayat S, Christov KT, Ray VH, Unterman TG, Swanson SM 2007 Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling. Carcinogenesis 28:143-150
27. Shibata MA, Jorcyk CL, Liu ML, Yoshidome K, Gold LG, Green JE 1998 The C3(1)/SV40 T antigen transgenic mouse model of prostate and mammary cancer. Toxicol Pathol 26:177-182
28. Swanson SM, Unterman TG 2002 The growth hormone-deficient Spontaneous Dwarf rat is resistant to chemically induced mammary carcinogenesis. Carcinogenesis 23:977-982
29. Gullino PM, Pettigrew HM, Grantham FH 1975 N-nitrosomethylurea as mammary gland carcinogen in rats. J Natl Cancer Inst 54:401-414
30. Pearson OH, Manni A 1978 Hormonal control of breast cancer growth in women and rats. Curr Top Exp Endocrinol 3:75-92
31. Russo J, Gusterson BA, Rogers AE, Russo IH, Wellings SR, van Zwieten MJ 1990 Comparative study of human and rat mammary tumorigenesis. Lab Invest 62:244-278
32. Okuma S 1980 Spontaneous dwarf rat. Exp Anim 29:301-305
33. Takeuchi T, Suzuki H, Sakurai S, Nogami H, Okuma S, Ishikawa H 1990 Molecular mechanism of growth hormone (GH) deficiency in the spontaneous dwarf rat: detection of abnormal splicing of GH messenger ribonucleic acid by the polymerase chain reaction. Endocrinology 126:31-38
34. Nogami H, Takeuchi T, Suzuki K, Okuma S, Ishikawa H 1989 Studies on prolactin and growth hormone gene expression in the pituitary gland of spontaneous dwarf rats. Endocrinology 125:964-970
35. Okuma S 1984 Study of growth hormone in spontaneous dwarf rat. Nippon Naibunpi Gakkai Zasshi 60:1005-1014
36. Steel GG 1977 Growth rate of tumours. In: Growth kinetics of tumours. Oxford, UK: Clarendon Press; 5-55
37. Beaver BV, Reed W, Leary S, McKiernan B, Bain F, Schultz R, Bennett BT, Pascoe P, Shull E, Cork LC, Francis-Floyd R, Amass KD, Johnson R, Schmidt RH, Underwood W, Thornton GW, Kohn B 2001 2000 Report of the AMVA Panel on Euthanasia. J Am Vet Med Assoc 218:669-696
38. Van Herck H, Baumans V, Brandt CJ, Boere HA, Hesp AP, van Lith HA, Schurink M, Beynen AC 2001 Blood sampling from the retro-orbital plexus, the saphenous vein and the tail vein in rats: comparative effects on selected behavioural and blood variables. Lab Anim 35:131-139
39. Zhang Y, Guan R, Jiang J, Kopchick JJ, Black RA, Baumann G, Frank SJ 2001 Growth hormone (GH)-induced dimerization inhibits phorbol ester-stimulated GH receptor proteolysis. J Biol Chem 276:24565-24573
40. Frank SJ, Gilliland G, Van Epps C 1994 Treatment of IM-9 cells with human growth hormone (GH) promotes rapid disulfide linkage of the GH receptor. Endocrinology 135:148-156
41. Thordarson G, Semaan S, Low C, Ochoa D, Leong H, Rajkumar L, Guzman RC, Nandi S, Talamantes F 2004 Mammary tumorigenesis in growth hormone deficient spontaneous dwarf rats; effects of hormonal treatments. Breast Cancer Res Treat 87:277-290
42. Nevalainen MT, Xie J, Torhorst J, Bubendorf L, Haas P, Kononen J, Sauter G, Rui H 2004 Signal transducer and activator of transcription-5 activation and breast cancer prognosis. J Clin Oncol 22:2053-2060
43. MacMahon B, Cole P, Lin TM, Lowe CR, Mirra AP, Ravnihar B, Salber EJ, Valaoras VG, Yuasa S 1970 Age at first birth and breast cancer risk. Bull World Health Organ 43:209-221
44. Jansson JO, Ekberg S, Isaksson OG, Eden S 1984 Influence of gonadal steroids on age- and sex-related secretory patterns of growth hormone in the rat. Endocrinology 114:1287-1294
45. Zhu T, Goh EL, Graichen R, Ling L, Lobie PE 2001 Signal transduction via the growth hormone receptor. Cell Signal 13:599-616
46. Butler AA, Yakar S, Gewolb IH, Karas M, Okubo Y, LeRoith D 1998 Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology. Comp Biochem Physiol B Biochem Mol Biol 121:19-26
47. Huang Y, Kim SO, Yang N, Jiang J, Frank SJ 2004 Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements. Mol Endocrinol 18:1471-1485
48. Alexia C, Fallot G, Lasfer M, Schweizer-Groyer G, Groyer A 2004 An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis. Biochem Pharmacol 68:1003-1015
49. Pollak MN, Schernhammer ES, Hankinson SE 2004 Insulin-like growth factors and neoplasia. Nat Rev Cancer 4:505-518
50. Renehan AG, Harvie M, Howell A 2006 Insulin-like growth factor (IGF)-I, IGF binding protein-3, and breast cancer risk: eight years on. Endocr Relat Cancer 13:273-278
51. De W, Breant B, Czernichow P, Asfari M 1995 Growth hormone (GH) and prolactin (PRL) regulate IGFBP-3 gene expression in rat β-cells. Mol Cell Endocrinol 114:43-50
52. Miyoshi K, Shillingford JM, Smith GH, Grimm SL, Wagner KU, Oka T, Rosen JM, Robinson GW, Hennighausen L 2001 Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol 155:531-542
53. Cui Y, Riedlinger G, Miyoshi K, Tang W, Li C, Deng CX, Robinson GW, Hennighausen L 2004 Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol 24:8037-8047
54. Jing N, Tweardy DJ 2005 Targeting Stat3 in cancer therapy. Anticancer Drugs 16:601-607
55. Campbell GS, Meyer DJ, Raz R, Levy DE, Schwartz J, Carter-Su C 1995 Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. J Biol Chem 270:3974-3979
56. Zong CS, Chan J, Levy DE, Horvath C, Sadowski HB, Wang LH 2000 Mechanism of STAT3 activation by insulin-like growth factor I receptor. J Biol Chem 275:15099-15105
57. Huggins C, Briziarelli G, Sutton H 1959 Rapid induction of mammary carcinoma in the rat and the influence of hormones on the tumors. J Exp Med 109:25-54
58. Kennedy BJ 1974 Hormonal therapies in breast cancer. Semin Oncol 1:119-130
59. Luft R, Olivecrona H 1957 Hypophysectomy in treatment of malignant tumors. Cancer 10:789-794
60. Hayward JL, Atkins HJ, Falconer MA, MacLean KS, Salmon LF, Schurr PH, Shaheen CH 1970 Clinical trials comparing transfrontal hypophysectomy with adrenalectomy and with transethmoidal hypophysectomy. In: Gleave EN, Joslin CA, eds. The clinical management of advanced breast cancer. Cardiff, Wales: Alpha Omega Alpha Publishing Co.; 50-53
61. Yang XF, Beamer WG, Huynh H, Pollak M 1996 Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation. Cancer Res 56:1509-1511
62. Pollak M, Blouin MJ, Zhang JC, Kopchick JJ 2001 Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist. Br J Cancer 85:428-430
63. Chen WY, Wight DC, Wagner TE, Kopchick JJ 1990 Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice. Proc Natl Acad Sci USA 87:5061-5065
64. Kahan Z, Varga JL, Schally AV, Rekasi Z, Armatis P, Chatzistamou L, Czompoly T, Halmos G 2000 Antagonists of growth hormone-releasing hormone arrest the growth of MDA-MB-468 estrogen-independent human breast cancers in nude mice. Breast Cancer Res Treat 60:71-79
65. Szepeshazi K, Schally AV, Armatis P, Groot K, Hebert F, Feil A, Varga JL, Halmos G 2001 Antagonists of GHRH decrease production of Gh and IGF-I in mxt mouse mammary cancers and inhibit tumor growth. Endocrinology 142:4371-4378
66. Dagnaes-Hansen F, Duan H, Rasmussen LM, Friend KE, Flyvbjerg A 2004 Growth hormone receptor antagonist administration inhibits growth of human colorectal carcinoma in nude mice. Anticancer Res 24:3735-3742
67. Divisova J, Kuiatse I, Lazard Z, Weiss H, Vreeland F, Hadsell DL, Schiff R, Osborne CK, Lee AV 2006 The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. Breast Cancer Res Treat 98:315-327