The role of sedation tests in identifying sedative drug effects in healthy volunteers and their power to dissociate sedative-related impairments from memory dysfunctions

Journal of Psychopharmacology

Volumn 21, Issue 6, 2007, Pages 579-587

  Wezenberg, E ^a   Sabbe, B G C ^b   Hulstijn, W ^b,c   Ruigt, G S F ^d   Verkes, R J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^d NV ORGANON   (Netherlands)

Author keywords

Antidepressant; Antipsychotics; Benzodiazepine; Histamine H1 antagonists; Memory; Psychomotor; Sedation

Indexed keywords

DEXAMPHETAMINE; HALOPERIDOL; LORAZEPAM; MIRTAZAPINE; OLANZAPINE; PAROXETINE; PLACEBO; SEDATIVE AGENT;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN EXPERIMENT; INFORMATION PROCESSING; MALE; MEMORY DISORDER; MENTAL CAPACITY; MENTAL PERFORMANCE; NORMAL HUMAN; PRIORITY JOURNAL; REACTION TIME; RESPONSE TIME; SACCADIC EYE MOVEMENT; SEDATION; SINGLE DRUG DOSE; SUBSTITUTION REACTION; VELOCITY; VERBAL MEMORY; VISUAL ANALOG SCALE;

ADULT; AFFECT; ANTIPSYCHOTIC AGENTS; AROUSAL; BENZODIAZEPINES; CHOICE BEHAVIOR; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HALOPERIDOL; HISTAMINE H1 ANTAGONISTS; HUMANS; HYPNOTICS AND SEDATIVES; LORAZEPAM; MALE; MEMORY; MEMORY DISORDERS; MIANSERIN; PSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE; QUESTIONNAIRES; REACTION TIME; REFERENCE VALUES; SACCADES; VERBAL LEARNING;

EID: 34748838380     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881106071550     Document Type: Article

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