A comparison of the sedative and amnestic effects of chlorpromazine and lorazepam

Psychopharmacology

Volumn 128, Issue 1, 1996, Pages 67-73

  Green, J F ^a   McElholm, A ^a   King, D J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Chlorpromazine; Lorazepam; Memory; Neuroleptics; Saccadic eye movements; Sedation

Indexed keywords

CHLORPROMAZINE; LORAZEPAM; PLACEBO;

ADULT; AMNESIA; ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; HUMAN; HUMAN EXPERIMENT; INFORMATION PROCESSING; MALE; MEMORY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SACCADIC EYE MOVEMENT; SEDATION; SEMANTICS; VOLUNTEER; WORKING MEMORY;

ADULT; CHLORPROMAZINE; HUMANS; LORAZEPAM; MALE; MEMORY; MENTAL PROCESSES; SACCADES;

EID: 0029999960     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050111     Document Type: Article

References (26)

1. Baddeley AD (1968) A 3 min reasoning test based on grammatical transformation. Pychon Sci 10:341-342
2. Baddeley AD, Emslie H, Nimmo-Smith I (1992) The speeed and capacity of language processing (SCOLP) test. Thames Valley Test, Bury St Edmunds, Suffolk, UK
3. Battig WB, Montague EW (1969) Category nouns tor verbal items in 56 categories: a replication and extension of the Connecticut category nouns. J Exp Psychol 80:1-46
4. Bond AJ, Lader MH (1974) The use of analogue scales in rating subjective feelings. Br J Med Psychol 47:211-218
5. Clare L, McKenna PJ, Mortimer AM, Baddeley AD (1993) Memory in schizophrenia: what is impaired and what is preserved? Neuropsychologia 31 [11]:1225-1241
6. Collins AM, Quillian MR (1969) Retrieval time from semantic memory. J Verb Learn Behav 8:240-247
7. Curran HV, Schifano F, Lader M (1991) Models of memory dysfunction? A comparision of the effects of scopolamine and lorazcpam on memory, psychomotor performance and mood. Psychopharmacology 103:83-90
8. Curran HV, Gorenstein C, Lader M (1993) Comparative amnesic and sedative effects of lorazcpam and oxazepam in healthy volunteers. J Psychopharmacol 7[3]:249-256
9. Danion J-M, Peretti S, Grangé D, Bilik Mv Imbs J-L, Singer L (1992) Effects of chlorpromazinc and lorazepam on explicit memory, repetition priming and cognitive skill learning in healthy volunteers. Psychopharmacology 108:345-351
10. Eitan N, Levin Y, Ben-Artzi E, Levy A, Neumann M (1992) Effects of antipsychotic drugs on memory functions of schizophrenic patients. Acta Psychiatr Scund 85:74-76
11. Frith CD (1984) Schizophrenia, memory and anticholinergic drugs. J Abnorm Psychol 93 [3]:339-341
12. Glue P (1991) The pharmacology of saccadic eye movements. J Psychopharmacol 5 [4]: 377-387
13. Griffiths AN, Marshall RW, Richens A (1984) Saccadic eye movement analysis as a measure of durg effects on human psychomotor performance. Br J Clin Pharmacol 18 [Suppl I]: 73S-82S
14. King DJ (1992) Benzodiazepines. amnesia and sedation: theoretical and clinical issues and controversies. Hum Psychopharmacol 7:79-87
15. King DJ (1993) Measures of neuroleptic effects on cognition and psychomotor performance in healthy volunteers. Hum Psychopharmacol 4:195-209
16. King DJ (1994) Psychomotor impairment and cognitive disturbances induced by neuroleptices. Acta Psychiatr Scand 89 [suppl. 380]:53-58
17. Liljequist R, Linnoila M, Mattila MJ (1978) Effects of diazepam and chlorpromazine on memory functions in man. Eur J Clin Pharmacol 13:339-343
18. Mannion MF, Lynch G, King DJ (1994) Precision of measures of saccadic eye movements and conventional psychomotor function tests. Hum Psychopharmacol 9:37-41
19. Norris H (1971) The action of sedatives on brainstem oculomotor systems in man. Neuropharmacology 10:181-191
20. Roy-Byrnc PP, Cowley DS, Radant A, Hommer D, Greenblatt DJ (1993) Benzodiazepine pharmacodynamics: utility of eye movement measures. Psychopharmacology 110:85-91
21. Rusted JM, Eaton-Williams P, Warburton DM (1991) A comparison of the effects of scopolamine and diazepam on working memory. Psychopharmacology 105:442-445
22. Spohn HE, Strauss ME (1989) Relation of neuroleptic and anticholinergic medication to cognitive functions in schizophrenia. J Abnorm Psychol 98 [4]: 367-380
23. Van Steveninck AL, Kroon JM, Schoemaker HC, Pieters MSM, Breimer DD, Cohen AF (1991) A study comparing the sensitivities of adaptive tracking, eye movement analysis and visual analogue lines to the effects of incremental doses of temazepam in healthy volunteers. Clin Pharmacol Ther 50:172-180
24. Warburton DM, Rusted JM (1989) Memory assessment. Hum Psychopharmacol [Measures Methods] 2:155-178
25. Wechsler D (1985) The measurement and appraisal of human intelligence, 4th edn. Williams and Wilkins, Baltimore
26. Wilson BA, Cockburn JM, Baddeley AD (1985) The Rivermead behavioural memory test. Thames Valley Test, 34-36 High Street. Titchfield, Herts, UK