In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module

Cornea

Volumn 26, Issue 9, 2007, Pages 1141-1143

  Toshida, Hiroshi ^a   Uesugi, Yuko ^a   Ebihara, Nobuyuki ^a   Murakami, Akira ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

Chlorpromazine; Confocal microscope; Corneal deposit; HRT II Rostock Corneal Module

Indexed keywords

CHLORPROMAZINE;

ADULT; ANAMNESIS; ARTICLE; CASE REPORT; CONFOCAL LASER MICROSCOPY; CONFOCAL MICROSCOPY; CONJUNCTIVAL HYPEREMIA; CORNEA; CORNEA ENDOTHELIUM; CORNEA STROMA; DESCEMET MEMBRANE; DRUG DOSE INCREASE; EYE EXAMINATION; FEMALE; HUMAN; IN VIVO STUDY; PHOTOPHOBIA; PRIORITY JOURNAL; SKIN PRURITUS; SLIT LAMP; VISUAL ACUITY;

ADULT; CHLORPROMAZINE; CORNEA; CORNEAL OPACITY; DOPAMINE ANTAGONISTS; FEMALE; HUMANS; MICROSCOPY, CONFOCAL; SCHIZOPHRENIA;

EID: 34748819344     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICO.0b013e318124a42b     Document Type: Article

References (10)

1. Sandvig K. Corneal and lens changes after prolonged treatment with chlorpromazine. Acta Ophthalmol (Copenh). 1965;43:730-734.
2. Hull DS, Csukas S, Green K. Chlorpromazine-induced corneal endothelial phototoxicity. Invest Ophthalmol Vis Sci. 1982;2:502-508.
3. Webber SK, Domniz Y, Sutton GL, et al. Corneal deposition after high-dose chlorpromazine hydrochloride therapy. Cornea. 2001;20:217-219.
4. Phua YS, Patel DV, McGhee CN. In vivo confocal microstructural analysis of corneal endothelial changes in a patient on long-term chlorpromazine therapy. Graefes Arch Clin Exp Ophthalmol. 2005;243:721-723.
5. Guthoff RF, Joachim S. In vivo micromorphology of the cornea: confocal microscopy principles and clinical applications. In: Reinhard T, Larkin F, eds. Essentials in Ophthalmology Cornea and External Eye Disease. Berlin: Springer-Verlag; 2006:173-208.
6. Patel DV, Phua YS. Clinical and microstructural analysis of patients with hyper-reflective corneal endothelial nuclei imaged by in vivo confocal microscopy. Exp Eye Res. 2006;82:682-687.
7. Hollander DA, Aldave AJ. Drug-induced corneal complications. Curr Opin Ophthalmol. 2004;15:541-548.
8. Cavallotti C, Pescosolido N, Artico M, et al. Localization of dopamine receptors in the rabbit cornea. Cornea. 1999;18:721-728.
9. Osborne NN. The occurrence of serotonergic nerves in the bovine cornea. Neurosci Lett. 1983;35:15-18.
10. Dartt DA, McCarthy DM, Mercer HJ, et al. Localization of nerves adjacent to goblet cells in rat conjunctiva. Curr Eye Res. 1995;11:993-1000.