An endothelin A receptor antagonist induces dilatation of sinusoidal endothelial fenestrae: Implications for endothelin-1 in hepatic microcirculation

Journal of Gastroenterology

Volumn 42, Issue 9, 2007, Pages 775-782

  Watanabe, Norihito ^a   Takashimizu, Shinji ^a   Nishizaki, Yasuhiro ^a   Kojima, Seiichiro ^a   Kagawa, Tatehiro ^a   Matsuzaki, Shohei ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Endothelin 1; ETAreceptor; ETBreceptor; hepatic microcirculation; hepatic stellate cell; Scanning electron microscopy; Sinusoidal endothelial fenestrae (SEF)

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOPPLER FLOWMETRY; DRUG EFFICACY; ENDOTHELIUM CELL; LIVER BLOOD FLOW; LIVER CIRCULATION; LIVER SINUSOID; MALE; MANOMETRY; NONHUMAN; PORTAL VEIN; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SCANNING ELECTRON MICROSCOPY; STELLATE CELL;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; HYPERTENSION, PORTAL; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRCULATION; MALE; MICROCIRCULATION; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; PEPTIDES, CYCLIC; RATS; RATS, WISTAR; RECEPTORS, ENDOTHELIN; VASODILATION;

EID: 34648840528     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-007-2093-1     Document Type: Article

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