Axonal transport and cytoskeletal changes in the laminar regions after elevated intraocular pressure

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 8, 2007, Pages 3632-3644

  Balaratnasingam, Chandrakumar ^a   Morgan, William H ^a   Bass, Louise ^a   Matich, Graeme ^a   Cringle, Stephen J ^a   Yu, Dao Yi ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTHIOCYANIC ACID DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; NEUROFILAMENT M PROTEIN; RHODAMINE BETA ISOTHIOCYNATE; UNCLASSIFIED DRUG; NEUROFILAMENT L PROTEIN; NEUROFILAMENT PROTEIN; OXYGEN; TUBULIN;

ANIMAL EXPERIMENT; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; EUTHANASIA; INTRAOCULAR PRESSURE; MICROTUBULE; NERVE FIBER TRANSPORT; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; STAINING; ANIMAL; BIOLOGICAL MODEL; BLOOD; BLOOD PRESSURE; DISEASE MODEL; FEMALE; GLAUCOMA; METABOLISM; OPTIC DISK; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REPRODUCIBILITY; SWINE;

ANIMALS; AXONAL TRANSPORT; BLOOD PRESSURE; CYTOSKELETON; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; INTRAOCULAR PRESSURE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; NEUROFILAMENT PROTEINS; OPTIC DISK; OXYGEN; PHOSPHORYLATION; REPRODUCIBILITY OF RESULTS; STAINING AND LABELING; SUS SCROFA; TUBULIN;

EID: 34648831746     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-1002     Document Type: Article

References (41)

1. Sommer AF, Tielsch JM, Katz J, et al. Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore Eye Survey. Arch Ophthalmol. 1991;109:1090-1095.
2. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80:389-393.
3. Quigley HA, Hohman RM, Addicks EM, Massof RW, Green WR. Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am J Ophthalmol. 1983;95:673-691.
4. Gaasterland D, Tanishima T, Kuwabara T. Axoplasmic flow during chronic experimental glaucoma. 1. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping. Invest Ophthalmol Vis Sci. 1978;17:838-846.
5. Reynolds AJ, Bartlett SE, Hendry IA. Molecular mechanisms regulating the retrograde axonal transport of neurotrophins. Brain Res Brain Res Rev. 2000;33:169-178.
6. Quigley HA, McKinnon SJ, Zack DJ, et al. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthalmol Vis Sci. 2000;41:3460-3466.
7. Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Invest Ophthalmol Vis Sci. 2000;41:764-774.
8. Almenar-Queralt A, Goldstein LS. Linkers, packages and pathways: new concepts in axonal transport. Curr Opin Neurobiol. 2001;11:550-57.
9. Pant HC, Veeranna PG. Regulation of axonal neurofilament phosphorylation. Curr Top Cell Regul. 2000;36:133-150.
10. Lee MK, Cleveland DW. Neuronal intermediate filaments. Annu Rev Neurosci. 1996;19:187-217.
11. Julien JP, Mushynski WE. Neurofilaments in health and disease. Prog Nucleic Acids Res Mol Biol. 1998;61:1-23.
12. Saatman KE, Abai B, Grosvenor AF, et al. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J Cereb Blood Flow Metab. 2003;23:34-42.
13. Anderson DR, Hendrickson A. Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve. Invest Ophthalmol. 1974;13:771-783.
14. Minckler DS, Bunt AH, Johanson GW. Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. Invest Ophthalmol Vis Sci. 1977;16:426-441.
15. Taniguchi T, Shimazawa M, Hara H. Alterations in neurofilament light in optic nerve in rat kainate and monkey ocular hypertension models. Brain Res. 2004;1013:241-248.
16. Westlake WH, Morgan WH, Yu DY. A pilot study of in vivo venous pressures in the pig retinal circulation. Clin Exp Ophthalmol. 2001;29:167-170.
17. Minckler DS, Tso MO, Zimmerman LE. A light microscopic, autoradiographic study of axoplasmic transport in the optic nerve head during ocular hypotony, increased intraocular pressure, and papilledema. Am J Ophthalmol. 1976;82:741-757.
18. Thanos S, Vidal-Sanz M, Aguayo AJ. The use of rhodamine-B-isothiocyanate (RITC) as an anterograde and retrograde tracer in the adult rat visual system. Brain Res. 1987;406:317-321.
19. Ruiz-Ederra J, Garcia M, Hicks D, Vecino E. Comparative study of the three neurofilament subunits within pig and human retinal ganglion cells. Mol Vis. 2004;10:83-92.
20. Ochs S, Dalrymple D, Richards G. Axoplasmic flow in ventral root nerve fibers of the cat. Exp Neurol. 1962;5:349-363.
21. Nadelhaft I. Dynamics of fast axonal transport. Biophys J. 1976; 16:1125-1130.
22. Blum JJ, Reed MC. The transport of organelles in axons. Math Biosci. 1988;90:233-245.
23. Morgan WH, Yu DY, Cooper RL, et al The influence of cerebrospinal fluid pressure on the lamina cribrosa tissue pressure gradient. Invest Ophthalmol Vis Sci. 1995;36:1163-1172.
24. Chihara E, Honda Y. Analysis of orthograde fast axonal transport and nonaxonal transport along the optic pathway of albino rabbits during increased and decreased intraocular pressure. Exp Eye Res. 1981;32:229-239.
25. Derobert YF, Medina MF, Rio JP, et al. Retinal projections in two crocodilian species, Caiman crocodilus and Crocodylus niloticus. Anat Embryol. 1999;200:175-191.
26. Thanos S, Bonhoeffer F. Development of the transient ipsilateral retinotectal projection in the chick embryo: a numerical fluorescence- microscopic analysis. J Comp. Neurol. 1984;224:407-414.
27. Kobbert CF, Apps RF, Bechmann IF, et al. Current concepts in neuroanatomical tracing. Prog Neurobiol. 2000;62:327-351.
28. Hollander H, Makarov F, Stefani FH, Stone J. Evidence of constriction of optic nerve axons at the lamina cribrosa in the normotensive eye in humans and other mammals. Ophthalmic Res. 1995;27:296-309.
29. Brooks DE, Arellano E, Kubilis PS, Komaromy AM. Histomorphometry of the porcine scleral lamina cribrosa surface. Vet Ophthalmol. 1998;1:129-135.
30. Sigal IA, Flanagan JG, Ethier CR. Factors influencing optic nerve head biomechanics. Invest Ophthalmol Vis Sci. 2005;46:4189-4199.
31. Bellezza AJ, Rintalan CJ, Thompson HW, et al. Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma. Invest Ophthalmol Vis Sci. 2003;44:623-637.
32. Morgan WH, Yu DY, Alder VA, et al The correlation between cerebrospinal fluid pressure and retrolaminar tissue pressure. Invest Ophthalmol Vis Sci. 1998;39:1419-1428.
33. Andrews RM, Griffiths PG, Johnson MA, Turnbull DM. Histochemical localisation of mitochondrial enzyme activity in human optic nerve and retina. Br J Ophthalmol. 1999;83:231-235.
34. Kashiwagi K, Ou B, Nakamura S, et al. Increase in dephosphorylation of the heavy neurofilament subunit in the monkey chronic glaucoma model. Invest Ophthalmol Vis Sci. 2003;44:154-159.
35. Aranda-Espinoza H, Carl P, Leterrier JF, et al. Domain unfolding in neurofilament sidearms: effects of phosphorylation and ATP. FEBS Lett. 2002;531:397-401.
36. Gotow T, Tanaka T, Nakamura Y, Takeda M. Dephosphorylation of the largest neurofilament subunit protein influences the structure of crossbridges in reassembled neurofilaments. J Cell Sci. 1994;107:1949-1957.
37. Goldstein ME, Sternberger NH, Sternberger LA. Phosphorylation protects neurofilaments against proteolysis. J Neuroimmunol. 1987;14:149-160.
38. Ou B, Ohno S, Tsukahara S. Ultrastructural changes and immunocytochemical localization of microtubule-associated protein 1 in guinea pig optic nerves after acute increase in intraocular pressure. Invest Ophthalmol Vis Sci. 1998;39:963-971.
39. Johansson JO. The lamina cribrosa in the eyes of rats, hamsters, gerbils and guinea pigs. Acta Anat. 1987;128:55-62.
40. Fernandez HL, Burton PR, Samson FE. Axoplasmic transport in the crayfish nerve cord: the role of fibrillar constituents of neurons. J Cell Biol. 1971;51:176-192.
41. Morgan WH, Chauhan BC, Yu DY, et al. Optic disc movement with variations in intraocular and cerebrospinal fluid pressure. Invest Ophthalmol Vis Sci. 2002;43:3236-3242.