Oral cryotherapy reduces mucositis and opioid use after myeloablative therapy - A randomized controlled trial

Supportive Care in Cancer

Volumn 15, Issue 10, 2007, Pages 1155-1161

  Svanberg, Anncarin ^a   Birgegård, Gunnar ^a   Öhrn, Kerstin ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b DALARNA UNIVERSITY   (Sweden)

Author keywords

Bone marrow transplantation; Mucositis; Opioid use; Oral cryotherapy; Oral pain

Indexed keywords

MORPHINE; OPIATE;

ADULT; ARTICLE; BONE MARROW TRANSPLANTATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYOTHERAPY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUTH HYGIENE; MOUTH PAIN; MUCOSA INFLAMMATION; MYELOABLATIVE CONDITIONING; PAIN ASSESSMENT; PAIN THRESHOLD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; SCORING SYSTEM; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; VISUAL ANALOG SCALE;

ADULT; ANALGESICS, OPIOID; BONE MARROW TRANSPLANTATION; CRYOTHERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; MYELOABLATIVE AGONISTS; STOMATITIS;

EID: 34648830810     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-007-0245-8     Document Type: Article

References (34)

1. McGuire D et al (1993) Pattern of mucositis and pain in patients receiving preparatic chemotherapy and bone marrow transplantation. Oncol Nurs Forum 20:1493-1502
2. Woo SB et al (1993) A longitudinal study of oral ulcerative mucositis in bone marrow transplant recipients. Cancer 72(5):1612-1617
3. Sonis S (1998) Mucositis as a biological process: a new hypothesis for the development of chemotherpy-induced stomatotoxity. Oral Oncol 34:39-43
4. Bellm LA et al (2000) Patient reports of complications of bone marrow transplantation. Support Care Cancer 8(1):33-39
5. Sonis ST et al (2001) Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 19(8):2201-2205
6. Sonis S (2004) The pathobiology of mucositis. Nat Rev Cancer 4:227-284
7. Lalla R, Wang Z, Sonis S (2005) Role of the cyclooxygenase pathway in chemotherapy-induced oral mucositis. In: 17th MASCC/ISOO international symposium. Geneva, Switzerland
8. Lunn R (1998) Oral management of the cancer patient. Part II: chemotherapy. Probe 32(2):58-65, 68
9. Sonis ST et al (2004) Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 100(9 Suppl):1995-2025
10. Miaskowski C (1990) Oral complications of cancer therapies. Management of mucositis during therapy. NCI Monogr (9):95-98
11. Persson L, Hallberg I (1995) Acute leukaemia and malignant lymphoma patients' experiences of disease, treatment and nursing care during the active treatment phase: an explorative study. Eur J Cancer Care 4(3):133-142
12. McGuire DB (2004) Occurrence of cancer pain. J Natl Cancer Inst Monogr (32):51-56
13. McGuire DB et al (1998) Acute oral pain and mucositis in bone marrow transplant and leukemia patients: data from a pilot study. Cancer Nurs 21(6):385-393
14. Meropol NJ et al (2003) Randomized phase I trial of recombinant human keratinocyte growth factor plus chemotherapy: potential role as mucosal protectant. J Clin Oncol 21(8):1452-1458
15. Larson L et al (2000) Comparison of perceived symptoms of patients undergoing bone marrow transplant and the nurses caring for them. Oncol Nurs Forum 20:81-87
16. Sonis S, Woods P, White B (1990) Oral complications of cancer therapies. Pretreatment oral assessment. Natl Cancer Inst Monogr 9:29-32
17. Zerbe MB et al (1992) Relationships between oral mucositis and treatment variables in bone marrow transplant patients. Cancer Nurs 15(3):196-205
18. Muus P et al (1992) Intencification of the conditioning regimen for allogeneic bone marrow transplantation in recipients of T-cell deplated grafts by the addition of anthracyclines. Leuk Lymphoma 7:11-14
19. Brincker H, Christensen BE (1993) Acute mucocutaneous toxicity following high-dose hydroxyurea. Cancer Chemother Pharmacol 32(6):496-497
20. Jones J et al (2006) Epidemiology of treatment-associated mucosal injury after treatment with newer regimens for lymphoma, breast, lung, or colorectal cancer. Support Care Cancer 14:505-515
21. Mahood DJ et al (1991) Inhibition of fluorouracil-induced stomatitis by oral cryotherapy. J Clin Oncol 9(3):449-452
22. Cascinu S et al (1994) Oral cooling (cryotherapy), an effective treatment for the prevention of 5-fluorouracil-induced stomatitis. Eur J Cancer B Oral Oncol 30B(4):234-236
23. Tartarone A et al (2005) Prevention of high-dose melphalan-induced mucositis by cryotherapy. Leuk Lymphoma 46:633-634
24. Yokomizo H et al (2004) Prophylactic efficacy of allopurinol ice ball for leucovorin/5 fluorouracil therapy-induced stomatitis. Anticancer Res 24:1131-1134
25. Aisa Y et al (2005) Oral Cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 13(4):266-269
26. Mori T et al (2006) Brief oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 14(4):392-395
27. Migliorati C, Oberle-Edwards L, Schubert M (2006) The role of alternative and natural agents, cryotherapy and/or laser for management of alimentary mucositis. Support Care Cancer 14:533-540
28. Karagözoglu S, Ulusoy M (2004) Chemotherapy: the effect of oral cryotherapy on the development of mucositis. Journal of Clinical Nursing 14:754-765
29. Lilleby K et al (2006) A prospective, randomized study of cryotherapy during administration of high-dose melphalan to decrease the severity and duration or oral mucositis in patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 37:1031-1035
30. Worthington H, Clarkson J, Eden O (2006) Interventions for preventing oral mucositis for patients with cancer receiving treatment (review). Cochrane Database Syst Rev 2:CD000978
31. Rocke L et al (1993) A randomized clinical trial of two different duration of oral cryotherapy for prevention of 5-fluorouracil-related stomatitis. Cancer 72(7):2234-2238
32. Sonis ST et al (1999) Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group. Cancer 85(10):2103-2113
33. Rubenstein EB et al (2004) Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer 100(9 Suppl):2026-2046
34. Blijlevens N, Donnelly J, DePauw B (2005) Inflammatory response to mucosal barrier injury after myeloablative therapy in allogeneic stem cell transplant recipients. Bone Marrow Transplant 36:703-707