Interleukin-1 receptor antagonist is associated with both lipid metabolism and inflammation in rheumatoid arthritis

Clinical and Experimental Rheumatology

Volumn 25, Issue 4, 2007, Pages 617-620

  Ljung, Lotta ^a   Olsson, Tommy ^a   Engstrand, Stefan ^a   Wållberg Jonsson, Solveig ^a   Söderberg, Stefan ^a   Rantapää Dahlqvist, Solbritt ^a  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Apolipoprotein A I; Apolipoproteins B; Interleukin 1 receptor antagonist; Leptin; Rheumatoid arthritis

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; BIOLOGICAL MARKER; HAPTOGLOBIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; LEPTIN; OROSOMUCOID; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; INFLAMMATION; LIPID METABOLISM; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; APOLIPOPROTEINS; APOLIPOPROTEINS B; ARTHRITIS, RHEUMATOID; BODY MASS INDEX; FEMALE; HAPTOGLOBINS; HUMANS; INFLAMMATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; LEPTIN; LIPID METABOLISM; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 34648828274     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. RANTAPÄÄ-DAHLQVIST S, WÅLLBERG-JONSSON S, DAHLEN G: Lipoprotein (a), lipids, and lipoproteins in patients with rheumatoid arthritis. Ann Rheum Dis 1991; 50: 366-8.
2. PARK YB, LEE SK, LEE WK et al.: Lipid profiles in untreated patients with rheumatoid arthritis. J Rheumatol 1999; 26: 1701-4.
3. WÅLLBERG-JONSSON S, JOHANSSON H, ÖHMAN ML, RANTAPÄÄ-DAHLQVIST S: Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset. J Rheumatol 1999; 26: 2562-71.
4. WÅLLBERG JONSSON S, BACKMAN C, JOHNSON O et al.: Increased prevalence of atherosclerosis in patients with medium term rheumatoid arthritis. J Rheumatol 2001; 28: 2597-602.
5. JUGE-AUBRY CE, SOMM E, GIUSTI V et al.: Adipose tissue is a major source of interleukin-1 receptor antagonist: Upregulation in obesity and inflammation. Diabetes 2003; 52: 1104-10.
6. LAU DCM DHILLON B, YAN H, SZMITKO PE, VERMA S: Adipokines: molecular links between obesity and atherosclerosis. Am J Physiol Heart Circ Physiol 2005; 288: H2031-41.
7. ARNETT FC, EDWORTHY SM, BLOCH DA et al.: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.
8. PREVOO MLL, VAN'T HOF MA, KUPER HH, VAN LEEUWEN MA, VAN DE PUTTE LBA, VAN RIEL PLCM: Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-8.
9. WALLDIUS G, JUNGNER I: ApolipoproteRn B and apolipoprotein A-I: risk indicators of coronary heart disease and targets for lipid-modifying therapy. J Intern Med 2004; 255: 188-205.
10. ROHRER L, HERSBERGER M, VON ECKARDSTEIN A: High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease. Curr Opin Lipidol 2004; 15: 269-78.
11. HYKA N, DAYER JM, MODOUX C et al.: Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes. Blood 2001; 97: 2381-9.
12. BURGER D, DAYER JM: High-density lipoprotein-associated apolipoprotein A-I: The missing link between infection and chronic inflammation? Autoimmun Rev 2002; 1: 111-7.
13. ANDERS HJ, RIEL M, HEUFELDER A, LOCH O, SCHATTENKIRCHNER. M: Leptin serum levels are not correlated with disease activity in patients with rheumatoid arthritis. Metabolism 1999; 48: 745-8.
14. POPA C, NETEA MG, RADSTAKE TR, VAN RIEL PL, BARRERA P, VAN DER MEER JW: Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis. Ann Rheum Dis 2005; 64: 1195-8.
15. MEIER CA, BOBBIONI E, GABAY C, ASSIMACOPOULOS-JEANNET F, GOLAY A, DAYER JM: IL-1 receptor antagonist serum levels are increased in human obesity: A possible link to the resistance to leptin? J Clin Endocrinol Metab 2002; 87: 1184-8.