Structure and function of suburothelial myofibroblasts in the human urinary bladder under normal and pathological conditions;Struktur und funktion der suburothelialen myofibroblasten in der humanen harnblase unter normalen und pathologischen bedingungen

Urologe - Ausgabe A

Volumn 46, Issue 9, 2007, Pages 1197-1202

  Neuhaus, J ^a   Heinrich, M ^a   Schlichting, N ^b   Oberbach, A ^b   Fitzl, G ^b   Schwalenberg, T ^a   Horn, L C ^b   Stolzenburg, J U ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cell culture; Coupling; Human urinary bladder; Myofibroblast; Neurotransmitter receptor

Indexed keywords

CONNEXIN 43; CYTOKINE; MUSCARINIC RECEPTOR; PURINE RECEPTOR;

ARTICLE; BLADDER; BLADDER BIOPSY; BLADDER CARCINOMA; CELL FUNCTION; CELL STRUCTURE; CYSTITIS; ELECTRON MICROSCOPY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MUSCLE CELL; MYOFIBROBLAST;

ACTINS; AGED; AGED, 80 AND OVER; BASEMENT MEMBRANE; BIOPSY; CONNEXIN 43; CYSTITIS; FEMALE; FIBROBLASTS; FIBRONECTINS; HUMANS; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MUCOUS MEMBRANE; MYOBLASTS, SMOOTH MUSCLE; RECEPTORS, MUSCARINIC; RECEPTORS, PURINERGIC; URINARY BLADDER DISEASES; URINARY BLADDER NEOPLASMS; URINARY INCONTINENCE, URGE; URODYNAMICS; UROTHELIUM;

EID: 34648820048     PISSN: 03402592     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00120-007-1480-9     Document Type: Article

References (14)

1. Arora PD, Narani N, McCulloch CA (1999) The compliance of collagen gels regulates transforming growth factor-beta induction of alpha-smooth muscle actin in fibroblasts. Am J Pathol 154: 871-882
2. Buoro S, Ferrarese P, Chiavegato A et al. (1993) Myofibroblast-derived smooth muscle cells during remodelling of rabbit urinary bladder wall induced by partial outflow obstruction. Lab Invest 69: 589-602
3. Eyden B (2001) The fibronexus in reactive and tumoral myofibroblasts: further characterisation by electron microscopy. Histol Histopathol 16: 57-70
4. Eyden B (2001) The myofibroblast: an assessment of controversial issues and a definition useful in diagnosis and research. Ultrastruct Pathol 25: 39-50
5. Eyden B (2004) Fibroblast phenotype plasticity: relevance for understanding heterogeneity in.,fibroblastic" tumors. Ultrastruct Pathol 28: 307-319
6. Fry CH, Ikeda Y, Harvey R et al. (2004) Control of bladder function by peripheral nerves: avenues for novel drug targets. Urology 63: 24-31
7. Hinz B, Gabbiani G (2003) Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling. Thromb Haemost 90: 993-1002
8. Hinz B, Mastrangelo D, Iselin CE et al. (2001) Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol 159: 1009-1020
9. McHale NG, Hollywood MA, Sergeant GP et al. (2006) Organization and function of ICC in the urinary tract. J Physiol 576: 689-694
10. Mukerji G, Yiangou Y, Grogono J et al. (2006) Localization of M2 and M3 muscarinic receptors in human bladder disorders and their clinical correlations. J Urol 176: 367-373
11. Neuhaus J, Pfeiffer F, Wolburg H et al. (2005) Alterations in connexin expression in the bladder of patients with urge symptoms. BJU Int 96: 670-676
12. Owens GK, Kumar MS, Wamhoff BR (2004) Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801
13. Singer II, Kazazis DM, Kawka DW (1985) Localization of the fibronexus at the surface of granulation tissue myofibroblasts using double-label immunogold electron microscopy on ultrathin frozen sections. Eur J Cell Biol 38: 94-101
14. Sui GP, Rothery S, Dupont E et al. (2002) Gap junctions and connexin expression in human suburothelial interstitial cells. BJU Int 90: 118-129