A double-blind, crossover, randomized dose-comparison trial of granisetron for the prevention of acute and delayed nausea and emesis in children receiving moderately emetogenic carboplatin-based chemotherapy

Supportive Care in Cancer

Volumn 15, Issue 10, 2007, Pages 1163-1168

  Berrak, Su G ^a,d   Ozdemir, Nihal ^a   Bakirci, Nadi ^a   Turkkan, Emine ^b   Canpolat, Cengiz ^a   Beker, Bahar ^a   Yoruk, Asim ^c  

^a MARMARA UNIVERSITY   (Turkey)

^b OKMEYDANI EDUCATION AND RESEARCH HOSPITAL   (Turkey)

^c Ministry of Health Goztepe Educational and Research Hospital   (Turkey)

^d NONE   (Turkey)

Author keywords

Antiemetic; Chemotherapy; Dose comparison; Efficacy; Granisetron

Indexed keywords

CARBOPLATIN; GRANISETRON; VINCRISTINE;

ABSENCE OF SIDE EFFECTS; ADOLESCENT; ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CHEMOTHERAPY INDUCED EMESIS; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG INFUSION; DRUG TOLERABILITY; EYE TUMOR; FEMALE; HUMAN; MALE; MULTIPLE CYCLE TREATMENT; NAUSEA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADOLESCENT; ADULT; ANTIEMETICS; ANTINEOPLASTIC AGENTS; CARBOPLATIN; CHILD; CHILD, PRESCHOOL; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE BIND INTERACTION; DRUG THERAPY; FEMALE; GRANISETRON; HUMANS; INFANT; MALE; NAUSEA; TREATMENT OUTCOME; VOMITING;

EID: 34648819247     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-007-0242-y     Document Type: Article

References (30)

1. ASHP (1999) Therapeutic guidelines on the pharmacologic management of nausea and vomiting in adult and pediatric patients receiving chemotherapy or radiation therapy or undergoing surgery. Am J Health-Syst Pharm 56:729-764
2. Aapro M (2004) Granisetron: an update on its clinical use in the management of nausea and vomiting. Oncologist 9:673-686
3. Aapro MS, Thuerlimann B, Sessa C et al; Swiss Research Group for Clinical Cancer Research (2003) A randomized double-blind trial to compare the clinical efficacy of granisetron with metoclopramide, both combined with dexamethasone in the prophylaxis of chemotherapy-induced delayed emesis. Ann Oncol 14:291-297
4. Aksoylar S, Akman SA, Ozgenc F et al (2001) Comparison of tropisetron and granisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy. Pediatr Hematol Oncol 18:397-406
5. Craft AW, Price L, Eden OB et al (1995) Granisetron as antiemetic therapy in children with cancer. Med Pediatr Oncol 25:28-32
6. de Boer-Dennert M, de Wit R, Schmitz PI et al (1997) Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists. Br J Cancer 76:1055-1061
7. Gandara D (1991) Progress in the control of acute and delayed emesis induced by cisplatin. Eur J Cancer 27:S9-S11 (discussion S22)
8. Gandara DR, Roila F, Warr D et al (1998) Consensus proposal for 5HT3 antagonists in the prevention of acute emesis related to highly emetogenic chemotherapy. Dose, schedule, and route of administration. Support Care Cancer 6:237-243
9. Gralla RJ, Osoba D, Kris MG et al (1999) Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical Oncology. J Clin Oncol 17:2971-2994
10. Gregory RE, Ettinger DS (1998) 5-HT3 receptor antagonists for the prevention of chemotherapy-induced nausea and vomiting. A comparison of their pharmacology and clinical efficacy. Drugs 55:173-189
11. Hahlen K, Quintana E, Pinkerton CR et al (1995) A randomized comparison of intravenously administered granisetron versus chlorpromazine plus dexamethasone in the prevention of ifosfamide-induced emesis in children. J Pediatr 126:309-313
12. Herrstedt J, Koeller JM, Roila F et al (2005) Acute emesis: moderately emetogenic chemotherapy. Support Care Cancer 13:97-103
13. Holdsworth MT, Raisch DW, Frost J (2006) Acute and delayed nausea and emesis control in pediatric oncology patients. Cancer 106:931-940
14. Jacobson SJ, Shore RW, Greenberg M et al (1994) The efficacy and safety of granisetron in pediatric cancer patients who had failed standard antiemetic therapy during anticancer chemotherapy. Am J Pediatr Hematol/Oncol 16:231-235
15. Kamanabrou D (1992) Intravenous granisetron-establishing the optimal dose. The Granisetron Study Group. Eur J Cancer 28A:S6-S11
16. Koizumi W, Tanabe S, Nagaba S et al (2003) A double-blind, crossover, randomized comparison of granisetron and ramosetron for the prevention of acute and delayed cisplatin-induced emesis in patients with gastrointestinal cancer: is patient preference a better primary endpoint? Chemotherapy 49:316-323
17. Komada Y, Matsuyama T, Takao A et al (1999) A randomised dose-comparison trial of granisetron in preventing emesis in children with leukaemia receiving emetogenic chemotherapy. Eur J Cancer 35:1095-1101
18. Kris MG, Hesketh PJ, Herrstedt J et al (2005) Consensus proposals for the prevention of acute and delayed vomiting and nausea following high-emetic-risk chemotherapy. Support Care Cancer 13:85-96
19. Lemerle J, Amaral D, Southall DP et al (1991) Efficacy and safety of granisetron in the prevention of chemotherapy-induced emesis in paediatric patients. Eur J Cancer 27:1081-1083
20. Luisi FA, Petrilli AS, Tanaka C et al (2006) Contribution to the treatment of nausea and emesis induced by chemotherapy in children and adolescents with osteosarcoma. Sao Paulo Med J 124:61-65
21. Mabro M, Cohn R, Zanesco L et al (2000) Oral granisetron solution as prophylaxis for chemotherapy-induced emesis in children: double-blind study of 2 doses. Bull Cancer 87:259-264 (French)
22. Matsui K, Fukuoka M, Takada M et al (1996) Randomised trial for the prevention of delayed emesis in patients receiving high-dose cisplatin. Br J Cancer 73:217-221
23. Miyajima Y, Numata S, Katayama I et al (1994) Prevention of chemotherapy-induced emesis with granisetron in children with malignant diseases. Am J Pediatr Hematol/Oncol 16:236-241
24. Navari R, Gandara D, Hesketh P et al (1995) Comparative clinical trial of granisetron and ondansetron in the prophylaxis of cisplatin-induced emesis. The Granisetron Study Group. J Clin Oncol 13:1242-1248
25. Orchard PJ, Rogosheske J, Burns L et al (1999) A prospective randomized trial of the antiemetic efficacy of ondansetron and granisetron during bone marrow transplantation. Biol Blood Marrow Transplant 5:386-393
26. Redmond K (1996) Advances in supportive care. Eur J Cancer Care (Engl) 4:1-7
27. Riviere A (1994) Dose finding study of granisetron in patients receiving high-dose cisplatin chemotherapy. The Granisetron Study Group. Br J Cancer 68:967-971
28. Soukop M (1994) A dose-finding study of granisetron, a novel antiemetic, in patients receiving high-dose cisplatin. Granisetron Study Group. Support Care Cancer 2:177-183
29. Tsuchida Y, Hayashi Y, Asami K et al (1999) Effects of granisetron in children undergoing high-dose chemotherapy: a multi-institutional, cross-over study. Int J Oncol 14:673-679
30. Yalcin S, Tekuzman G, Baltali E et al (1999) Serotonin receptor antagonists in prophylaxis of acute and delayed emesis induced by moderately emetogenic, single-day chemotherapy: a randomized study. Am J Clin Oncol 22:94-96