Pharmacokinetics and metabolism of neferine in rats after a single oral administration

Biopharmaceutics and Drug Disposition

Volumn 28, Issue 7, 2007, Pages 361-372

  Huang, Ying ^a   Bai, Yun ^b   Zhao, Libo ^a   Hu, Ting ^a   Hu, Benrong ^a   Wang, Jialing ^a   Xiang, Jizhou ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

HPLC; LC MS; Metabolism; Neferine; Pharmacokinetics

Indexed keywords

ALKALOID DERIVATIVE; BISBENZYLISOQUINOLINE ALKALOID; CYTOCHROME P450 2D6; DRUG METABOLITE; ISOLEINSININE; LEINSININE; NEFERINE; QUINIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG STRUCTURE; DRUG TISSUE LEVEL; FEMALE; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY PARENCHYMA; LIQUID CHROMATOGRAPHY; LUNG PARENCHYMA; MALE; MASS SPECTROMETRY; NONHUMAN; RAT; SINGLE DRUG DOSE;

ADMINISTRATION, ORAL; ANIMALS; BENZYLISOQUINOLINES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HALF-LIFE; MALE; MICROSOMES, LIVER; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 34548849794     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.556     Document Type: Article

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