Antinociceptive, anti-inflammatory and antipyretic effects of Muntingia calabura aqueous extract in animal models

Journal of Natural Medicines

Volumn 61, Issue 4, 2007, Pages 443-448

  Zakaria, Z A ^a   Nor Hazalin, N A Mohd ^b   Zaid, S N H Mohd ^b   Ghani, M Abdul ^b   Hassan, M H ^b   Gopalan, H K ^b   Sulaiman, M R ^c  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b Universiti Industri Selangor   (Malaysia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Anti inflammatory; Antinociceptive; Antipyretic; Aqueous extract; Muntingia calabura

Indexed keywords

CARRAGEENAN; FORMALDEHYDE; MUNTINGIA CALABURA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ANTIPYRETIC ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEVER; MALE; MEDICINAL PLANT; MUNTINGIA CALABURA; NONHUMAN; PAW EDEMA; RAT; SACCHAROMYCES CEREVISIAE; SUPERNATANT;

EID: 34548846143     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-007-0167-2     Document Type: Article

References (38)

1. Morton JF (1987) Jamaica cherry. In: Morton JF (ed) Fruits of warm climates. Julia F Morton, Miami, Florida, pp 65-69
2. Jensen M (1999) Trees commonly cultivated in Southeast Asia: an illustrated field guide, 2nd edn. FAO Corporate Document Repository, Craftsman Press, Bangkok, Thailand
3. Verheij EWM, Coronel RE (1992) Plant resources of Southeast Asia, no. 2: edible fruits and nuts. PROSEA, Bogor, Indonesia
4. Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V (1991) Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots. J Nat Prod 54(1):196-206
5. Su N, Jung Park E, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD (2003) Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry 63(30):335-341
6. Zakaria ZA, Sulaiman MR, Mat Jais AM, Somchit MN, Jayaraman KV, Balakhrisnan G, Abdullah FC (2006) The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice. Fundam Clin Pharmacol 20:365-372
7. Zakaria ZA, Fatimah CA, Mat Jais AM, Zaiton H, Henie EFP, Sulaiman MR, Somchit MN, Thenamutha M, Kasthuri D (2006) The in vitro antibacterial activity of Muntingia calabura extracts. Int J Pharmacol 2(3):290-293
8. Zakaria ZA, Zaiton H, Henie EFP, Mat Jais AM, Kasthuri D, Thenamutha M, Othman FW, Nazaratulmawarina R, Fatimah CA (2006) The in vitro antibacterial activity of Corchorus olitorius and Muntingia calabura extracts. J Pharmacol Toxicol 1(2):108-114
9. Ikhiri K, Boureima D, Dan-Kouloudo D-D (1992) Chemical screening of medicinal plants used in the traditional pharmacopoeia of Niger. Int J Pharmacog 30:251-262
10. Hunskaar S, Hole K (1987) The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 30:103-104
11. Chakraborty A, Devi RKB, Rita S, Sharatchandra K, Singh TI (2004) Preliminary studies on antiinflammatory and analgesic activities of Spilanthes acmella in experimental animal models. Ind J Pharmacol 36(3):148-150
12. Reanmongkol W, Subhadhirasakul S, Pairat C, Poungsawai C, Choochare W (2002) Antinociceptive activity of Dyera costulata extract in experimental animals. Songklanakarin J Sci Technol 24(2):227-234
13. Bentley GA, Newton SH, Starr J (1981) Evidence for an action of morphine and the enkephalins on sensory nerve endings in the mouse peritoneum. Br J Pharmacol 73:325-332
14. Bentley GA, Newton SH, Starr J (1983) Studies on the antinociceptive action of alpha-agonist drugs and their interactions with opioid mechanisms. Br J Pharmacol 79:125-134
15. Dharmasiri MG, Ratnasooriya WD, Thabrew MI (2003) Water extract of leaves and stems of preflowering but not flowering plants of Anisomeles indica possesses analgesic and antihyperalgesic activities in rats. Pharmaceut Biol 41:37-44
16. Hunskaar S, Fasmer OB, Hole K (1985) Formalin test in mice: a useful technique for evaluating mild analgesics. J Neurosci Methods 14:69-76
17. Heapy CG, Jamieson A, Russell NJW (1987) Afferent C-fiber and A-delta activity in models of inflammation. Br J Pharmacol 90:164-170
18. Malmberg AB, Yaksh TL (1992) Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat. J Pharmacol Exp Ther 263(1):136-146
19. Tjølsen A, Berge OG, Hunskaar S, Rosland JH, Hole K (1992) The formalin test: an evaluation of the method. Pain 51:5-17
20. Chan TF, Tsai HY, Wu TS (1995) Anti-inflammatory and analgesic activities from roots of Angelica pubescens. Planta Med 61:2-8
21. Sulaiman MR, Somchit MN, Israf DA, Ahmad Z, Moin S (2004) Antinociceptive effect of Melastoma malabathricum ethanolic extract in mice. Fitoterapia 75:667-672
22. Zakaria ZA, Safarul M, Sulaiman MR, Mat Jais AM, Somchit MN, Abdullah FC (2007) The antinociceptive action of aqueous extract from Muntingia calabura leaves: the role of opioid receptors. Med Princ Pract 16:130-136
23. Winter CA, Risley EA, Nuss GW (1962) Carrageenan-induced edema in hind paws of the rat as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med 111:544-547
24. Damas J, Remacle-Volon G, Deflandre E (1986) Further studies of the mechanism of counter irritation by turpentine. Naunyn Schmiedebergs Arch Pharmacol 332:196-200
25. Joseph SM, George MC, Rajasekharan Nair J, Priya Senan V, Pillai D, Sherief PM (2005) Effect of feeding cuttlefish liver oil on immune function, inflammatory response and platelet aggregation in rats. Curr Sci 88(3):507-510
26. di Meglio P, Ianaro A, Ghosh S (2005) Amelioration of acute inflammation by systemic administration of a cell-permeable peptide inhibitor of NF-kappaB activation. Arthritis Rheum 52(3):951-958
27. Uzcátegui B, Ávila D, Suárez-Roca H, Quintero L, Ortega J, González B (2004) Anti-inflammatory, antinociceptive, and antipyretic effects of Lantana trifolia Linnaeus in experimental animals. Invest Clín 45(4):317-322
28. Katzung BG (1995) Basic and clinical pharmacology, 6th edn. Appleton and Lange, Stanford, Connecticut
29. Tripathi KD (2001) Essentials of medical pharmacology, 4th edn. Jaypee Brothers, New Delhi, India
30. Katzung BG (1995) Basic and clinical pharmacology, 6th edn. Appleton and Lange, Stanford, Connecticut p 23
31. Kim HP, Son KH, Chang HW, Kang SS (2004) Anti-inflammatory plant flavonoids and cellular action mechanisms. J Pharmacol Sci 96(3):229-245
32. Ramesh M, Rao YN, Rao AV, Prabhakar MC, Rao CS, Muralidhar N, Reddy BM (1998) Antinociceptive and anti-inflammatory activity of a flavonoid isolated from Caralluma attenuata. J Ethnopharmacol 62:63-66
33. Beirith A, Santos ARS, Calixto JB, Hess SC, Messana I, Ferrari F, Yunes RA (1999) Study of the antinociceptive action of the ethanolic extract and the triterpene 24-hydroxytormentic acid isolated from the stem bark of Ocotea suaveolens. Planta Med 65:50-55
34. Ghosh D, Thejomoorthy P, Veluchamy P (1983) Anti-inflammatory and analgesic activities of oleanolic acid 3-/3-glucoside (RDG-1) from Randia dumetorum (Rubiaceae). Ind J Pharmacol 15(4):331-342
35. Karumi Y, Onyeyili P, Ogugbuaja VO (2003) Anti-inflammatory and antinociceptive (analgesic) properties of Momordical balsamina Linn. (Balsam apple) leaves in rats. Pak J Biol Sci 6(17):1515-1518
36. Starec M, Waitzov'a D, Elis J (1988) Evaluation of the analgesic effect of RG-tannin using the "hot plate" and "tail flick" method in mice (in Czech). Cesk Farm 37:319-321
37. Attaway DH, Zaborsky OR (1993) Marine biotechnology, vol 1: pharmaceutical and bioactive natural products. Plenum Press, New York
38. Dawson TM, Snyder SH (1994) Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J Neurosci 14:5147-5159